Analyses of Promoter-Proximal Pausing by RNA Polymerase II on the hsp70 Heat Shock Gene Promoter in a Drosophila Nuclear Extract

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

The RNA polymerase II molecule at the 5′ end of the uninduced hsp70 gene of D. melanogaster is transcriptionally engaged

1988 • 662 citations

ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor

1994 • 662 citations

Protein traffic on the heat shock promoter: Parking, stalling, and trucking along

1993 • 507 citations

Transcription factors that activate the Ultrabithorax promoter in developmentally staged extracts

1988 • 454 citations

The Organization of the Histone Genes in Drosophila melanogaster: Functional and Evolutionary Implications

1978 • 419 citations

Purification and Properties of Drosophila Heat Shock Activator Protein

1987 • 388 citations

Sequence-Specific Antirepression of Histone H1-Mediated Inhibition of Basal RNA Polymerase II Transcription

1991 • 378 citations

In vivo transcriptional pausing and cap formation on three Drosophila heat shock genes.

1993 • 361 citations

Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation

1994 • 325 citations

Eukaryotic activators function during multiple steps of preinitiation complex assembly

1993 • 311 citations

Transcription mechanisms and regulation

1994 • 299 citations

Control of formation of two distinct classes of RNA polymerase II elongation complexes.

1992 • 295 citations

Binding of TAFs to core elements directs promoter selectivity by RNA polymerase II

1995 • 290 citations

Promoter-proximal pausing of RNA polymerase II defines a general rate-limiting step after transcription initiation.

1995 • 220 citations

Polymerase II Promoter Activation: Closed Complex Formation and ATP-Driven Start Site Opening

1992 • 220 citations

Specific interaction between the nonphosphorylated form of RNA polymerase II and the TATA-binding protein

1992 • 219 citations

TFIID sequence recognition of the initiator and sequences farther downstream in Drosophila class II genes.

1994 • 207 citations

Drosophila Nuclear Proteins Bind to Regions of Alternating C and T Residues in Gene Promoters

1989 • 200 citations

The C-terminal repeat domain of RNA polymerase II largest subunit is essential in vivo but is not required for accurate transcription initiation in vitro.

1988 • 190 citations

DNA sequence requirements for generating paused polymerase at the start of hsp70.

1992 • 188 citations

Postinitiation Transcriptional Control in Drosophila melanogaster

1990 • 177 citations

Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: correlations with gene activity and transcript processing.

1993 • 175 citations

Rapid changes in Drosophila transcription after an instantaneous heat shock.

1993 • 164 citations

The acidic activator GAL4-AH can stimulate polymerase II transcription by promoting assembly of a closed complex requiring TFIID and TFIIA.

1992 • 160 citations

Promoter melting and TFIID complexes on Drosophila genes in vivo.

1992 • 155 citations

Assembly and disassembly of the Drosophila RNA polymerase II complex during transcription.

1990 • 134 citations

Chromatin remodeling by GAGA factor and heat shock factor at the hypersensitive Drosophila hsp26 promoter in vitro.

1995 • 121 citations

Regulation of transcriptional elongation by RNA polymerase II

1995 • 111 citations

α-amanitin-resistant D. melanogaster with an altered RNA polymerase II

1979 • 106 citations

Fractionation of transcription factors for RNA polymerase II from Drosophila Kc cell nuclear extracts.

1987 • 103 citations

Distribution of GAGA protein on Drosophila genes in vivo.

1995 • 92 citations

Short Transcripts of the Ternary Complex Provide Insight into RNA Polymerase II Elongational Pausing

1995 • 73 citations

Common mechanisms for the control of eukaryotic transcriptional elongation

1993 • 71 citations

lac repressor acts by modifying the initial transcribing complex so that it cannot leave the promoter

1991 • 71 citations

Transcription factor TFIID recognizes DNA sequences downstream of the TATA element in the Hsp70 heat shock gene.

1993 • 51 citations

Dual regulation of theDrosophillahsp26 promoterin vitro

1995 • 48 citations

Protein/DNA crosslinking of a TFIID complex reveals novel interactions downstream of the transcription start

1994 • 46 citations

The carboxyl-terminal repeat domain of RNA polymerase II is not required for transcription factor Sp1 to function in vitro.

1990 • 44 citations

A Highly Conserved Domain of RNA Polymerase II Shares a Functional Element with Acidic Activation Domains of Upstream Transcription Factors

1994 • 36 citations

Polymerase processivity and termination on Drosophila heat shock genes.

1993 • 32 citations

Abortive initiation is increased only for the weakest members of a set of down mutants of the adenovirus 2 major late promoter.

1991 • 26 citations

Genomic footprinting of thehsp70and histone H3 promoters inDrosophilaembryos reveals novel protein-DNA interactions

1995 • 16 citations

Protein-DNA Cross-Linking Reveals Dramatic Variation in RNA Polymerase II Density on Different Histone Repeats of Drosophila melanogaster

1987 • 16 citations