Differences Between IL-4- and IL-4 Receptor α-Deficient Mice in Chronic Leishmaniasis Reveal a Protective Role for IL-13 Receptor Signaling

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

1989 • 1,462 citations

Identification of a T cell-derived b cell growth factor distinct from interleukin 2.

1982 • 1,095 citations

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

1994 • 888 citations

lnterleukin-13 is a new human lymphokine regulating inflammatory and immune responses

1993 • 877 citations

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.

1990 • 629 citations

Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-4 Receptor

1993 • 593 citations

IL-13, IL-4Rα, and Stat6 Are Required for the Expulsion of the Gastrointestinal Nematode Parasite Nippostrongylus brasiliensis

1998 • 582 citations

A new cytokine receptor superfamily

1990 • 506 citations

Genetically resistant mice lacking interleukin‐12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response

1996 • 483 citations

IL-10 synergizes with IL-4 and transforming growth factor-beta to inhibit macrophage cytotoxic activity.

1992 • 422 citations

IL-4 induces a Th2 response in Leishmania major-infected mice.

1992 • 403 citations

Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood mononuclear cells: priming for IL-12 and tumor necrosis factor alpha production.

1995 • 372 citations

Susceptibility to Leishmania major Infection in Interleukin-4-Deficient Mice

1996 • 292 citations

A Critical Role for IL-13 in Resistance to Intestinal Nematode Infection

1998 • 284 citations

Immune responses associated with susceptibility of C57BL/10 mice to Leishmania amazonensis

1993 • 277 citations

IL-4-deficient Balb/c mice resist infection with Leishmania major.

1996 • 273 citations

Modulation of murine macrophage function by IL-13.

1993 • 251 citations

Metacyclogenesis is a major determinant of Leishmania promastigote virulence and attenuation

1987 • 233 citations

Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice.

1985 • 225 citations

Differences between IL-4Rα-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses

1998 • 204 citations

Structural comparison and chromosomal localization of the human and mouse IL-13 genes.

1993 • 167 citations

IgD can largely substitute for loss of IgM function in B cells

1998 • 141 citations

Efficient targeting of the IL-4 gene in a BALB/c embryonic stem cell line

1996 • 137 citations

Effect of Transmembrane and Cytoplasmic Domains of IgE on the IgE Response

1997 • 133 citations

Induction of Th1 and Th2 CD4+ subsets during murine Leishmania major infection

1991 • 102 citations

Interleukin 13: novel role in direct regulation of proliferation and differentiation of primitive hematopoietic progenitor cells.

1994 • 56 citations

Two distinct stimulus-dependent pathways lead to production of soluble murine interleukin-4 receptor.

1996 • 45 citations

The Murine Interleukin-4 Receptor Gene: Genomic Structure, Expression and Potential for Alternative Splicing

1992 • 43 citations

Interleukin-7 enhances antimicrobial activity against Leishmania major in murine macrophages

1993 • 41 citations

Mouse macrophage development in the absence of the common γ chain: defining receptor complexes responsible for IL‐4 and IL‐13 signaling

1997 • 38 citations

Effects of IL-13 on murine listeriosis

1997 • 30 citations

Interleukin 4 and interleukin 13: same response, different receptors

1997 • 14 citations