Naturally Occurring Transposable Elements Disrupt hsp70 Promoter Function in Drosophila melanogaster

Mobile Elements: Drivers of Genome Evolution

2004 • 1,833 citations

A Single P450 Allele Associated with Insecticide Resistance in Drosophila

2002 • 829 citations

Structures of P transposable elements and their sites of insertion and excision in the Drosophila melanogaster genome

1983 • 794 citations

Genome evolution of wild barley ( Hordeum spontaneum ) by BARE -1 retrotransposon dynamics in response to sharp microclimatic divergence

2000 • 596 citations

Protein traffic on the heat shock promoter: Parking, stalling, and trucking along

1993 • 507 citations

Germline Transformation Used to Define Key Features of Heat-Shock Response Elements

1988 • 451 citations

DNA position-specific repression of transcription by a Drosophila zinc finger protein.

1992 • 418 citations

Abundant Raw Material for Cis-Regulatory Evolution in Humans

2002 • 377 citations

Deleterious consequences of Hsp70 overexpression in Drosphilla melanogaster larvae

1997 • 318 citations

Drosophila melanogaster mutations suppressible by the suppressor of Hairy-wing are insertions of a 7.3-kilobase mobile element.

1983 • 302 citations

Genetic variation in thermal tolerance among natural populations of Drosophila buzzatii: down regulation of Hsp70 expression and variation in heat stress resistance traits

2001 • 244 citations

Strong selective sweep associated with a transposon insertion in Drosophila simulans

2004 • 237 citations

Effect of EngineeringHsp70Copy Number on Hsp70 Expression and Tolerance of Ecologically Relevant Heat Shock in Larvae and Pupae ofDrosophila Melanogaster

1996 • 222 citations

The solution structure of a specific GAGA factor–DNA complex reveals a modular binding mode

1997 • 219 citations

KP elements repress P-induced hybrid dysgenesis in Drosophila melanogaster.

1987 • 213 citations

NATURAL VARIATION IN THE EXPRESSION OF THE HEAT‐SHOCK PROTEIN HSP70 IN A POPULATION OF DROSOPHILA MELANOGASTER AND ITS CORRELATION WITH TOLERANCE OF ECOLOGICALLY RELEVANT THERMAL STRESS

1997 • 195 citations

DNA sequence requirements for generating paused polymerase at the start of hsp70.

1992 • 188 citations

Natural thermal stress and heat‐shock protein expression in Drosophila larvae and pupae

1997 • 167 citations

HSF access to heat shock elements in vivo depends critically on promoter architecture defined by GAGA factor, TFIID, and RNA polymerase II binding sites.

1995 • 131 citations

EXPERIMENTAL EVOLUTION OF HSP70 EXPRESSION AND THERMOTOLERANCE IN DROSOPHILA MELANOGASTER

1999 • 129 citations

Genetic evidence for adaptation-driven incipient speciation ofDrosophilamelanogasteralong a microclimatic contrast in “Evolution Canyon,” Israel

2001 • 125 citations

RNA polymerase II pauses at the 5' end of the transcriptionally induced Drosophila hsp70 gene.

1991 • 124 citations

A DROSOPHILA MELANOGASTER Strain From Sub-Equatorial Africa Has Exceptional Thermotolerance But Decreased Hsp70 Expression

2001 • 123 citations

Dynamics of potentiation and activation: GAGA factor and its role in heat shock gene regulation

1997 • 112 citations

Response To Natural And Laboratory Selection At The Drosophila Hsp70 Genes

2002 • 100 citations

Modification of Heat-Shock Gene Expression in Drosophila melanogaster Populations via Transposable Elements

2003 • 91 citations

Cooperative and Competitive Protein Interactions at the Hsp70 Promoter

1997 • 88 citations

Repression of hybrid dysgenesis in Drosophila melanogaster by individual naturally occurring P elements.

1993 • 74 citations

High-resolution mapping of DNase I-hypersensitive sites of Drosophila heat shock genes in Drosophila melanogaster and Saccharomyces cerevisiae.

1984 • 62 citations

Replacement of Fab-7 by the gypsy or scs Insulator Disrupts Long-Distance Regulatory Interactions in the Abd-B Gene of the Bithorax Complex

2001 • 59 citations

Molecular Architecture of the hsp70 Promoter after Deletion of the TATA Box or the Upstream Regulation Region

1997 • 56 citations

S-element Insertions Are Associated with the Evolution of the Hsp70 Genes in Drosophila melanogaster

2002 • 56 citations

Experimental Evolution of Hsp70 Expression and Thermotolerance in Drosophila melanogaster

1999 • 50 citations

Analyses of Promoter-Proximal Pausing by RNA Polymerase II on the hsp70 Heat Shock Gene Promoter in a Drosophila Nuclear Extract

1996 • 42 citations

Retrotransposon-Gene Associations Are Widespread Among D. melanogaster Populations

2004 • 40 citations

Cooperative binding of heat shock transcription factor to the Hsp70 promoter in vivo and in vitro.

1994 • 39 citations

Evolvability of Hsp70 Expression under Artificial Selection for Inducible Thermotolerance in Independent Populations ofDrosophila melanogaster

2002 • 20 citations