Centrosome abnormalities in human carcinomas of the gallbladder and intrahepatic and extrahepatic bile ducts

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1998 • 1,288 citations

Abnormal Centrosome Amplification in the Absence of p53

1996 • 802 citations

Centrosome defects and genetic instability in malignant tumors.

1998 • 583 citations

Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity

1998 • 515 citations

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression

1999 • 284 citations

Genomic instability and apoptosis are frequent in p53 deficient young mice

1997 • 197 citations

Supernumerary centrosomes and cancer: Boveri's hypothesis resurrected

1998 • 156 citations

Centrosome abnormalities in pancreatic ductal carcinoma.

1999 • 129 citations

Amorphous no longer: the centrosome comes into focus

1999 • 128 citations

p53 Protein overexpression in gallbladder carcinoma and its precursor lesions: An immunohistochemical study

1996 • 121 citations

Proliferative potential and K-ras mutation in epithelial hyperplasia of the gallbladder in patients with anomalous pancreaticobiliary ductal union

1998 • 103 citations

K‐ ras codon 12 mutations in biliary tract tumors detected by polymerase chain reaction denaturing gradient gel electrophoresis

1994 • 96 citations

Centrosome amplification as a possible mechanism for numerical chromosome aberrations in cerebral primitive neuroectodermal tumors with TP53 mutations

1998 • 91 citations

K-ras gene mutation in gall bladder carcinomas and dysplasia.

1996 • 88 citations

APC, K‐ras codon 12 mutations and p53 gene expression in carcinoma and adenoma of the gall‐bladder suggest two genetic pathways in gall‐bladder carcinogenesis

1996 • 80 citations

K-ras codon 12 mutations in biliary tract tumors detected by polymerase chain reaction denaturing gradient gel electrophoresis

1994 • 74 citations

Expression of p53 in adenocarcinoma of the gallbladder and bile ducts

1996 • 73 citations

p53 protein expression and prognosis in gallbladder carcinoma and premalignant lesions.

1996 • 57 citations

p53 protein immunoreactivity in cancers of the gallbladder, extrahepatic bile ducts and ampulla of Vater

1995 • 39 citations

Adenocarcinoma of the extrahepatic biliary tree.

1985 • 33 citations

Activation of telomerase and its diagnostic application in biopsy specimens from biliary tract neoplasms

1999 • 27 citations

Detection of Ras Oncogene Point Mutations and Simultaneous Proliferative Fraction Estimation in Gallbladder Cancer

1996 • 19 citations

Immunohistochemical detection of the nm23-H1 protein in gallbladder and biliary tract tumours

1995 • 7 citations