Cooperative and Competitive Protein Interactions at the Hsp70 Promoter

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

1980 • 1,114 citations

ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor

1994 • 662 citations

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

1990 • 620 citations

GAL4 activates transcription in Drosophila

1988 • 521 citations

Stress-induced oligomerization and chromosomal relocalization of heat-shock factor

1991 • 391 citations

Binding of general transcription factor TFIIB to an acidic activating region

1991 • 377 citations

Reduced binding of TFIID to transcriptionally compromised mutants of VP16

1991 • 362 citations

In vivo transcriptional pausing and cap formation on three Drosophila heat shock genes.

1993 • 361 citations

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53.

1994 • 355 citations

GAL4 activates gene expression in mammalian cells

1988 • 355 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II

1989 • 304 citations

Control of formation of two distinct classes of RNA polymerase II elongation complexes.

1992 • 295 citations

Contact with a component of the polymerase II holoenzyme suffices for gene activation

1995 • 262 citations

TBP-TAF complexes: selectivity factors for eukaryotic transcription

1994 • 250 citations

Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II.

1989 • 250 citations

Transcription elongation and eukaryotic gene regulation.

1990 • 227 citations

Interaction between an acidic activator and transcription factor TFIIB is required for transcriptional activation

1993 • 225 citations

Specific interaction between the nonphosphorylated form of RNA polymerase II and the TATA-binding protein

1992 • 219 citations

Connecting a promoter-bound protein to TBP bypasses the need for a transcriptional activation domain

1995 • 188 citations

DNA sequence requirements for generating paused polymerase at the start of hsp70.

1992 • 188 citations

Stimulation of RNA polymerase II transcription initiation by recruitment of TBP in vivo

1995 • 161 citations

Promoter melting and TFIID complexes on Drosophila genes in vivo.

1992 • 155 citations

HSF access to heat shock elements in vivo depends critically on promoter architecture defined by GAGA factor, TFIID, and RNA polymerase II binding sites.

1995 • 131 citations

RNA polymerase II transcription factor SIII. I. Identification, purification, and properties.

1993 • 127 citations

RNA polymerase II pauses at the 5' end of the transcriptionally induced Drosophila hsp70 gene.

1991 • 124 citations

Functional differences between yeast and human TFIID are localized to the highly conserved region

1991 • 121 citations

Effects of activation-defective TBP mutations on transcription initiation in yeast

1994 • 110 citations

Initiation of transcription by RNA polymerase II is limited by melting of the promoter DNA in the region immediately upstream of the initiation site.

1994 • 110 citations

The DNA-Binding Properties of Two Heat Shock Factors, HSF1 and HSF3, Are Induced in the Avian Erythroblast Cell Line HD6

1995 • 109 citations

Recruiting TATA-Binding Protein to a Promoter: Transcriptional Activation without an Upstream Activator

1995 • 108 citations

Fractionation of transcription factors for RNA polymerase II from Drosophila Kc cell nuclear extracts.

1987 • 103 citations

Protein-protein interactions in eukaryotic transcription initiation: structure of the preinitiation complex.

1996 • 97 citations

A highly conserved domain of TFIID displays species specificity in vivo

1991 • 97 citations

Distribution of GAGA protein on Drosophila genes in vivo.

1995 • 92 citations

Transcriptional Activation Domain of the Herpesvirus Protein VP16 Becomes Conformationally Constrained upon Interaction with Basal Transcription Factors

1996 • 89 citations

Optimal heat-induced expression of the Drosophila hsp26 gene requires a promoter sequence containing (CT) · (GA) repeats

1990 • 87 citations

The C-terminal region of Drosophila heat shock factor (HSF) contains a constitutively functional transactivation domain

1996 • 70 citations

Mutations on the DNA-Binding Surface of TATA-Binding Protein Can Specifically Impair the Response to Acidic Activators In Vivo

1995 • 58 citations

Multiple, compensatory regulatory elements specify spermatocyte-specific expression of the Drosophila melanogaster hsp26 gene.

1990 • 58 citations

The upstream activator CTF/NF1 and RNA polymerase II share a common element involved in transcriptional activation

1994 • 58 citations

A Highly Conserved Domain of RNA Polymerase II Shares a Functional Element with Acidic Activation Domains of Upstream Transcription Factors

1994 • 36 citations