SP100B, a repressor of gene expression preferentially binds to DNA with unmethylated CpGs

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to Methylated DNA

1992 • 1,331 citations

Identification and Characterization of a Family of Mammalian Methyl-CpG Binding Proteins

1998 • 1,317 citations

Number of CpG islands and genes in human and mouse.

1993 • 986 citations

Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs

1989 • 655 citations

HMG1 and 2, and related ‘architectural’ DNA-binding proteins

2001 • 609 citations

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation.

1989 • 554 citations

The HP1 protein family: getting a grip on chromatin

2000 • 476 citations

Structure, function and evolution of CpG island promoters

2003 • 425 citations

Autoantibodies to the Nuclear Sp100 Protein in Primary Biliary Cirrhosis and Associated Diseases: Epitope Specificity and Immunoglobulin Class Distribution

1992 • 365 citations

Sp1 transcription factor binds DNA and activates transcription even when the binding site is CpG methylated.

1988 • 308 citations

Methylation of CpG sequences in eukaryotic DNA

1981 • 289 citations

Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis.

1990 • 266 citations

The Nuclear Dot Protein Sp100, Characterization of Domains Necessary for Dimerization, Subcellular Localization, and Modification by Small Ubiquitin-like Modifiers

1999 • 258 citations

DNA viruses and viral proteins that interact with PML nuclear bodies

2001 • 245 citations

Binding of a simian virus 40 T antigen-related protein to DNA

1981 • 233 citations

CpG methylation as a mechanism for the regulation of E2F activity

2000 • 222 citations

The SAND domain structure defines a novel DNA-binding fold in transcriptional regulation.

2001 • 222 citations

Cytosine methylation does not affect binding of transcription factor Sp1.

1988 • 201 citations

Methylation-Mediated Transcriptional Silencing in Euchromatin by Methyl-CpG Binding Protein MBD1 Isoforms

1999 • 198 citations

Chromatin components as part of a putative transcriptional repressing complex

1998 • 179 citations

The Autoimmune Regulator (AIRE) Is a DNA-binding Protein

2001 • 172 citations

Sp110 Localizes to the PML-Sp100 Nuclear Body and May Function as a Nuclear Hormone Receptor Transcriptional Coactivator

2000 • 152 citations

DNA methylation and chromatin structure: The puzzling CpG islands

2004 • 141 citations

DEAF-1, a novel protein that binds an essential region in a Deformed response element.

1996 • 138 citations

Autoimmune sera recognize a 100 kD nuclear protein antigen (sp-100).

1987 • 105 citations

Identification and Characterization of a Leukocyte-specific Component of the Nuclear Body

1996 • 102 citations

Herpes Simplex Virus Type 1 DNA Is Immunostimulatory In Vitro and In Vivo

2003 • 83 citations

Cytosine methylation in CTF and Spl recognition sites of an HSV tk promoter: effects on transcriptionin vivoand on factor bindingin vitro

1989 • 79 citations

Characterization of a Nuclear Deformed Epidermal Autoregulatory Factor-1 (DEAF-1)-Related (NUDR) Transcriptional Regulator Protein

1998 • 73 citations

Splice variants of the nuclear dot-associated Sp100 protein contain homologies to HMG-1 and a human nuclear phosphoprotein-box motif

1999 • 61 citations

Nuclear DEAF-1-related (NUDR) Protein Contains a Novel DNA Binding Domain and Represses Transcription of the Heterogeneous Nuclear Ribonucleoprotein A2/B1 Promoter

1999 • 53 citations

Mapping DNA-binding domains of the autoimmune regulator protein

2004 • 46 citations

Properties of the Glucocorticoid Modulatory Element Binding Proteins GMEB-1 and -2: Potential New Modifiers of Glucocorticoid Receptor Transactivation and Members of the Family of KDWK Proteins

2000 • 46 citations

Crystal Structure and Nuclear Magnetic Resonance Analyses of the SAND Domain from Glucocorticoid Modulatory Element Binding Protein-1 Reveals Deoxyribonucleic Acid and Zinc Binding Regions

2003 • 44 citations

Two New Members of the Emerging KDWK Family of Combinatorial Transcription Modulators Bind as a Heterodimer to Flexibly Spaced PuCGPy Half-Sites

1999 • 33 citations

SP100B is a repressor of gene expression

2005 • 25 citations

A consensus DNA recognition motif for two KDWK transcription factors identifies flexible-length, CpG-methylation sensitive cognate binding sites in the majority of human promoters

2001 • 25 citations

Cloning of a mouse glucocorticoid modulatory element binding protein, a new member of the KDWK family

2000 • 18 citations

Identification of a Motif in the C Terminus of Herpes Simplex Virus Regulatory Protein ICP4 That Contributes to Activation of Transcription

2002 • 17 citations

Properties of the Glucocorticoid Modulatory Element Binding Proteins GMEB-1 and -2: Potential New Modifiers of Glucocorticoid Receptor Transactivation and Members of the Family of KDWK Proteins

2000 • 13 citations