The basic-helix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

The Genome of Drosophila Melanogaster

1992 • 3,126 citations

The development of Drosophila melanogaster

1994 • 3,057 citations

Genetic Transformation of Drosophila with Transposable Element Vectors

1982 • 2,995 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

Supercoil Sequencing: A Fast and Simple Method for Sequencing Plasmid DNA

1985 • 2,505 citations

Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence

1989 • 1,876 citations

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

1984 • 1,546 citations

A stable genomic source of P element transposase in Drosophila melanogaster.

1988 • 1,359 citations

Comparison of the consensus sequence flanking translational start sites inDrosophilaand vertebrates

1987 • 966 citations

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

1990 • 794 citations

Detection in situ of genomic regulatory elements in Drosophila.

1987 • 773 citations

P-element-mediated enhancer detection: a versatile method to study development in Drosophila.

1989 • 679 citations

Genetic Control of Wing Disc Development in Drosophila

1975 • 584 citations

Tissue specificity of Drosophila P element transposition is regulated at the level of mRNA splicing

1986 • 568 citations

GAL4 activates transcription in Drosophila

1988 • 521 citations

The achaete-scute gene complex of D. melanogaster: Conserved Domains in a subset of genes required for neurogenesis and their homology to myc

1987 • 501 citations

Proneural clusters of achaete-scute expression and the generation of sensory organs in the Drosophila imaginal wing disc.

1991 • 444 citations

daughterless, a Drosophila gene essential for both neurogenesis and sex determination, has sequence similarities to myc and the achaete-scute complex

1988 • 442 citations

extramacrochaetae, a negative regulator of sensory organ development in Drosophila, defines a new class of helix-loop-helix proteins

1990 • 407 citations

Regulation of achaete-scute gene expression and sensory organ pattern formation in the Drosophila wing.

1991 • 390 citations

The Drosophila extramacrochaetae locus, an antagonist of proneural genes that, like these genes, encodes a helix-loop-helix protein

1990 • 387 citations

Patterning of the Drosophila nervous system: the achaete-scute gene complex

1992 • 384 citations

Development of adult sensilla on the wing and notum of Drosophila melanogaster

1989 • 383 citations

The effect of chromosomal position on the expression of the drosophila xanthine dehydrogenase gene

1983 • 368 citations

The neurogenic gene Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats

1987 • 317 citations

Lateral inhibition and the development of the sensory bristles of the adult peripheral nervous system of Drosophila

1990 • 316 citations

Genesis of the Drosophila peripheral nervous system

1989 • 289 citations

Molecular genetics of the achaete-scute gene complex of D. melanogaster

1985 • 287 citations

Closely related transcripts encoded by the neurogenic gene complex enhancer of split of Drosophila melanogaster.

1989 • 274 citations

The achaete-scute gene complex of Drosophila melanogaster comprises four homologous genes.

1988 • 271 citations

The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete-scute protein complexes

1991 • 257 citations

Effects of Genomic Position on the Expression of Transduced Copies of the white Gene of Drosophila

1985 • 253 citations

GENETIC ANALYSIS OF THE ACHAETE-SCUTE SYSTEM OF DROSOPHILA MELANOGASTER

1979 • 247 citations

Expression of achaete and scute genes in Drosophila imaginal discs and their function in sensory organ development.

1989 • 246 citations

The Drosophila hairy protein acts in both segmentation and bristle patterning and shows homology to N-myc.

1989 • 245 citations

Transcriptional activation by heterodimers of the achaete-scute and daughterless gene products of Drosophila.

1991 • 238 citations

The emergence of sense organs in the wing disc of Drosophila

1991 • 237 citations

Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins.

1992 • 220 citations

Drosophila shaggy kinase and rat glycogen synthase kinase-3 have conserved activities and act downstream of Notch

1993 • 203 citations

The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins.

1992 • 179 citations

Molecular analysis of the asense gene, a member of the achaete-scute complex of Drosophila melanogaster, and its novel role in optic lobe development.

1989 • 178 citations

Defective neuroblast commitment in mutants of the achaete-scute complex and adjacent genes of D. melanogaster

1990 • 174 citations

Competence to develop sensory organs is temporally and spatially regulated in Drosophila epidermal primordia.

1990 • 174 citations

DEVELOPMENTAL ANALYSIS OF THE ACHAETE-SCUTE SYSTEM OF DROSOPHILA MELANOGASTER

1978 • 173 citations

Spatial regulation of proneural gene activity: auto- and cross-activation of achaete is antagonized by extramacrochaetae.

1992 • 173 citations

Molecular characterization of daughterless, a Drosophila sex determination gene with multiple roles in development.

1988 • 164 citations

X:A ratio, the primary sex-determining signal in Drosophila, is transduced by helix-loop-helix proteins

1990 • 161 citations

Lateral inhibition and cell fate during neurogenesis in Drosophila: the interactions between scute, Notch and Delta

1990 • 159 citations

Independent subpatterns of sense organs require independent genes of the achaete-scute complex in Drosophila larvae

1987 • 144 citations

Distribution and function of the lethal of scute gene product during early neurogenesis in Drosophila

1991 • 136 citations

Gene regulation in two dimensions: the proneural achaete and scute genes are controlled by combinations of axis-patterning genes through a common intergenic control region.

1992 • 130 citations

asense, a member of the Drosophila achaete-scute complex, is a proneural and neural differentiation gene.

1993 • 126 citations

Molecular analysis of the neurogenic locus Enhancer of split of Drosophila melanogaster

1987 • 119 citations

The extramacrochaetae gene provides information for sensory organ patterning.

1992 • 115 citations

The Drosophila neurogenic gene neuralized encodes a novel protein and is expressed in precursors of larval and adult neurons.

1991 • 112 citations

A region of the Drosophila genome necessary for CNS development

1979 • 111 citations

Genes in subdivision IB of the Drosophila melanogaster X-chromosome and their influence on neural development

1987 • 111 citations

Deletion analysis of the achaete-scute locus of Drosophila melanogaster.

1987 • 111 citations

Cross-Regulatory Interactions Between the Proneural achaete and scute Genes of Drosophila

1991 • 108 citations

The expression and role of a proneural gene, achaete, in the development of the larval nervous system of Drosophila.

1993 • 103 citations

The scute (T4) gene acts as a numerator element of the X:a signal that determines the state of activity of sex-lethal in Drosophila.

1989 • 93 citations

Identification of target genes of the homeotic gene Antennapedia by enhancer detection.

1991 • 92 citations

A unitary basis for different Hairy-wing mutations of Drosophila melanogaster.

1988 • 90 citations

Molecular Nature of the Drosophila Sex Determination Signal and Its Link to Neurogenesis

1991 • 86 citations

Second-site modifiers of the split mutation of Notch define genes involved in neurogenesis in Drosophila melanogaster

1990 • 80 citations

The determination of sense organs in Drosophila: interaction of scute with daughterless

1988 • 71 citations

The generation of cell diversity during early neurogenesis in Drosophila

1992 • 65 citations

The sisterless-b function of the Drosophila gene scute is restricted to the stage when the X:A ratio determines the activity of Sex-lethal

1991 • 40 citations

achaete-scute feminizing activities and Drosophila sex determination

1993 • 36 citations

Regulatory signals and signal molecules in early neurogenesis of Drosophila melanogaster

1992 • 33 citations

Function of trans-acting genes of theachaete-scute complex in sensory organ patterning in the mesonotum ofDrosophila

1991 • 29 citations

Molecular characterization of the lethal of scute genetic function

1993 • 24 citations

Two different sets of cis elements regulate scute to establish two different sensory patterns

1989 • 23 citations

Deleted Work

1955 • 0 citations