Interactions between Newly Synthesized Glycoproteins, Calnexin and a Network of Resident Chaperones in the Endoplasmic Reticulum

Protein folding in the cell

1992 • 4,138 citations

Brefeldin A: insights into the control of membrane traffic and organelle structure.

1992 • 1,848 citations

STRUCTURAL BASIS OF LECTIN-CARBOHYDRATE RECOGNITION

1996 • 1,074 citations

Protein Oligomerization in the Endoplasmic Reticulum

1989 • 993 citations

Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control.

1994 • 815 citations

Quality control in the secretory pathway

1995 • 679 citations

Association of folding intermediates of glycoproteins with calnexin during protein maturation

1993 • 558 citations

Glucose trimming and reglucosylation determine glycoprotein association with calnexin in the endoplasmic reticulum

1995 • 544 citations

SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane.

1991 • 544 citations

Identification, by a monoclonal antibody, of a 53-kD protein associated with a tubulo-vesicular compartment at the cis-side of the Golgi apparatus.

1988 • 488 citations

The Molecular Chaperone Calnexin Binds Glc1Man9GlcNAc2 Oligosaccharide as an Initial Step in Recognizing Unfolded Glycoproteins

1995 • 417 citations

Assembly of influenza hemagglutinin trimers and its role in intracellular transport.

1986 • 413 citations

Glycosidase inhibitors: inhibitors of N‐linked oligosaccharide processing

1991 • 373 citations

Perturbation of cellular calcium induces secretion of luminal ER proteins

1989 • 370 citations

Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator.

1994 • 359 citations

Regulation of MHC Class I Transport by the Molecular Chaperone, Calnexin (p88, IP90)

1994 • 351 citations

Membrane fusion activity of the influenza virus hemagglutinin. The low pH-induced conformational change.

1985 • 341 citations

Folding of influenza hemagglutinin in the endoplasmic reticulum.

1991 • 318 citations

Folding of VSV G Protein: Sequential Interaction with BiP and Calnexin

1994 • 316 citations

Interactions of misfolded influenza virus hemagglutinin with binding protein (BiP).

1989 • 312 citations

The involvement of calcium in transport of secretory proteins from the endoplasmic reticulum

1990 • 310 citations

The endoplasmic reticulum as a protein-folding compartment

1992 • 296 citations

Calnexin and calreticulin promote folding, delay oligomerization and suppress degradation of influenza hemagglutinin in microsomes.

1996 • 288 citations

Proteins of rough microsomal membranes related to ribosome binding. I. Identification of ribophorins I and II, membrane proteins characteristics of rough microsomes

1978 • 281 citations

Definition of the Lectin-like Properties of the Molecular Chaperone, Calreticulin, and Demonstration of Its Copurification with Endomannosidase from Rat Liver Golgi

1996 • 280 citations

A set of endoplasmic reticulum proteins possessing properties of molecular chaperones includes Ca(2+)-binding proteins and members of the thioredoxin superfamily.

1994 • 279 citations

Transient, lectin-like association of calreticulin with folding intermediates of cellular and viral glycoproteins.

1995 • 274 citations

Calreticulin Functions as a Molecular Chaperone in the Biosynthesis of Myeloperoxidase

1995 • 260 citations

Cotranslational folding and calnexin binding during glycoprotein synthesis.

1995 • 248 citations

Involvement of the stress protein HSP47 in procollagen processing in the endoplasmic reticulum

1992 • 241 citations

Deficient uridine diphosphate-N-acetylglucosamine:glycoprotein N-acetylglucosaminyltransferase activity in a clone of Chinese hamster ovary cells with altered surface glycoproteins.

1975 • 227 citations

Interaction with newly synthesized and retained proteins in the endoplasmic reticulum suggests a chaperone function for human integral membrane protein IP90 (calnexin)

1993 • 203 citations

The molecular chaperone calnexin facilitates folding and assembly of class I histocompatibility molecules.

1996 • 201 citations

Recycling of proteins between the endoplasmic reticulum and Golgi complex

1991 • 194 citations

Retention and retrieval: both mechanisms cooperate to maintain calreticulin in the endoplasmic reticulum

1994 • 154 citations

Chaperone Function of Calreticulin When Expressed in the Endoplasmic Reticulum as the Membrane-anchored and Soluble Forms

1995 • 153 citations

Formation of intermolecular disulfide bonds on nascent immunoglobulin polypeptides.

1979 • 147 citations

A role for calnexin (IP90) in the assembly of class II MHC molecules.

1994 • 144 citations

ATP-coupled transport of vesicular stomatitis virus G protein between the endoplasmic reticulum and the Golgi.

1986 • 141 citations

Quaternary structure of influenza virus hemagglutinin after acid treatment

1986 • 138 citations

Calreticulin Interacts with Newly Synthesized Human Immunodeficiency Virus Type 1 Envelope Glycoprotein, Suggesting a Chaperone Function Similar to That of Calnexin

1996 • 134 citations

Prolonged association of temperature-sensitive mutants of human P-glycoprotein with calnexin during biogenesis.

1994 • 124 citations

Persistence of glucose residues on core oligosaccharides prevents association of TCR alpha and TCR beta proteins with calnexin and results specifically in accelerated degradation of nascent TCR alpha proteins within the endoplasmic reticulum.

1994 • 117 citations

Interaction of Calreticulin with Protein Disulfide Isomerase

1995 • 115 citations

Association between calnexin and a secretion-incompetent variant of human alpha 1-antitrypsin.

1994 • 112 citations

Folding and oligomerization of influenza hemagglutinin in the ER and the intermediate compartment.

1995 • 95 citations

Reticuloplasmins: a novel group of proteins in the endoplasmic reticulum

1987 • 90 citations

Calnexin Fails to Associate with Substrate Proteins in Glucosidase-deficient Cell Lines

1995 • 86 citations

Calnexin Influences Folding of Human Class I Histocompatibility Proteins but Not Their Assembly with β2-Microglobulin

1995 • 79 citations

Post-translational folding of influenza hemagglutinin in isolated endoplasmic reticulum-derived microsomes.

1993 • 71 citations

A chaperone with a sweet tooth

1993 • 58 citations

Architectural editing: determining the fate of newly synthesized membrane proteins.

1989 • 58 citations

A novel glycosylation phenotype expressed by Lec23, a Chinese hamster ovary mutant deficient in alpha-glucosidase I.

1991 • 53 citations

Struktur und Funktion des endoplasmatischen Retikulums

1975 • 24 citations

Divalent cation-dependent stimulation of ligand binding to the 46-kDa mannose 6-phosphate receptor correlates with divalent cation-dependent tetramerization.

1992 • 15 citations

Integration and control of metabolic processes: pure and applied aspects

1988 • 11 citations

Protein Folding in the Endoplasmic Reticulum

1993 • 10 citations

Lee Hood: still climbing mountains

1997 • 5 citations