Sp110 Localizes to the PML-Sp100 Nuclear Body and May Function as a Nuclear Hormone Receptor Transcriptional Coactivator

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Primary Biliary Cirrhosis

1987 • 1,981 citations

Structure and ligand of a histone acetyltransferase bromodomain

1999 • 1,625 citations

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

1978 • 1,624 citations

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1991 • 1,463 citations

Positional cloning of the APECED gene

1997 • 1,385 citations

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus

1990 • 1,349 citations

A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2

1997 • 1,221 citations

A novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAP1 between the cytosol and the nuclear pore complex.

1996 • 1,161 citations

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

1997 • 1,155 citations

Deconstructing a Disease: RAR, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia

1999 • 1,042 citations

NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)

1991 • 884 citations

The PHD finger: Implications for chromatin-mediated transcriptional regulation

1995 • 857 citations

A novel rapid assay for chloramphenicol acetyltransferase gene expression

1987 • 802 citations

Manipulation of Adenovirus Vectors

2003 • 780 citations

Molecular Analysis of Acute Promyelocytic Leukemia Breakpoint Cluster Region on Chromosome 17

1990 • 650 citations

The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18.

1995 • 627 citations

Determination of Nucleotide Sequences in DNA

1981 • 593 citations

Pml is essential for multiple apoptotic pathways

1998 • 564 citations

How proteins enter the nucleus

1991 • 555 citations

A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors.

1996 • 532 citations

Role of PML in Cell Growth and the Retinoic Acid Pathway

1998 • 522 citations

Reporter genes: Application to the study of mammalian gene transcription

1990 • 466 citations

Primary Biliary Cirrhosis

1996 • 442 citations

Interaction between an Integral Protein of the Nuclear Envelope Inner Membrane and Human Chromodomain Proteins Homologous to HP1

1996 • 398 citations

PML induces a novel caspase-independent death process

1998 • 384 citations

The bromodomain: a conserved sequence found in human,Drosophilaand yeast proteins

1992 • 375 citations

Evidence for Covalent Modification of the Nuclear Dot–associated Proteins PML and Sp100 by PIC1/SUMO-1

1997 • 329 citations

Identification of a novel nuclear domain.

1991 • 285 citations

Interaction of SP100 with HP1 proteins: A link between the promyelocytic leukemia-associated nuclear bodies and the chromatin compartment

1998 • 269 citations

Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis.

1990 • 266 citations

Localization of nascent RNA and CREB binding protein with the PML-containing nuclear body

1998 • 244 citations

Rearrangements and aberrant expression of the retinoic acid receptor alpha gene in acute promyelocytic leukemias.

1990 • 212 citations

Human Cytomegalovirus Immediate Early Interaction with Host Nuclear Structures: Definition of an Immediate Transcript Environment

1997 • 205 citations

Chromatin components as part of a putative transcriptional repressing complex

1998 • 179 citations

Structure, Organization, and Dynamics of Promyelocytic Leukemia Protein Nuclear Bodies

1998 • 174 citations

Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling

1999 • 173 citations

TIF1γ, a novel member of the transcriptional intermediary factor 1 family

1999 • 161 citations

Nuclear dots: Actors on Many Stages

1997 • 148 citations

DEAF-1, a novel protein that binds an essential region in a Deformed response element.

1996 • 138 citations

Identification and Characterization of a Leukocyte-specific Component of the Nuclear Body

1996 • 102 citations

LYSP100-associated nuclear domains (LANDs): description of a new class of subnuclear structures and their relationship to PML nuclear bodies

1996 • 72 citations

Structural and Functional Heterogeneity of Nuclear Bodies

1999 • 62 citations

Molecular cloning of two new interferon-induced, highly related nuclear phosphoproteins.

1993 • 52 citations