Definition of the Lectin-like Properties of the Molecular Chaperone, Calreticulin, and Demonstration of Its Copurification with Endomannosidase from Rat Liver Golgi

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

A simplification of the protein assay method of Lowry et al. which is more generally applicable

1977 • 8,485 citations

How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum.

1994 • 617 citations

Association of folding intermediates of glycoproteins with calnexin during protein maturation

1993 • 558 citations

Glucose trimming and reglucosylation determine glycoprotein association with calnexin in the endoplasmic reticulum

1995 • 544 citations

Calnexin: a membrane-bound chaperone of the endoplasmic reticulum

1994 • 533 citations

Multisubunit assembly of an integral plasma membrane channel protein, gap junction connexin43, occurs after exit from the ER

1993 • 492 citations

The Molecular Chaperone Calnexin Binds Glc1Man9GlcNAc2 Oligosaccharide as an Initial Step in Recognizing Unfolded Glycoproteins

1995 • 417 citations

Calreticulin

1992 • 402 citations

Reproducible high yield sequencing of proteins electrophoretically separated and transferred to an inert support.

1988 • 375 citations

Biochemical analysis of membranes

1977 • 351 citations

The role of n-glycans in the secretory pathway

1995 • 295 citations

Hepatitis B surface antigen assembles in a post-ER, pre-Golgi compartment.

1992 • 277 citations

Transient, lectin-like association of calreticulin with folding intermediates of cellular and viral glycoproteins.

1995 • 274 citations

Calreticulin Functions as a Molecular Chaperone in the Biosynthesis of Myeloperoxidase

1995 • 260 citations

Glucose removal from N-linked oligosaccharides is required for efficient maturation of certain secretory glycoproteins from the rough endoplasmic reticulum to the Golgi complex.

1984 • 242 citations

Isolation of a Golgi-rich fraction from rat liver

1970 • 222 citations

Four Intracisternal Calcium-binding Glycoproteins from Rat Liver Microsomes with High Affinity for Calcium

1989 • 200 citations

Golgi endo-alpha-D-mannosidase from rat liver, a novel N-linked carbohydrate unit processing enzyme.

1987 • 183 citations

Purification and characterization of alpha-D-mannosidase from rat liver golgi membranes.

1977 • 178 citations

Lipid-saccharide intermediates in glycoprotein biosynthesis. I. Formation of an oligosaccharide-lipid by thyroid slices and evaluation of its role in protein glycosylation.

1976 • 178 citations

Comparative rates of transfer of lipid-linked oligosaccharides to endogenous glycoprotein acceptors in vitro.

1977 • 173 citations

Cell Surface Calreticulin Is a Putative Mannoside Lectin Which Triggers Mouse Melanoma Cell Spreading

1995 • 160 citations

Complete amino acid sequence of the FK506 and rapamycin binding protein, FKBP, isolated from calf thymus

1991 • 159 citations

Substrate specificities of rat liver microsomal glucosidases which process glycoproteins.

1980 • 153 citations

Chaperone Function of Calreticulin When Expressed in the Endoplasmic Reticulum as the Membrane-anchored and Soluble Forms

1995 • 153 citations

Evaluation of the role of rat liver Golgi endo-alpha-D-mannosidase in processing N-linked oligosaccharides.

1988 • 151 citations

Demonstration that Golgi endo-alpha-D-mannosidase provides a glucosidase-independent pathway for the formation of complex N-linked oligosaccharides of glycoproteins.

1990 • 148 citations

The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes.

1993 • 137 citations

Macromolecular organization of basement membranes. Characterization and comparison of glomerular basement membrane and lens capsule components by immunochemical and lectin affinity procedures.

1986 • 130 citations

Calnexin Recognizes Carbohydrate and Protein Determinants of Class I Major Histocompatibility Complex Molecules

1995 • 129 citations

Persistence of glucose residues on core oligosaccharides prevents association of TCR alpha and TCR beta proteins with calnexin and results specifically in accelerated degradation of nascent TCR alpha proteins within the endoplasmic reticulum.

1994 • 117 citations

The molecular chaperone calnexin is expressed on the surface of immature thymocytes in association with clonotype-independent CD3 complexes.

1995 • 115 citations

Processing of the carbohydrate units of thyroglobulin.

1981 • 112 citations

Glycosylation of proteins by oligosaccharide-lipids. Studies on a thyroid enzyme involved in oligosaccharide transfer and the role of glucose in this reaction.

1979 • 105 citations

Castanospermine inhibits glucosidase I and glycoprotein secretion in human hepatoma cells

1985 • 104 citations

Release of glucose-containing polymannose oligosaccharides during glycoprotein biosynthesis. Studies with thyroid microsomal enzymes and slices.

1983 • 98 citations

Demonstration that a kifunensine-resistant alpha-mannosidase with a unique processing action on N-linked oligosaccharides occurs in rat liver endoplasmic reticulum and various cultured cells.

1993 • 95 citations

An Endoplasmic Reticulum Protein, Calreticulin, Is Transported into the Acrosome of Rat Sperm

1993 • 90 citations

Different sorting of Lys-Asp-Glu-Leu proteins in rat liver.

1992 • 89 citations

Inhibition of glucose trimming by castanospermine results in rapid degradation of unassembled major histocompatibility complex class I molecules.

1993 • 86 citations

Intracellular compartmentalization and degradation of free polymannose oligosaccharides released during glycoprotein biosynthesis.

1994 • 84 citations

Endoplasmic Reticulum Kifunensine-Resistant α-Mannosidase Is Enzymatically and Immunologically Related to the Cytosolic α-Mannosidase

1996 • 75 citations

Calreticulin: from Ca2+ binding to control of gene expression

1994 • 57 citations

Nonselective utilization of the endomannosidase pathway for processing glycoproteins by human hepatoma (HepG2) cells.

1992 • 54 citations

Effect of anion-specific inhibitors on the utilization of sugar nucleotides for N-linked carbohydrate unit assembly by thyroid endoplasmic reticulum vesicles.

1985 • 53 citations

Studies on the regulation of the biosynthesis of glucose-containing oligosaccharide-lipids. Effect of energy deprivation.

1983 • 51 citations

Glucosidase II, a protein of the endoplasmic reticulum with high mannose oligosaccharide chains and a rapid turnover.

1987 • 47 citations

Blockage of tropoelastin secretion by monensin represses tropoelastin synthesis at a pretranslational level in rat smooth muscle cells.

1985 • 39 citations

Ligand affinity chromatographic purification of rat liver Golgi endomannosidase.

1994 • 22 citations