Human cytomegalovirus US2 destabilizes major histocompatibility complex class I heavy chains

Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

1978 • 1,954 citations

Reconstitution of Cellular Immunity against Cytomegalovirus in Recipients of Allogeneic Bone Marrow by Transfer of T-Cell Clones from the Donor

1995 • 1,828 citations

Analysis of the Protein-Coding Content of the Sequence of Human Cytomegalovirus Strain AD169

1990 • 1,280 citations

Restoration of Viral Immunity in Immunodeficient Humans by the Adoptive Transfer of T Cell Clones

1992 • 1,227 citations

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

Sec6l-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

1996 • 1,101 citations

The Human Cytomegalovirus US11 Gene Product Dislocates MHC Class I Heavy Chains from the Endoplasmic Reticulum to the Cytosol

1996 • 1,083 citations

Inhibition of antigen processing by the internal repeat region of the Epstein–Barr virus nuclear antigen-1

1995 • 820 citations

Herpes simplex virus turns off the TAP to evade host immunity

1995 • 736 citations

STRUCTURE, FUNCTION, AND DIVERSITY OF CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULES

1990 • 693 citations

A viral inhibitor of peptide transporters for antigen presentation

1995 • 599 citations

A cytosolic herpes simplex virus protein inhibits antigen presentation to CD8+ T lymphocytes

1994 • 553 citations

Recovery of HLA-restricted cytomegalovirus (CMV)-specific T-cell responses after allogeneic bone marrow transplant: correlation with CMV disease and effect of ganciclovir prophylaxis

1994 • 511 citations

CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity

1987 • 432 citations

GENERATION, TRANSLOCATION, AND PRESENTATION OF MHC CLASS I-RESTRICTED PEPTIDES

1995 • 428 citations

Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains.

1996 • 412 citations

Human cytomegalovirus inhibits antigen presentation by a sequential multistep process.

1996 • 379 citations

Identification of the major late human cytomegalovirus matrix protein pp65 as a target antigen for CD8⁺ virus‐specific cytotoxic T lymphocytes

1994 • 359 citations

Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47.

1996 • 350 citations

Lack of HLA class I antigen expression by cultured melanoma cells FO-1 due to a defect in B2m gene expression.

1991 • 304 citations

Cytomegalovirus selectively blocks antigen processing and presentation of its immediate–early gene product

1996 • 287 citations

Evolutionary conservation of components of the protein translocation complex

1994 • 283 citations

Multiple independent loci within the human cytomegalovirus unique short region down-regulate expression of major histocompatibility complex class I heavy chains

1995 • 278 citations

Assembly and maturation of HLA-A and HLA-B antigens in vivo

1979 • 278 citations

Human cytomegalovirus-specific cytotoxic T cells. Relative frequency of stage-specific CTL recognizing the 72-kD immediate early protein and glycoprotein B expressed by recombinant vaccinia viruses.

1988 • 255 citations

Class I MHC-restricted cytotoxic T lymphocyte recognition of cells infected with human cytomegalovirus does not require endogenous viral gene expression.

1991 • 235 citations

Human cytomegalovirus down-regulates HLA class I expression by reducing the stability of class I H chains.

1993 • 215 citations

Cytomegalovirus prevents antigen presentation by blocking the transport of peptide-loaded major histocompatibility complex class I molecules into the medial-Golgi compartment.

1992 • 204 citations

A nonstructural viral protein expressed by a recombinant vaccinia virus protects against lethal cytomegalovirus infection

1988 • 151 citations

Viral persistence

1989 • 148 citations

Molecular anatomy of viral persistence

1991 • 148 citations

Monoclonal Antibody for Rapid Laboratory Detection of Cytomegalovirus Infections: Characterization and Diagnostic Application

1985 • 143 citations

The HCMV Gene Products US11 and US2 Differ in Their Ability to Attack Allelic Forms of Murine Major Histocompatibility Complex (MHC) Class I Heavy Chains

1997 • 138 citations

Human cytomegalovirus‐specific cytotoxic T lymphocytes: requirements for in vitro generation and specificity

1983 • 131 citations

Selective interference with class I major histocompatibility complex presentation of the major immediate-early protein following infection with human cytomegalovirus

1993 • 119 citations

Sequence of the short unique region, short repeats, and part of the long repeats of human cytomegalovirus

1986 • 114 citations

Down-regulation of the class I HLA heterodimer and beta2-microglobulin on the surface of cells infected with cytomegalovirus

1992 • 111 citations

E3 Transcription Unit of Adenovirus

1995 • 111 citations

An enhancer element in the short unique region of human cytomegalovirus regulates the production of a group of abundant immediate early transcripts

1988 • 110 citations

Association of human class I MHC alleles with the adenovirus E3/19K protein.

1994 • 108 citations

Human Cytomegalovirus Inhibits Peptide Translocation into the Endoplasmic Reticulum for MHC Class I Assembly

1996 • 101 citations

Use of Recombinant Plasmids to Investigate the Structure of the Human Cytomegalovirus Genome

1982 • 99 citations

Human cytomegalovirus-infected cells have unstable assembly of major histocompatibility complex class I complexes and are resistant to lysis by cytotoxic T lymphocytes

1994 • 92 citations

Human cytomegalovirus UL36-38 and US3 immediate-early genes: temporally regulated expression of nuclear, cytoplasmic, and polysome-associated transcripts during infection

1991 • 89 citations

Identification of the mouse cytomegalovirus genomic region affecting major histocompatibility complex class I molecule transport

1995 • 87 citations

A cluster of dispensable genes within the human cytomegalovirus genome short component: IRS1, US1 through US5, and the US6 family

1992 • 87 citations

Getting the inside out: the transporter associated with antigen processing (TAP) and the presentation of viral antigen.

1995 • 81 citations

How Dna Viruses Perturb Functional Mhc Expression To Alter Immune Recognition

1994 • 72 citations

Down-regulation of the Surface Expression of Class I MHC Antigens by Human Cytomegalovirus

1993 • 72 citations

The Sec61 complex is essential for the insertion of proteins into the membrane of the endoplasmic reticulum

1995 • 63 citations

Fine mapping of transcripts expressed from the US6 gene family of human cytomegalovirus strain AD169

1991 • 62 citations

Replacement mutagenesis of the human cytomegalovirus genome: US10 and US11 gene products are nonessential

1991 • 62 citations

Down-regulation of HLA antigens by the adenovirus type 2 E3/19K protein in a T-lymphoma cell line

1994 • 47 citations

Therapeutic Reconstitution of Human Viral Immunity by Adoptive Transfer of Cytotoxic T Lymphocyte Clones

1994 • 47 citations

Different rates of HLA class I molecule assembly which are determined by amino acid sequence in the ?2 domain

1993 • 47 citations

Proteolytic activity of human cytomegalovirus UL80 protease cleavage site mutants

1994 • 46 citations

Down-regulation of major histocompatibility complex class I synthesis by murine cytomegalovirus early gene expression

1994 • 45 citations

A 15-kilobase-pair region of the human cytomegalovirus genome which includes US1 through US13 is dispensable for growth in cell culture

1991 • 40 citations