Regulation of cell differentiation by the Drosophila Jun kinase cascade

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

DEVELOPMENT IN DROSOPHILA MELANOGASTER

1927 • 2,909 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

Mutations affecting the pattern of the larval cuticle inDrosophila melanogaster

1984 • 1,546 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

Parallel signal processing among mammalian MAPKs

1995 • 1,015 citations

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

1994 • 1,005 citations

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion.

1994 • 985 citations

Small GTP-Binding Proteins and the Regulation of the Actin Cytoskeleton

1994 • 822 citations

The activities of two Ets-related transcription factors required for drosophila eye development are modulated by the Ras/MAPK pathway

1994 • 690 citations

The role of RhoA in tissue polarity and Frizzled signalling

1997 • 558 citations

Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function.

1993 • 424 citations

A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila.

1996 • 407 citations

hemipterous encodes a novel drosophila MAP kinase kinase, required for epithelial cell sheet movement

1995 • 331 citations

The ETS domain protein pointed-P2 is a target of MAP kinase in the sevenless signal transduction pathway

1994 • 315 citations

The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye.

1996 • 310 citations

Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinase.

1988 • 279 citations

Negative control of photoreceptor development in Drosophila by the product of the yan gene, an ETS domain protein

1992 • 258 citations

Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila.

1996 • 215 citations

A Drosophila Homolog of the Rac- and Cdc42-Activated Serine/Threonine Kinase PAK Is a Potential Focal Adhesion and Focal Complex Protein That Colocalizes with Dynamic Actin Structures

1996 • 204 citations

Coupling of Jun amino-terminal kinase and Decapentaplegic signaling pathways in Drosophila morphogenesis.

1997 • 200 citations

MEK Kinase Is Involved in Tumor Necrosis Factor α-Induced NF-κB Activation and Degradation of IκB-α

1996 • 197 citations

Drosophila Jun kinase regulates expression of decapentaplegic via the ETS-domain protein Aop and the AP-1 transcription factor DJun during dorsal closure.

1997 • 194 citations

CDC42 and Rac1 control different actin-dependent processes in the Drosophila wing disc epithelium.

1995 • 190 citations

The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain.

1994 • 171 citations

A dominant inhibitory version of the small GTP-binding protein Rac disrupts cytoskeletal structures and inhibits developmental cell shape changes in Drosophila

1995 • 169 citations

Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement.

1997 • 166 citations

Jun in Drosophila development: redundant and nonredundant functions and regulation by two MAPK signal transduction pathways.

1997 • 142 citations

Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis.

1994 • 137 citations

puckered, a gene involved in position-specific cell differentiation in the dorsal epidermis of the Drosophila larva

1993 • 119 citations

JUN cooperates with the ETS domain protein pointed to induce photoreceptor R7 fate in the Drosophila eye

1995 • 118 citations

Signalling pathways initiated by receptor protein tyrosine kinases in Drosophila

1994 • 102 citations

Drosophila Jun mediates Ras-dependent photoreceptor determination

1994 • 94 citations

The tumor suppressor gene, lethal(2)giant larvae (l(2)gl), is required for cell shape change of epithelial cells during Drosophila development

1996 • 91 citations

Isolation of Mutations in the Drosophila Homologues of the Human Neurofibromatosis 2 and Yeast CDC42 Genes Using a Simple and Efficient Reverse-Genetic Method

1997 • 85 citations

Phosphorylation of Drosophila Jun by the MAP kinase rolled regulates photoreceptor differentiation.

1996 • 57 citations

The l(2)gl homologue of Drosophila pseudoobscura suppresses tumorigenicity in transgenic Drosophila melanogaster.

1993 • 21 citations