The Suppression of Aurora-A/STK15/BTAK Expression Enhances Chemosensitivity to Docetaxel in Human Esophageal Squamous Cell Carcinoma

Functional siRNAs and miRNAs Exhibit Strand Bias

2003 • 2,516 citations

Estimates of the worldwide mortality from 25 cancers in 1990

1999 • 1,494 citations

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1998 • 1,288 citations

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

1998 • 1,210 citations

Stable suppression of tumorigenicity by virus-mediated RNA interference

2002 • 1,147 citations

Aurora-kinase inhibitors as anticancer agents

2004 • 658 citations

AURORA-A amplification overrides the mitotic spindle assembly checkpoint, inducing resistance to Taxol

2003 • 615 citations

Centrosome defects and genetic instability in malignant tumors.

1998 • 583 citations

Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity

1998 • 515 citations

Results of a Nationwide Study on the Three-Field Lymph Node Dissection of Esophageal Cancer

1991 • 497 citations

Characterization of 21 newly established esophageal cancer cell lines

1992 • 490 citations

Suppression of BRAF(V599E) in human melanoma abrogates transformation.

2003 • 412 citations

A Small Interfering RNA Targeting Vascular Endothelial Growth Factor as Cancer Therapeutics

2004 • 377 citations

Aurora-A Kinase Maintains the Fidelity of Early and Late Mitotic Events in HeLa Cells

2003 • 361 citations

Centrosome defects can account for cellular and genetic changes that characterize prostate cancer progression.

2001 • 330 citations

Overexpression of oncogenic STK15/BTAK/Aurora A kinase in human pancreatic cancer.

2003 • 329 citations

Amplification/Overexpression of a Mitotic Kinase Gene in Human Bladder Cancer

2002 • 303 citations

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

2000 • 274 citations

Chromosomal instability and cytoskeletal defects in oral cancer cells

2000 • 269 citations

Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2–M transition

2004 • 265 citations

A phase II study of single-agent docetaxel in patients with metastatic esophageal cancer

2004 • 238 citations

RNA Interference Targeting Aurora Kinase A Suppresses Tumor Growth and Enhances the Taxane Chemosensitivity in Human Pancreatic Cancer Cells

2005 • 217 citations

The Clinical Significance of Aurora-A/STK15/BTAK Expression in Human Esophageal Squamous Cell Carcinoma

2005 • 124 citations

Correlation between centrosome abnormalities and chromosomal instability in human pancreatic cancer cells

2001 • 103 citations

Centrosome abnormalities in human carcinomas of the gallbladder and intrahepatic and extrahepatic bile ducts

2000 • 76 citations

Progress in the Development of Selective Inhibitors of Aurora Kinases

2005 • 75 citations

STK15/Aurora‐A expression in primary breast tumors is correlated with nuclear grade but not with prognosis

2003 • 74 citations

Nonrandom Chromosomal Imbalances in Esophageal Squamous Cell Carcinoma Cell Lines: Possible Involvement of the ATF3 and CENPF Genes in the 1q32 Amplicon

2000 • 73 citations

Phase II trial of irinotecan plus docetaxel in cisplatin-pretreated relapsed or refractory oesophageal cancer

2003 • 72 citations

Inhibition of Cyclooxygenase (COX)-2 Expression by Tet-Inducible COX-2 Antisense cDNA in Hormone-Refractory Prostate Cancer Significantly Slows Tumor Growth and Improves Efficacy of Chemotherapeutic Drugs

2004 • 66 citations

Aurora2/BTAK/STK15 is involved in cell cycle checkpoint and cell survival of aggressive non‐Hodgkin's lymphoma

2003 • 62 citations

Preparation and characterization of a human aurora-A kinase monoclonal antibody.

2003 • 27 citations

Aurora-A Overexpression Leads to Override of the Microtubule-Kinetochore Attachment Checkpoint

2003 • 20 citations