Platelet-Derived Growth Factor B-Chain of Hematopoietic Origin Is Not Necessary for Granulation Tissue Formation and Its Absence Enhances Vascularization

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

1997 • 2,136 citations

The biology of platelet-derived growth factor

1986 • 2,036 citations

Role of PDGF-B and PDGFR-β in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse

1999 • 1,618 citations

Blood Vessel Formation: What Is Its Molecular Basis?

1996 • 1,242 citations

A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF

1998 • 1,239 citations

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities.

1994 • 1,123 citations

Lack of Pericytes Leads to Endothelial Hyperplasia and Abnormal Vascular Morphogenesis

2001 • 1,067 citations

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

1994 • 984 citations

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture.

1989 • 914 citations

PDGF, TGF-β, and Heterotypic Cell–Cell Interactions Mediate Endothelial Cell–induced Recruitment of 10T1/2 Cells and Their Differentiation to a Smooth Muscle Fate

1998 • 789 citations

A significant part of macrophage-derived growth factor consists of at least two forms of PDGF

1985 • 719 citations

PDGF and FGF stimulate wound healing in the genetically diabetic mouse.

1990 • 689 citations

Two Different Subunits Associate to Create Isoform-Specific Platelet-derived Growth Factor Receptors

1989 • 633 citations

PDGF-C is a new protease-activated ligand for the PDGF α-receptor

2000 • 612 citations

Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells.

1987 • 607 citations

Localization of PDGF-B Protein in Macrophages in All Phases of Atherogenesis

1990 • 584 citations

PDGF-D is a specific, protease-activated ligand for the PDGF β-receptor

2001 • 542 citations

Endothelial Cells of Hematopoietic Origin Make a Significant Contribution to Adult Blood Vessel Formation

2000 • 524 citations

Cultured endothelial cells produce a platelet-derived growth factor-like protein

1983 • 507 citations

PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors.

1994 • 428 citations

PDGF-D, a new protease-activated growth factor

2001 • 389 citations

Developmental roles of platelet‐derived growth factors

2001 • 365 citations

Platelet‐derived growth factor is a chemoattractant for vascular smooth muscle cells

1982 • 340 citations

Endothelial Cells Modulate the Proliferation of Mural Cell Precursors via Platelet-Derived Growth Factor-BB and Heterotypic Cell Contact

1999 • 338 citations

Vascular endothelial growth factor, platelet-derived growth factor, and insulin-like growth factor-1 promote rat aortic angiogenesis in vitro.

1994 • 297 citations

Stimulation of granulation tissue formation by platelet-derived growth factor in normal and diabetic rats.

1985 • 277 citations

Platelet-Derived Growth Factor is AngiogenicIn Vivo

1992 • 276 citations

In vivo incisional wound healing augmented by platelet-derived growth factor and recombinant c-sis gene homodimeric proteins.

1988 • 249 citations

Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB.

1993 • 238 citations

Sera and conditioned media contain different isoforms of platelet-derived growth factor (PDGF) which bind to different classes of PDGF receptor

1989 • 216 citations

The Effects of Platelet-Derived Growth Factor in Cultured Microvessel Endothelial Cells*

1989 • 137 citations

Chromosomal Location, Exon Structure, and Vascular Expression Patterns of the Human PDGFC and PDGFD Genes

2001 • 132 citations

Strain-Dependent Vascular Remodeling Phenotypes in Inbred Mice

2000 • 127 citations

Chimaeric analysis reveals role of Pdgf receptors in all muscle lineages

1998 • 117 citations

Basis of hematopoietic defects in platelet-derived growth factor (PDGF)-B and PDGF β-receptor null mice

2001 • 75 citations

Vascular Remodeling in Response to Altered Blood Flow Is Mediated by Fibroblast Growth Factor-2

1999 • 72 citations

Expression of platelet-derived growth factor and its receptors in the developing and adult mouse kidney

1998 • 57 citations

Three Isoforms of Platelet-Derived Growth Factors All Have the Capability to Induce Angiogenesis in Vivo.

1994 • 47 citations

Chimera Analysis Reveals That Fibroblasts and Endothelial Cells Require Platelet-Derived Growth Factor Receptorβ Expression for Participation in Reactive Connective Tissue Formation in Adults but Not during Development

1999 • 44 citations

Platelet-Derived Growth Factor β-Receptors Can Both Promote and Inhibit Chemotaxis in Human Vascular Smooth Muscle Cells

1997 • 37 citations