Topological Mapping of Neutrophil Cytochrome b Epitopes with Phage-display Libraries

Experiments in molecular genetics

1972 • 28,260 citations

Searching for Peptide Ligands with an Epitope Library

1990 • 2,080 citations

Active Oxygen Species and the Functions of Phagocytic Leukocytes

1980 • 1,124 citations

Peptides on phage: a vast library of peptides for identifying ligands.

1990 • 928 citations

Random Peptide Libraries: a Source of Specific Protein Binding Molecules

1990 • 910 citations

Cloning the gene for an inherited human disorder—chronic granulomatous disease—on the basis of its chromosomal location

1986 • 839 citations

[15] Libraries of peptides and proteins displayed on filamentous phage

1993 • 770 citations

The superoxide‐generating oxidase of phagocytic cells

1991 • 564 citations

Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000.

1987 • 459 citations

The glycoprotein encoded by the X-linked chronic granulomatous disease locus is a component of the neutrophil cytochrome b complex

1987 • 405 citations

Cytochrome b ₅₅₈ : the Flavin-Binding Component of the Phagocyte NADPH Oxidase

1992 • 384 citations

Activation of NADPH-dependent superoxide production in a cell-free system by sodium dodecyl sulfate.

1985 • 356 citations

Cytochrome b-245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes

1992 • 351 citations

Primary structure and unique expression of the 22-kilodalton light chain of human neutrophil cytochrome b.

1988 • 317 citations

Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components.

1993 • 316 citations

Activation of human neutrophil nicotinamide adenine dinucleotide phosphate, reduced (triphosphopyridine nucleotide, reduced) oxidase by arachidonic acid in a cell-free system.

1985 • 315 citations

Molecular basis of chronic granulomatous disease [see comments]

1991 • 290 citations

A SYNDROME OF RECURRENT INFECTION AND INFILTRATION OF VISCERA BY PIGMENTED LIPID HISTIOCYTES

1957 • 251 citations

Association of a Ras-related protein with cytochrome b of human neutrophils

1989 • 248 citations

Molecular basis of chronic granulomatous disease [see comments]

1991 • 210 citations

Chronic Granulomatous Disease: The Solving of a Clinical Riddle at the Molecular Level

1993 • 185 citations

Mimicking of discontinuous epitopes by phage-displayed peptides, II. Selection of clones recognized by a protective monoclonal antibody against the Bordetella pertussis toxin from phage peptide libraries

1993 • 153 citations

Ultrastructural localization of cytochrome b in the membranes of resting and phagocytosing human granulocytes.

1990 • 145 citations

Evidence for a functional cytoplasmic domain of phagocyte oxidase cytochrome b558.

1990 • 134 citations

A structural model for the nucleotide binding domains of the flavocytochrome b_–245 β‐chain

1993 • 124 citations

Inhibition of Rap1A Binding to Cytochrome b ₅₅₈ of NADPH Oxidase by Phosphorylation of Rap1A

1991 • 120 citations

The initial steps in infection with coliphage M13

1964 • 117 citations

Topology of cytochrome b558 in neutrophil membrane analyzed by anti-peptide antibodies and proteolysis.

1992 • 110 citations

THE PROTEINS OF BACTERIOPHAGE M13

1969 • 107 citations

Recognition between a bacterial ribonuclease, barnase, and its natural inhibitor, barstar

1993 • 106 citations

Role of p67-phox SH3 domains in assembly of the NADPH oxidase system.

1994 • 106 citations

Molecular basis of oxidative damage by leukocytes

1993 • 96 citations

Human neutrophil cytochrome b contains multiple hemes. Evidence for heme associated with both subunits.

1992 • 95 citations

Adsorption protein of the bacteriophage fd: isolation, molecular properties, and location in the virus

1977 • 87 citations

The quaternary structure of the plasma membrane b-type cytochrome of human granulocytes

1988 • 74 citations

Superoxide production by cytochrome b₅₅₉

1994 • 66 citations

NADPH binding component of neutrophil superoxide-generating oxidase.

1986 • 61 citations

Two-stage selection of sequences from a random phage display library delineates both core residues and permitted structural range within an epitope

1994 • 56 citations

A Coat Protein of the Bacteriophage M13 Virion Participates in Membrane-Oriented Synthesis of DNA

1973 • 48 citations

Localization of the low-Mr subunit of cytochrome b558 in human blood phagocytes by immunoelectron microscopy

1990 • 48 citations

Identification of the NADPH-binding subunit of the respiratory burst oxidase.

1991 • 47 citations

Adsorption protein of bacteriophage fl: solubilization in deoxycholate and localization in the fl virion

1977 • 42 citations

NADPH-binding component of the superoxide-generating oxidase in unstimulated neutrophils and the neutrophils from the patients with chronic granulomatous disease

1987 • 41 citations

Extensive Contact between Gi2 and N-Formyl Peptide Receptor of Human Neutrophils: Mapping of Binding Sites Using Receptor-Mimetic Peptides

1995 • 35 citations