Early Events in Phagosome Establishment Are Required for Intracellular Survival of Legionella pneumophila

Establishment and characterization of a human histiocytic lymphoma cell line (U‐937)

1976 • 2,468 citations

Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining.

1975 • 1,734 citations

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

1978 • 1,624 citations

The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes.

1983 • 704 citations

Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus

1994 • 676 citations

Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes.

1983 • 644 citations

Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila

1993 • 633 citations

Association of Legionella pneumophila with the macrophage endoplasmic reticulum

1995 • 556 citations

Phagosome-lysosome interactions in cultured macrophages infected with virulent tubercle bacilli. Reversal of the usual nonfusion pattern and observations on bacterial survival.

1975 • 528 citations

THE INTERACTION BETWEEN TOXOPLASMA GONDII AND MAMMALIAN CELLS

1972 • 527 citations

Statistics with applications to the biological and health sciences

1970 • 491 citations

Toxoplasma gondii : Fusion Competence of Parasitophorous Vacuoles in Fc Receptor-Transfected Fibroblasts

1990 • 446 citations

Differential interaction with endocytic and exocytic pathways distinguish parasitophorous vacuoles of Coxiella burnetii and Chlamydia trachomatis

1996 • 394 citations

Legionella pneumophila inhibits acidification of its phagosome in human monocytes.

1984 • 384 citations

Growth of Legionella pneumophila in Acanthamoeba castellanii enhances invasion

1994 • 366 citations

Identification of Legionella pneumophila genes required for growth within and killing of human macrophages

1993 • 357 citations

Phagocytosis of the legionnaires' disease bacterium (legionella pneumophila) occurs by a novel mechanism: Engulfment within a Pseudopod coil

1984 • 317 citations

Identification of a Legionella pneumophila locus required for intracellular multiplication in human macrophages.

1992 • 310 citations

Primary isolation media for Legionnaires disease bacterium

1978 • 232 citations

THE USE OF AN ETHIDIUM ANALOGUE IN THE DYE-BUOYANT DENSITY PROCEDURE FOR THE ISOLATION OF CLOSED CIRCULAR DNA: THE VARIATION OF THE SUPERHELIX DENSITY OF MITOCHONDRIAL DNA

1969 • 197 citations

The Legionella pneumophila icm locus: a set of genes required for intracellular multiplication in human macrophages

1994 • 182 citations

Characterization of avirulent mutant Legionella pneumophila that survive but do not multiply within human monocytes.

1987 • 169 citations

Characterization of a new region required for macrophage killing by Legionella pneumophila

1997 • 166 citations

TPA-induced differentiation and adhesion of U937 cells: changes in ultrastructure, cytoskeletal organization and expression of cell surface antigens.

1989 • 159 citations

Intracellular multiplication of Legionnaires' disease bacteria (Legionella pneumophila) in human monocytes is reversibly inhibited by erythromycin and rifampin.

1983 • 148 citations

Fluorescein conjugates as indicators of subcellular pH

1984 • 144 citations

Statistics With Applications to the Biological and Health Sciences.

1985 • 130 citations

Molecular size-fractionation during endocytosis in macrophages.

1995 • 130 citations

Identification of Legionella pneumophila mutants that have aberrant intracellular fates

1996 • 122 citations

TheLegionella pneumophila icmGCDJBFGenes Are Required for Killing of Human Macrophages

1998 • 109 citations

Mutagenesis of Legionella pneumophila using Jn903 dllIacZ: identification of a growth‐phase‐regulated pigmentation gene

1994 • 105 citations

Molecular Genetics of Bacterial Pathogenesis

1994 • 104 citations

The HL-60 model for the interaction of human macrophages with the Legionnaires' disease bacterium.

1990 • 95 citations

Membrane sorting during phagocytosis: selective exclusion of major histocompatibility complex molecules but not complement receptor CR3 during conventional and coiling phagocytosis.

1992 • 87 citations

Identification of a cytotoxin produced by Legionella pneumophila

1980 • 76 citations

Coinoculation with Hartmannella vermiformis enhances replicative Legionella pneumophila lung infection in a murine model of Legionnaires' disease

1996 • 72 citations

Differential and sequential delivery of fluorescent lysosomal probes into phagosomes in mouse peritoneal macrophages.

1987 • 69 citations

Engulfment of the Philadelphia strain of Legionella pneumophila within pseudopod coils in human phagocytes. Comparison with other Legionella strains and species.

1989 • 61 citations

Cytotoxicity of extracellular Legionella pneumophila

1994 • 51 citations

Engulfment of the Philadelphia strain of Legionella pneumophila within pseudopod coils in human phagocytes

1989 • 49 citations

Hypoexpression of major histocompatibility complex molecules on Legionella pneumophila phagosomes and phagolysosomes

1993 • 44 citations

GENETICS OF LEGIONELLA PNEUMOPHILA VIRULENCE

1992 • 38 citations

Plaque assay for virulent Legionella pneumophila

1989 • 35 citations

[46] Measurement of vacuolar pH and cytoplasmic calcium in living cells using fluorescence microscopy

1989 • 30 citations

Legionella pneumophila Invasion of Mononuclear Phagocytes

1996 • 20 citations

Measurement of phagosome-lysosome fusion and phagosomal pH

1994 • 17 citations

Intracellular Trafficking of Legionella pneumophila within Phagocytic Cells

2014 • 4 citations