Chlamydia Inhibits Interferon γ–inducible Major Histocompatibility Complex Class II Expression by Degradation of Upstream Stimulatory Factor 1

Structure of 20S proteasome from yeast at 2.4Å resolution

1997 • 2,211 citations

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

Immunity to Intracellular Bacteria

1993 • 1,085 citations

The Human Cytomegalovirus US11 Gene Product Dislocates MHC Class I Heavy Chains from the Endoplasmic Reticulum to the Cytosol

1996 • 1,083 citations

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes

1998 • 1,012 citations

Viral Strategies of Immune Evasion

1998 • 791 citations

Interaction of chlamydiae and host cells in vitro

1991 • 734 citations

Inhibition of Apoptosis in Chlamydia-infected Cells: Blockade of Mitochondrial Cytochrome c Release and Caspase Activation

1998 • 586 citations

Persistent chlamydiae: from cell culture to a paradigm for chlamydial pathogenesis

1994 • 549 citations

Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA

1997 • 510 citations

REGULATION OF MHC CLASS II GENES: Lessons from a Disease

1996 • 488 citations

The ER-Luminal Domain of the HCMV Glycoprotein US6 Inhibits Peptide Translocation by TAP

1997 • 472 citations

Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains.

1996 • 412 citations

Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways.

1997 • 365 citations

New Knowledge of Chlamydiae and the Diseases They Cause

1975 • 364 citations

Activation of the MHC Class II Transactivator CIITA by Interferon-γ Requires Cooperative Interaction between Stat1 and USF-1

1998 • 358 citations

Human Cytomegalovirus Inhibits Major Histocompatibility Complex Class II Expression By Disruption of the Jak/Stat Pathway

1998 • 337 citations

Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.

1994 • 318 citations

Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome

1997 • 295 citations

The human cytomegalovirus US6 glycoprotein inhibits transporter associated with antigen processing-dependent peptide translocation

1997 • 274 citations

A proteolytic system that compensates for loss of proteasome function

1998 • 271 citations

Self-compartmentalizing proteases

1997 • 216 citations

Vaccination against Chlamydial Genital Tract Infection after Immunization with Dendritic Cells Pulsed Ex Vivo with Nonviable Chlamydiae

1998 • 194 citations

Chlamydia trachomatis has penicillin-binding proteins but not detectable muramic acid

1982 • 180 citations

Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes

1998 • 179 citations

Chlamydia pneumoniae and Cardiovascular Disease

1998 • 177 citations

Regulatory Subunits of Energy-Dependent Proteases

1997 • 169 citations

Human cytomegalovirus US2 destabilizes major histocompatibility complex class I heavy chains

1997 • 161 citations

Upstream Stimulatory Factor Binding to the E-box at −65 Is Required for Insulin Regulation of the Fatty Acid Synthase Promoter

1997 • 151 citations

T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC); responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring

1996 • 149 citations

Trophoblast Class I Major Histocompatibility Complex (MHC) Products Are Resistant to Rapid Degradation Imposed by the Human Cytomegalovirus (HCMV) Gene Products US2 and US11

1998 • 142 citations

The HCMV Gene Products US11 and US2 Differ in Their Ability to Attack Allelic Forms of Murine Major Histocompatibility Complex (MHC) Class I Heavy Chains

1997 • 138 citations

The helix-loop-helix containing transcription factor USF binds to and transactivates the promoter of the p53 tumor suppressor gene

1993 • 119 citations

Kinetics of gamma interferon binding and induction of major histocompatibility complex class II mRNA in Leishmania-infected macrophages.

1988 • 103 citations

Human Cytomegalovirus Inhibits Peptide Translocation into the Endoplasmic Reticulum for MHC Class I Assembly

1996 • 101 citations

Targeted Inhibition of Interferon-γ-dependent Intercellular Adhesion Molecule-1 (ICAM-1) Expression Using Dominant-Negative Stat1

1997 • 100 citations

Interferon-γ-Stimulated Human Keratinocytes Express the Genes Necessary for the Production of Peptide-Loaded MHC Class II Molecules

1998 • 99 citations

Murine Cytomegalovirus Inhibits Interferon γ–induced Antigen Presentation to CD4 T Cells by Macrophages Via Regulation of Expression of Major Histocompatibility Complex Class II–associated Genes

1998 • 86 citations

Involvement of Two Regulatory Elements in Interferon-γ-Regulated Expression of Human Indoleamine 2,3-Dioxygenase Gene

1995 • 73 citations

Th1 cells specific for a secreted protein of Listeria monocytogenes are protective in vivo.

1998 • 60 citations

Murine Cytomegalovirus Infection Inhibits IFNγ-Induced MHC Class II Expression on Macrophages: The Role of Type I Interferon

1998 • 56 citations

Th1 Cells Specific for a Secreted Protein ofListeria monocytogenesAre Protective In Vivo

1998 • 51 citations

Intracellular Formation and Cell Surface Expression of a Complex of an Intact Lysosomal Protein and MHC Class II Molecules

1998 • 36 citations

Beta Interferon Is Produced by Chlamydia trachomatis -Infected Fibroblast-Like Synoviocytes and Inhibits Gamma Interferon-Induced HLA-DR Expression

1998 • 34 citations

Evidence for a significant role of CD4+ T cells in adoptive immunity to Listeria monocytogenes in the liver.

1994 • 25 citations

Chlamydia pneumoniae and cardiovascular disease.

1997 • 25 citations

The Basic Region/Helix‐Loop‐Helix/Leucine Repeat Transcription Factor USF Interferes with Ras Transformation

1996 • 22 citations

The role of interferon ? in human cytomegalovirus-mediated inhibition of HLA DR induction on endothelial cells

1995 • 22 citations

Suppression of major histocompatibility complex class I and class II gene expression inListeria monocytogenes-infected murine macrophages

1998 • 16 citations

Destruction of proteins as a creative force

1997 • 13 citations

Suppression of major histocompatibility complex class I and class II gene expression in Listeria monocytogenes-infected murine macrophages

1998 • 11 citations

Inhibition of MHC class I and class II cell surface expression on bovine endothelial cells upon infection with Cowdria ruminantium

1998 • 9 citations