Chromosomal instability and cytoskeletal defects in oral cancer cells

A simple technique for demonstrating centromeric heterochromatin

1972 • 4,206 citations

Genetic instabilities in human cancers

1998 • 4,165 citations

Cell Cycle Checkpoints: Preventing an Identity Crisis

1996 • 2,056 citations

The chromosomes in human cancer and leukemia

1990 • 1,780 citations

How Cells Get the Right Chromosomes

1997 • 625 citations

A Complex of NuMA and Cytoplasmic Dynein Is Essential for Mitotic Spindle Assembly

1996 • 565 citations

The pericentriolar material in Chinese hamster ovary cells nucleates microtubule formation

1977 • 416 citations

Expression of Fragile Sites Triggers Intrachromosomal Mammalian Gene Amplification and Sets Boundaries to Early Amplicons

1997 • 399 citations

Hidden chromosome abnormalities in haematological malignancies detected by multicolour spectral karyotyping

1997 • 360 citations

Telomeres and telomerase in aging and cancer

1995 • 328 citations

Taxol-induced microtubule asters in mitotic extracts of Xenopus eggs: requirement for phosphorylated factors and cytoplasmic dynein.

1991 • 300 citations

Biology, cytogenetics, and sensitivity to immunological effector cells of new head and neck squamous cell carcinoma lines.

1989 • 254 citations

Human telomeres: fusion and interstitial sites

1989 • 248 citations

Primary structure of NuMA, an intranuclear protein that defines a novel pathway for segregation of proteins at mitosis.

1992 • 215 citations

Amplification of cyclin D1 in squamous cell carcinoma of the head and neck and the prognostic value of chromosomal abnormalities and cyclin D1 overexpression

1997 • 210 citations

Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells.

1993 • 194 citations

Immunofluorescent staining of kinetochores in micronuclei: A new assay for the detection of aneuploidy

1988 • 179 citations

Distinctive chromosomal structures are formed very early in the amplification of CAD genes in Syrian hamster cells

1990 • 136 citations

Formation of the tetraploid intermediate is associated with the development of cells with more than four centrioles in the elastase-simian virus 40 tumor antigen transgenic mouse model of pancreatic cancer.

1991 • 133 citations

A Nonerythroid Isoform of Protein 4.1R Interacts with the Nuclear Mitotic Apparatus (NuMA) Protein

1999 • 125 citations

Centriole distribution during tripolar mitosis in Chinese hamster ovary cells.

1984 • 112 citations

SPONTANEOUS ALTERATIONS IN CHROMOSOME SIZE AND FORM IN ZEA MAYS

1941 • 108 citations

Fusions near telomeres occur very early in the amplification of CAD genes in Syrian hamster cells.

1992 • 108 citations

Chromosome elimination in micronuclei: a common cause of hypoploidy.

1988 • 107 citations

The nuclear-mitotic apparatus protein is important in the establishment and maintenance of the bipolar mitotic spindle apparatus.

1992 • 105 citations

NuMA is a component of an insoluble matrix at mitotic spindle poles

1999 • 81 citations

Dicentric chromosomes and the inactivation of the centromere

1986 • 79 citations

Localized formation of micronuclei in the oral mucosa and tobacco‐specific nitrosamines in the saliva of “reverse” smokers, khaini‐tobacco chewers and gudakhu users

1992 • 76 citations

Visualization of INT2 and HST1 Amplification in oral squamous cell carcinomas

1995 • 71 citations

FISH characterization of head and neck carcinomas reveals that amplification of band 11q13 is associated with deletion of distal 11q.

1998 • 66 citations

FISH characterization of head and neck carcinomas reveals that amplification of band 11q13 is associated with deletion of distal 11q

1998 • 55 citations

Genome stability: Keeping the centrosome cycle on track

1996 • 51 citations

Telomeric fusions in cultured human fibroblasts as a source of genomic instability

1997 • 45 citations

Telomeric associations evolving to ring chromosomes in a recurrent pleomorphic xanthoastrocytoma

1992 • 44 citations

Micronuclei, a biomarker for chemoprevention trials: Results of a randomized study in oral pre‐malignancy

1994 • 42 citations

Novel biomarkers of genetic damage in humans: Use of fluorescence in situ hybridization to detect aneuploidy and micronuclei in exfoliated cells

1993 • 41 citations

p53-dependent growth arrest of REF52 cells containing newly amplified DNA.

1995 • 37 citations

Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles.

1996 • 33 citations

Cytogenetic and fluorescence in situ hybridization characterization of chromosome 1 rearrangements in head and neck carcinomas delineate a target region for deletions within 1p11-1p13.

1998 • 25 citations

Ring chromosome 12 resulting from nonrandom telomeric associations with the short arm of chromosome 15 in a cerebellar astrocytoma

1993 • 22 citations

Genetic instability and cancer.

1998 • 16 citations

Cytogenetics In Head And Neck Cancer

1992 • 14 citations

Structural instability of a transmissible end-to-end dicentric chromosome in a xeroderma pigmentosum fibroblast clone

1995 • 8 citations

Nuclear projections and latent centromeres in primary cultures and established cell lines.

1978 • 7 citations