A highly conserved lysine residue on the head domain of type II keratins is essential for the attachment of keratin intermediate filaments to the cornified cell envelope through isopeptide crosslinking by transglutaminases

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Laboratory techniques in biochemistry and molecular biology

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Epidermal Lipids, Barrier Function, and Desquamation

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Transglutaminases: multifunctional cross‐linking enzymes that stabilize tissues

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The cornified envelope of terminally differentiated human epidermal keratinocytes consists of cross-linked protein

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The Proteins Elafin, Filaggrin, Keratin Intermediate Filaments, Loricrin, and Small Proline-rich Proteins 1 and 2 Are Isodipeptide Cross-linked Components of the Human Epidermal Cornified Cell Envelope

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Laboratory techniques in biochemistry and molecular biology

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Studies on Contact Sensitivity to Chromium in the Guinea Pig. The Role of Valence in the Formation of the Antigenic Determinant

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Evidence That the Corneocyte Has a Chemically Bound Lipid Envelope

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Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins.

1991 • 305 citations

A leucine→proline mutation in the H1 subdomain of keratin 1 causes epidermolytic hyperkeratosis

1992 • 284 citations

Making a connection: direct binding between keratin intermediate filaments and desmosomal proteins.

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Desmosomes and Hemidesmosomes: Constitutive Molecular Components

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Keratin Intermediate Filament Structure

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Protein composition of cornified cell envelopes of epidermal keratinocytes

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Direct Evidence That Involucrin Is a Major Early Isopeptide Cross-linked Component of the Keratinocyte Cornified Cell Envelope

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Cornified Cell Envelope

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THE CYTOSKELETON AND DISEASE: Genetic Disorders of Intermediate Filaments

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Biochemical, Structural, and Transglutaminase Substrate Properties Of Human Loricrin, the Major Epidermal Cornified Cell Envelope Protein

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Two-hybrid Analysis Reveals Fundamental Differences in Direct Interactions between Desmoplakin and Cell Type-specific Intermediate Filaments

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[20] Removal of sodium dodecyl sulfate from proteins by ion-pair extraction

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A Mutation in the V1 End Domain of Keratin 1 in Non-Epidermolytic Palmar-Plantar Keratoderma

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Characterization of human cytokeratin 2, an Epidermal cytoskeletal protein synthesized late during differentiation

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Protransglutaminase E from guinea pig skin. Isolation and partial characterization.

1990 • 110 citations

The Cornified Envelope: A Key Structure of Terminally Differentiating Keratinocytes

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A model for the hierarchical structure of the human epidermal cornified cell envelope.

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The Stratum Corneum Revisited

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The structure of the transglutaminase 1 enzyme. Deletion cloning reveals domains that regulate its specific activity and substrate specificity.

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The molecular biology of desmosomes and hemidesmosomes: ′What's in a name?'

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Analysis of the mechanism of assembly of mouse keratin 1/keratin 10 intermediate filaments in vitro suggests that intermediate filaments are built from multiple oligomeric units rather than a unique tetrameric building block

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N 1 N 8-bis(γ-glutamyl)spermidine cross-linking in epidermal-cell envelopes. Comparison of cross-link levels in normal and psoriatic cell envelopes

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Molecular Biology of Desmosomes and Hemidesmosomes

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Are CD4 and Fas peptide identities of gp120 relevant to the molecular basis of AIDS pathogenesis?

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