PDGF-C is a new protease-activated ligand for the PDGF α-receptor

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor

1999 • 2,386 citations

Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

1997 • 2,136 citations

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities.

1994 • 1,123 citations

The vascular endothelial growth factor (VEGF) isoforms: differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF.

1993 • 1,114 citations

Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

1994 • 984 citations

PDGF-A Signaling Is a Critical Event in Lung Alveolar Myofibroblast Development and Alveogenesis

1996 • 867 citations

Vascular endothelial growth factor B, a novel growth factor for endothelial cells.

1996 • 788 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

1997 • 782 citations

Signal transduction via platelet-derived growth factor receptors

1998 • 735 citations

The PDGFα receptor is required for neural crest cell development and for normal patterning of the somites

1997 • 706 citations

A versatilein vivoandin vitroeukaryotic expression vector for protein engineering

1988 • 686 citations

The CUB Domain

1993 • 564 citations

Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.

1988 • 514 citations

Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice.

1991 • 479 citations

Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice

1999 • 430 citations

Paracrine PDGF-B/PDGF-Rβ signaling controls mesangial cell development in kidney glomeruli

1998 • 359 citations

Neuropilin-2 Is a Receptor for Semaphorin IV Insight into the Structural Basis of Receptor Function and Specificity

1998 • 352 citations

Neuropilin-1 Extracellular Domains Mediate Semaphorin D/III-Induced Growth Cone Collapse

1998 • 269 citations

Autocrine Stimulation of Intracellular PDGF Receptors in v- sis -Transformed Cells

1988 • 267 citations

PDGF alpha- and beta-receptors activate unique and common signal transduction pathways.

1992 • 259 citations

The Intrinsic Factor-Vitamin B12 Receptor and Target of Teratogenic Antibodies Is a Megalin-binding Peripheral Membrane Protein with Homology to Developmental Proteins

1998 • 254 citations

A Heparin-Binding Form of Placenta Growth Factor (PlGF-2) is Expressed in Human Umbilical Vein Endothelial Cells and in Placenta

1993 • 245 citations

Coexpression of a PDGF-like growth factor and PDGF receptors in a human osteosarcoma cell line: Implications for autocrine receptor activation

1984 • 238 citations

Crystal structure of human platelet-derived growth factor BB.

1992 • 232 citations

Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle

1999 • 228 citations

Structure, Expression and Receptor-Binding Properties of Novel Vascular Endothelial Growth Factors

1999 • 170 citations

Inductive Tissue Interactions, Cell Signaling, and the Control of Kidney Organogenesis

1997 • 137 citations

Molecular Dissection of the Intrinsic Factor-Vitamin B12 Receptor, Cubilin, Discloses Regions Important for Membrane Association and Ligand Binding

1999 • 129 citations

Expression of Three Recombinant Homodimeric Isoforms of PDGF inSaccharomyces cerevisiae: Evidence for Difference in Receptor Binding and Functional Activities

1989 • 126 citations

PDGF-AA and PDGF-BB biosynthesis: proprotein processing in the Golgi complex and lysosomal degradation of PDGF-BB retained intracellularly.

1992 • 85 citations

Distribution and Functions of Platelet-Derived Growth Factors and Their Receptors during Embryogenesis

1997 • 76 citations

Role of Platelet-Derived Growth Factors in Angiogenesis and Alveogenesis

1999 • 75 citations

Not all myofibroblasts are alike

1998 • 59 citations

Characterization of the retention motif in the C-terminal part of the long splice form of platelet-derived growth factor A-chain.

1994 • 59 citations

Complement components C1r/C1s, bone morphogenic protein 1 and Xenopus laevis developmentally regulated protein UVS.2 share common repeats

1991 • 47 citations

Identification of a hydrophobic region in the carboxyl terminus of the platelet-derived growth factor beta-receptor which is important for ligand-mediated endocytosis.

1991 • 46 citations

Mitogenic effect of PDGF-AA on cardiac fibroblasts

1998 • 32 citations

Structure and functions of the interaction domains of C1r and C1s: keystones of the architecture of the C1 complex

1999 • 28 citations

Differences in Binding to the Solid Substratum and Extracellular Matrix may Explain Isoform-Specific Paracrine Effects of Platelet-Derived Growth Factor

1994 • 13 citations