Tissue localization of beta receptors for platelet-derived growth factor and platelet-derived growth factor B chain during wound repair in humans.

The biology of platelet-derived growth factor

1986 • 2,036 citations

PLATELET-DERIVED GROWTH FACTOR

1989 • 967 citations

Migration and maturation of Langerhans cells in skin transplants and explants.

1990 • 663 citations

Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells.

1987 • 607 citations

Two Classes of PDGF Receptor Eecognize Different Isoforms of PDGF

1988 • 603 citations

Localization of PDGF-B Protein in Macrophages in All Phases of Atherogenesis

1990 • 584 citations

Ulex europaeus I lectin as a marker for vascular endothelium in human tissues.

1982 • 573 citations

Binding of different dimeric forms of PDGF to human fibroblasts: evidence for two separate receptor types.

1988 • 514 citations

Platelet-derived growth factor: mechanism of action and possible in vivo function.

1990 • 491 citations

Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization.

1988 • 481 citations

Role of platelet-derived growth factor in wound healing: synergistic effects with other growth factors.

1987 • 421 citations

PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model

1991 • 410 citations

Platelet-derived growth factor BB for the treatment of chronic pressure ulcers

1992 • 389 citations

PDGF A-chain gene is expressed by mammalian neurons during development and in maturity

1991 • 360 citations

cDNA cloning and expression of a human platelet-derived growth factor (PDGF) receptor specific for B-chain-containing PDGF molecules.

1988 • 338 citations

Platelet-derived growth factor (BB homodimer), transforming growth factor-beta 1, and basic fibroblast growth factor in dermal wound healing. Neovessel and matrix formation and cessation of repair.

1992 • 336 citations

β1 Integrin-mediated collagen gel contraction is stimulated by PDGF

1990 • 266 citations

Differential effects of the various isoforms of platelet-derived growth factor on chemotaxis of fibroblasts, monocytes, and granulocytes.

1990 • 263 citations

PDGF alpha- and beta-receptors activate unique and common signal transduction pathways.

1992 • 259 citations

In vivo incisional wound healing augmented by platelet-derived growth factor and recombinant c-sis gene homodimeric proteins.

1988 • 249 citations

INDUCTION OF B-TYPE RECEPTORS FOR PLATELET-DERIVED GROWTH FACTOR IN VASCULAR INFLAMMATION: POSSIBLE IMPLICATIONS FOR DEVELOPMENT OF VASCULAR PROLIFERATIVE LESIONS

1988 • 247 citations

Platelet isoforms of platelet-derived growth factor stimulate fibroblasts to contract collagen matrices.

1989 • 224 citations

Neurotrophic activity of platelet-derived growth factor (PDGF): Rat neuronal cells possess functional PDGF beta-type receptors and respond to PDGF.

1991 • 222 citations

Differential expression of markers for endothelial cells, pericytes, and basal lamina in the microvasculature of tumors and granulation tissue.

1991 • 222 citations

Injury induces in vivo expression of platelet-derived growth factor (PDGF) and PDGF receptor mRNAs in skin epithelial cells and PDGF mRNA in connective tissue fibroblasts.

1991 • 220 citations

Discrimination of Human Macrophages and Dendritic Cells by Means of Monoclonal Antibodies

1986 • 199 citations

Immunohistologic Demonstration of Platelet-derived Growth Factor (PDGF) and sis-Oncogene Expression in Scleroderma

1989 • 173 citations

Effect of receptor kinase inactivation on the rate of internalization and degradation of PDGF and the PDGF beta-receptor.

1991 • 166 citations

Rat Brain Capillary Endothelial Cells Express Functional PDGF B-Type Receptors

1989 • 153 citations

Platelet-derived growth factor receptors in the kidney—Upregulated expression in inflammation

1989 • 141 citations

The Effects of Platelet-Derived Growth Factor in Cultured Microvessel Endothelial Cells*

1989 • 137 citations

Induction of platelet-derived growth factor receptor expression in smooth muscle cells and fibroblasts upon tissue culturing.

1988 • 135 citations

Wound repair

1989 • 112 citations

Current Concepts in Wound Healing Growth Factor and Macrophage Interaction

1990 • 111 citations

Platelet-derived growth factor and IL-1 interactions in rheumatoid arthritis. Regulation of synoviocyte proliferation, prostaglandin production, and collagenase transcription.

1989 • 101 citations

Increased Expression of N-myc in Human Small Cell Lung Cancer Biopsies Predicts Lack of Response to Chemotherapy and Poor Prognosis

1987 • 96 citations

Expression of Platelet‐Derived Growth Factor Receptors is Induced on Connective Tissue Cells During Chronic Synovial Inflammation

1988 • 94 citations

Monoclonal antibodies with exclusive reactivity against parathyroid cells and tubule cells of the kidney.

1987 • 79 citations

Expression of platelet-derived growth factor beta-receptors on stromal tissue cells in human carcinoid tumors.

1990 • 79 citations

Production of platelet derived growth factor B chain (PDGF-B/c-sis) mRNA and immunoreactive PDGF B-like polypeptide by rheumatoid synovium: coexpression with heparin binding acidic fibroblast growth factor-1.

1991 • 77 citations

Schwann Cells Secrete a PDGF‐like Factor: Evidence for an Autocrine Growth Mechanism involving PDGF

1990 • 77 citations

cDNA Cloning and Expression of a Human Platelet-Derived Growth Factor (PDGF) Receptor Specific for B-Chain-Containing PDGF Molecules

1988 • 76 citations

Characterization of two monoclonal antibodies reactive with the external domain of the platelet-derived growth factor receptor.

1988 • 68 citations

Effects of homodimeric isoforms of platelet-derived growth factor (PDGF-AA and PDGF-BB) on wound healing in rat

1992 • 62 citations

Radioimmunoassay of human platelet-derived growth factor using monoclonal antibody toward a synthetic 73–97 fragment of its B-chain

1989 • 55 citations

Wounds and wound healing

1988 • 48 citations

Expression of platelet-derived growth factor-beta receptors on human fibroblasts. Regulation by recombinant platelet-derived growth factor-BB, IL-1, and tumor necrosis factor-alpha.

1992 • 30 citations

Radioimmunoassay of Human Platelet-Derived Growth Factor Using Monoclonal Antibody Toward a Synthetic 73-97 Fragment of its B-Chain

1989 • 12 citations

Perivascular Dendritic Macrophages as Immunobiological Constituents of the Human Dermal Microvascular Unit.

1989 • 5 citations