Reciprocal expression in CD4 or CD8 subsets of different members of the V alpha 11 gene family correlates with sequence polymorphism.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

An αβ T Cell Receptor Structure at 2.5 Å and Its Orientation in the TCR-MHC Complex

1996 • 1,282 citations

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

1992 • 1,116 citations

Structural Basis of Plasticity in T Cell Receptor Recognition of a Self Peptide-MHC Antigen

1998 • 685 citations

Human T-cell receptor variable gene segment families

1995 • 663 citations

T-cell-receptor affinity and thymocyte positive selection

1996 • 620 citations

Positive Selection of Thymocytes

1995 • 604 citations

CDR3 length in antigen-specific immune receptors.

1994 • 503 citations

Two Human T Cell Receptors Bind in a Similar Diagonal Mode to the HLA-A2/Tax Peptide Complex Using Different TCR Amino Acids

1998 • 438 citations

Correlations between T-cell specificity and the structure of the antigen receptor

1986 • 375 citations

The MHC Reactivity of the T Cell Repertoire Prior to Positive and Negative Selection

1997 • 322 citations

Antigenic peptide binding by class I and class II histocompatibility proteins

1994 • 302 citations

Regulation of TCR α and β gene allelic exclusion during T-cell development

1992 • 284 citations

How Many Thymocytes Audition for Selection?

1997 • 222 citations

MHC Class II–Specific T Cells Can Develop in the CD8 Lineage When CD4 Is Absent

1996 • 218 citations

A T cell clone expresses two T cell receptor α genes but uses one αβ heterodimer for allorecognition and self MHC-restricted antigen recognition

1988 • 200 citations

The Human T-Cell Receptor TCRAC/TCRDC (Cα/Cdelta;) Region: Organization, Sequence, and Evolution of 97.6 kb of DNA

1994 • 169 citations

Control of MHC Restriction by TCR V _α CDR1 and CDR2

1996 • 152 citations

The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells.

1996 • 141 citations

Variability and repertoire size of T-cell receptor Vα gene segments

1985 • 131 citations

Characterization of the T cell receptor repertoire causing collagen arthritis in mice.

1993 • 119 citations

Identification of a common docking topology with substantial variation among different TCR–peptide–MHC complexes

1998 • 116 citations

T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments.

1986 • 82 citations

Preferential positive selection of V_α2⁺CD8⁺ T cells in mouse strains expressing both H‐2^k and T cell receptor V_α^a haplotypes: determination with a V_α2‐specific monoclonal antibody

1992 • 81 citations

Genomic organization of the mouse T cell receptor V alpha family.

1990 • 72 citations

The T cell receptor V alpha 11 gene family. Analysis of allelic sequence polymorphism and demonstration of J alpha region-dependent recognition by allele-specific antibodies.

1991 • 62 citations

Preferential expression of TCR Vα regions in CD4/CD8 subsets: class discrimination or co-receptor recognition?

1998 • 52 citations

Thymic skewing of the CD4/CD8 ratio maps with the T-cell receptor α-chain locus

1998 • 52 citations

Analysis of a monoclonal rat antibody directed to the alpha-chain variable region (V alpha 3) of the mouse T cell antigen receptor.

1989 • 51 citations

T-cell receptor alpha-chain variable-region haplotypes of normal and autoimmune laboratory mouse strains.

1988 • 50 citations

Restriction fragment length polymorphisms of the mouse T-cell receptor gene families

1989 • 48 citations

Allelic exclusion of mouse T cell receptor α chains occurs at the time of thymocyte TCR up-regulation

1995 • 48 citations

Complexity, polymorphism, and recombination of mouse T-cell receptor α gene families

1989 • 44 citations

A T cell receptor V alpha region selectively expressed in CD4+ cells.

1990 • 42 citations

Influence of the NH2-terminal Amino Acid of the T Cell Receptor α Chain on Major Histocompatibility Complex (MHC) Class II + Peptide Recognition

1997 • 31 citations

Polymorphism Within a TCRAV Family Influences the Repertoire Through Class I/II Restriction

1998 • 29 citations

Preferential TCR V usage in rat repertoire selection: V_α8 imparts both positive thymic selection by and alloreactivity to RT1^f

1994 • 22 citations

MHC control of the naive TCR alpha-chain repertoire.

1994 • 22 citations

Structural analysis of the mouse T-cell receptor Tcra V2 subfamily

1994 • 19 citations

Germline genomic structure of the B10.A mouseTcra-V2 gene subfamily

1996 • 19 citations

Control of TCR V alpha-mediated positive repertoire selection and alloreactivity by differential J alpha usage and CDR3 alpha composition

1997 • 14 citations

Negative selection of Tcra-V8+CD8+ T cells by MHC class I molecules

1992 • 13 citations

Chromosome 14 in B10.A(18R) mice is recombinant and includes Tcra-V a alleles

1992 • 6 citations