PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis

Wound Healing--Aiming for Perfect Skin Regeneration

1997 • 4,630 citations

‘Green mice’ as a source of ubiquitous green cells

1997 • 2,586 citations

Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor

1999 • 2,386 citations

The role of the macrophage in wound repair. A study with hydrocortisone and antimacrophage serum.

1975 • 1,445 citations

Wound Macrophages Express TGF-α and Other Growth Factors in Vivo: Analysis by mRNA Phenotyping

1988 • 1,107 citations

Barriers to Drug Delivery in Solid Tumors

1994 • 1,064 citations

Inhibition of lymphangiogenesis with resulting lymphedema in transgenic mice expressing soluble VEGF receptor-3

2001 • 759 citations

PDGF-C is a new protease-activated ligand for the PDGF α-receptor

2000 • 612 citations

A model for gene therapy of human hereditary lymphedema

2001 • 585 citations

Localization of PDGF-B Protein in Macrophages in All Phases of Atherogenesis

1990 • 584 citations

Role of platelet‐derived growth factor in wound healing

1991 • 569 citations

PDGF-D is a specific, protease-activated ligand for the PDGF β-receptor

2001 • 542 citations

A tumor-homing peptide with a targeting specificity related to lymphatic vessels

2002 • 478 citations

Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors.

2001 • 444 citations

Platelet-derived growth factor: purification and partial characterization.

1979 • 436 citations

Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy.

2002 • 431 citations

PDGF-D, a new protease-activated growth factor

2001 • 389 citations

Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice.

1989 • 365 citations

Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes.

1990 • 263 citations

Injury induces in vivo expression of platelet-derived growth factor (PDGF) and PDGF receptor mRNAs in skin epithelial cells and PDGF mRNA in connective tissue fibroblasts.

1991 • 220 citations

Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis

2000 • 218 citations

Interstitial fluid pressure in rats measured with a modified wick technique

1977 • 191 citations

Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain

2000 • 180 citations

Lymphangiogenic Gene Therapy With Minimal Blood Vascular Side Effects

2002 • 166 citations

PDGF-D is a potent transforming and angiogenic growth factor

2003 • 155 citations

A novel physiological function for platelet‐derived growth factor‐BB in rat dermis.

1996 • 135 citations

Chromosomal Location, Exon Structure, and Vascular Expression Patterns of the Human PDGFC and PDGFD Genes

2001 • 132 citations

Tumor necrosis factor alpha-induced leukocyte adhesion in normal and tumor vessels: effect of tumor type, transplantation site, and host strain.

1995 • 127 citations

Tissue localization of beta receptors for platelet-derived growth factor and platelet-derived growth factor B chain during wound repair in humans.

1993 • 118 citations

Lowering of tumor interstitial fluid pressure specifically augments efficacy of chemotherapy

2003 • 115 citations

VEGFR-2-specific ligand VEGF-E induces non-edematous hyper-vascularization in mice

2003 • 97 citations

A Fully Human Monoclonal Antibody (CR002) Identifies PDGF-D as a Novel Mediator of Mesangioproliferative Glomerulonephritis

2003 • 95 citations

A Potential Oncogenic Activity of Platelet-Derived Growth Factor D in Prostate Cancer Progression

2004 • 93 citations

Primary Structure, Developmental Expression, and Immunolocalization of the Murine Laminin α4 Chain

1997 • 90 citations

Platelet-derived growth factor D: tumorigenicity in mice and dysregulated expression in human cancer.

2002 • 67 citations

Evaluation of methodologies for measurement of interstitial fluid pressure (Pi): physiological implications of recent Pi data.

1990 • 53 citations

Suppression of Keratin 15 Expression by Transforming Growth Factor β in Vitro and by Cutaneous Injury in Vivo

2000 • 49 citations

Molecular Cloning of a Novel Macrophage Maturation-Associated Transcript Encoding a Protein with Several Potential Transmembrane Domains

1995 • 47 citations

PDGF C Is A Selective α Platelet-Derived Growth Factor Receptor Agonist That Is Highly Expressed in Platelet α Granules and Vascular Smooth Muscle

2004 • 46 citations

Double target for tumor mass destruction

2003 • 45 citations

Platelet-Derived Growth Factor B-Chain of Hematopoietic Origin Is Not Necessary for Granulation Tissue Formation and Its Absence Enhances Vascularization

2001 • 23 citations