How the parasitic bacterium Legionella pneumophila modifies its phagosome and transforms it into rough ER: implications for conversion of plasma membrane to the ER membrane

Functional rafts in cell membranes

1997 • 9,471 citations

Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)

1976 • 2,468 citations

Common themes in microbial pathogenicity revisited

1997 • 1,370 citations

Caveolar endocytosis of simian virus 40 reveals a new two-step vesicular-transport pathway to the ER

2001 • 1,236 citations

How Cells Handle Cholesterol

2000 • 1,230 citations

Cholesterol and the Golgi Apparatus

1993 • 819 citations

Common themes in microbial pathogenicity revisited.

1997 • 782 citations

Conjugative Transfer by the Virulence System of Legionella pneumophila

1998 • 709 citations

Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited.

1995 • 680 citations

Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes.

1983 • 644 citations

Essential Role for Cholesterol in Entry of Mycobacteria into Macrophages

2000 • 610 citations

A Coat Protein on Phagosomes Involved in the Intracellular Survival of Mycobacteria

1999 • 573 citations

Association of Legionella pneumophila with the macrophage endoplasmic reticulum

1995 • 556 citations

Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome

1998 • 530 citations

Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells

2000 • 485 citations

The plant ER: a dynamic organelle composed of a large number of discrete functional domains

1997 • 458 citations

Brucella abortus Transits through the Autophagic Pathway and Replicates in the Endoplasmic Reticulum of Nonprofessional Phagocytes

1998 • 408 citations

Differential interaction with endocytic and exocytic pathways distinguish parasitophorous vacuoles of Coxiella burnetii and Chlamydia trachomatis

1996 • 394 citations

Legionella PneumophilaPathogenesis: A Fateful Journey from Amoebae to Macrophages

2000 • 378 citations

Expression of Legionella pneumophila Virulence Traits in Response to Growth Conditions

1998 • 361 citations

Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake

1998 • 360 citations

Autophagy, Cytoplasm-to-Vacuole Targeting Pathway, and Pexophagy in Yeast and Mammalian Cells

2000 • 359 citations

Identification of Legionella pneumophila genes required for growth within and killing of human macrophages

1993 • 357 citations

IpaB of Shigella flexneri causes entry into epithelial cells and escape from the phagocytic vacuole.

1992 • 316 citations

Association of host cell endoplasmic reticulum and mitochondria with the Toxoplasma gondii parasitophorous vacuole membrane: A high affinity interaction

1997 • 314 citations

Combined influence of cholesterol and synthetic amphiphillic peptides upon bilayer thickness in model membranes

1992 • 309 citations

Endocytosis of simian virus 40 into the endoplasmic reticulum.

1989 • 257 citations

Substructure of freeze-substituted plasmodesmata

1992 • 252 citations

Altered intracellular targeting properties associated with mutations in the Legionella pneumophila dotA gene

1994 • 248 citations

Similarity of junctions between plasma membranes and endoplasmic reticulum in muscle and neurons.

1976 • 222 citations

From protozoa to mammalian cells: a new paradigm in the life cycle of intracellular bacterial pathogens

2000 • 221 citations

Identification of Linked Legionella pneumophila Genes Essential for Intracellular Growth and Evasion of the Endocytic Pathway

1998 • 201 citations

Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth

2000 • 173 citations

Characterization of a new region required for macrophage killing by Legionella pneumophila

1997 • 166 citations

Transformation of Leukocytes byTheileria parvaandT. annulata

1999 • 159 citations

Structural features of the lateral walls in mammalian cochlear outer hair cells

1991 • 157 citations

Micro- and Nanomechanics of the Cochlear Outer Hair Cell

2001 • 151 citations

Endoplasmic Reticulum Forms a Dynamic Continuum for Lipid Diffusion between Contiguous Soybean Root Cells.

1993 • 129 citations

High pressure freezing of intact plant tissues. Evaluation and characterization of novel features of the endoplasmic reticulum and associated membrane systems.

1988 • 125 citations

Early Events in Phagosome Establishment Are Required for Intracellular Survival of Legionella pneumophila

1998 • 124 citations

The structure of plasmodesmata as revealed by plasmolysis, detergent extraction, and protease digestion.

1991 • 123 citations

Identification and Subcellular Localization of the Legionella pneumophila IcmX Protein: a Factor Essential for Establishment of a Replicative Organelle in Eukaryotic Host Cells

2000 • 93 citations

Intermembrane Molecular Contacts by Polymyxin B Mediate Exchange of Phospholipids

1996 • 80 citations

Characterization of mechanisms for transfer of cholesterol between human erythrocytes and plasma

1977 • 66 citations

Heterogeneity in intracellular replication and cytopathogenicity of Legionella pneumophila and Legionella micdadei in mammalian and protozoan cells

1999 • 60 citations

Identification of the Aspartate-β-Semialdehyde Dehydrogenase Gene of Legionella pneumophila and Characterization of a Null Mutant

1998 • 59 citations

The Cell Biology of Listeria monocytogenes Infection (Escape from a Vacuole)

1994 • 55 citations

Endoplasmic Reticulum Forms a Dynamic Continuum for Lipid Diffusion between Contiguous Soybean Root Cells

1993 • 53 citations

Interactions between Toxoplasma gondii and its mammalian host cells

1993 • 50 citations

Specificity for the Exchange of Phospholipids Through Polymyxin B Mediated Intermembrane Molecular Contacts

1996 • 42 citations

Characterization of the outer hair cell's lateral wall membranes

1993 • 41 citations

Trypanosoma cruzi: mechanisms for entry into host cells

1993 • 28 citations

Movement of plasma-membrane sterols to the endoplasmic reticulum in cultured cells

1987 • 26 citations

Essential Role for the Legionella pneumophila Rep Helicase Homologue in Intracellular Infection of Mammalian Cells

2000 • 20 citations

Localization of Legionella bacteria within ribosome-studded phagosomes is not restricted to Legionella pneumophila

2000 • 14 citations