NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice.

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

Neuron‐glia relationship during granule cell migration in developing cerebellar cortex. A Golgi and electonmicroscopic study in Macacus rhesus

1971 • 1,334 citations

Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice

1992 • 1,138 citations

Inactivation of the N-CAM gene in mice results in size reduction of the olfactory bulb and deficits in spatial learning

1994 • 1,010 citations

Extracellular Matrix Molecules and their Receptors: Functions in Neural Development

1991 • 726 citations

Association between the PDGF receptor and members of the src family of tyrosine kinases

1990 • 650 citations

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor.

1990 • 647 citations

Kinetics of homophilic binding by embryonic and adult forms of the neural cell adhesion molecule.

1983 • 635 citations

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1992 • 574 citations

Peptides and Protein Phosphorylation

2018 • 525 citations

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

1992 • 514 citations

Genetic deletion of a neural cell adhesion molecule variant (N-CAM-180) produces distinct defects in the central nervous system

1993 • 476 citations

Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets.

1991 • 415 citations

Development of neuronal polarity: GAP-43 distinguishes axonal from dendritic growth cones

1988 • 413 citations

Neural cell adhesion molecules influence second messenger systems

1989 • 387 citations

Guidance of optic axons in vivo by a preformed adhesive pathway on neuroepithelial endfeet

1984 • 386 citations

Initial events of myelination involve Fyn tyrosine kinase signalling

1994 • 383 citations

Genetic analysis of a drosophila neural cell adhesion molecule: Interaction of fasciclin I and abelson tyrosine kinase mutations

1990 • 340 citations

Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene

1985 • 306 citations

The neural cell adhesion molecule N-CAM enhances L1-dependent cell-cell interactions.

1990 • 305 citations

Neurite outgrowth in response to transfected N-CAM changes during development and is modulated by polysialic acid

1990 • 299 citations

pp60c-src is developmentally regulated in the neural retina

1984 • 299 citations

Studies of adhesion molecules mediating interactions between cells of peripheral nervous system indicate a major role for L1 in mediating sensory neuron growth on Schwann cells in culture.

1988 • 288 citations

Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1

1994 • 276 citations

Functional characterization of chondroitin sulfate proteoglycans of brain: interactions with neurons and neural cell adhesion molecules.

1993 • 268 citations

Molecular Mechanisms of Axon Growth and Guidance

1991 • 263 citations

A threshold effect of the major isoforms of NCAM on neurite outgrowth

1990 • 260 citations

Neurite outgrowth on muscle cell surfaces involves extracellular matrix receptors as well as Ca2+-dependent and -independent cell adhesion molecules.

1987 • 233 citations

Osteoclasts express high levels of pp60c-src in association with intracellular membranes.

1992 • 221 citations

Immunoelectron microscopic localization of the neural cell adhesion molecules L1 and N-CAM during postnatal development of the mouse cerebellum.

1987 • 215 citations

Fate of GAP-43 in ascending spinal axons of DRG neurons after peripheral nerve injury: delayed accumulation and correlation with regenerative potential

1991 • 211 citations

Neural cell adhesion molecules modulate tyrosine phosphorylation of tubulin in nerve growth cone membranes

1992 • 197 citations

c-src gene product in developing rat brain is enriched in nerve growth cone membranes.

1988 • 193 citations

Recombinant myelin-associated glycoprotein confers neural adhesion and neurite outgrowth function

1989 • 190 citations

Neurite outgrowth in response to transfected N-CAM and N-cadherin reveals fundamental differences in neuronal responsiveness to CAMs

1991 • 178 citations

The cellular neurobiology of neuronal development: The cerebellar granule cell

1988 • 174 citations

Expression of a novel form of the fyn proto-oncogene in hematopoietic cells.

1989 • 174 citations

Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF

1994 • 163 citations

Biosynthesis, membrane association, and release of N-CAM-120, a phosphatidylinositol-linked form of the neural cell adhesion molecule.

1987 • 154 citations

Identification of a heparin binding domain of the neural cell adhesion molecule N-CAM using synthetic peptides

1989 • 151 citations

pp60c-src in the developing cerebellum.

1985 • 147 citations

The VASE exon downregulates the neurite growth-promoting activity of NCAM 140

1992 • 145 citations

Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transduction.

1993 • 138 citations

Tubulin is phosphorylated at tyrosine by pp60c-src in nerve growth cone membranes.

1990 • 137 citations

Alternatively spliced mRNAs code for different polypeptide chains of the chicken neural cell adhesion molecule (N-CAM).

1986 • 122 citations

Cell adhesion molecules, second messengers and axonal growth

1992 • 116 citations

Expression of the unique NCAM VASE exon is independently regulated in distinct tissues during development.

1990 • 110 citations

Cell Type‐specific Effects of the Neural Adhesion Molecules L1 and N‐CAM on Diverse Second Messenger Systems

1992 • 106 citations

Tyrosine phosphorylation in early embryonic growth cones

1993 • 102 citations

Direct activation of second messenger pathways mimics cell adhesion molecule-dependent neurite outgrowth.

1992 • 95 citations

At Least 27 Alternatively Spliced Forms of the Neural Cell Adhesion Molecule mRNA Are Expressed during Rat Heart Development

1991 • 88 citations

Inhibition of tyrosine phosphorylation potentiates substrate‐induced neurite growth

1992 • 81 citations

p59fyn in rat brain is localized in developing axonal tracts and subpopulations of adult neurons and glia.

1993 • 74 citations

Regional localization of Fyn in adult brain; studies with mice in which fyn gene was replaced by lacZ.

1993 • 70 citations

Nonreceptor Protein Tyrosine Kinases Associated with Neuronal Development

1992 • 70 citations

Molecular cloning of two abundant protein tyrosine kinases in Torpedo electric organ that associate with the acetylcholine receptor.

1993 • 61 citations

Alterations in the Xenopus retinotectal projection by antibodies to Xenopus N-CAM

1988 • 60 citations

Differentiation of PC12 cells with v‐src: Comparison with nerve growth factor

1989 • 55 citations

Increased Neurite Outgrowth Induced by Inhibition of Protein Tyrosine Kinase Activity in PC12 Pheochromocytoma Cells

1993 • 55 citations

Characterization of isolated mouse cerebellar cell populations in vitro

1981 • 53 citations

Differential roles of multiple adhesion molecules in cell migration: Granule cell migration in cerebellum

1990 • 51 citations

Evidence for heterophilic adhesion of embryonic retinal cells and neuroblastoma cells to substratum-adsorbed NCAM

1992 • 43 citations

Localization of p62c-yes protein in mammalian neural tissues.

1991 • 43 citations

Axon growth is enhanced by NCAM lacking the VASE exon when expressed in either the growth substrate or the growing axon

1993 • 40 citations

Increased expression of pp60^c‐src protein‐tyrosine kinase during peripheral nerve regeneration

1991 • 39 citations

pp60^c-src in the Developing Cerebellum

1985 • 33 citations

Neurite extension and protein tyrosine phosphorylation elicited by inducible expression of the v-src oncogene in a PC12 cell line*1

1991 • 30 citations

Molecular Association of the Neural Adhesion Molecules L1 and N‐CAM in the Surface Membrane of Neuroblastoma Cells is Shown by Chemical Cross‐linking

1991 • 29 citations

Altered expression of pp60^c‐src induced by peripheral nerve injury

1992 • 19 citations

Developmental regulation of protein tyrosine phosphorylation in rat brain

1988 • 18 citations

v‐src genes stimulate neurite outgrowth in pheochromocytoma (PC12) variants unresponsive to neurotrophic factors

1989 • 16 citations

Characterization of NCAM diversity in cultured neurons

1993 • 11 citations

pp59^fyn and pp62^c‐yes are enriched in SH‐SY5Y neuroblastoma growth cones but do not associate to the 38 kDa protein which complexes with pp60^{c src} and pp60^c‐srcN

1993 • 8 citations