Characterization of human cytokeratin 2, an Epidermal cytoskeletal protein synthesized late during differentiation

Methods in Enzymology , Vol

1966 • 26,261 citations

The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells

1982 • 5,272 citations

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

1988 • 4,008 citations

Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes

1984 • 1,638 citations

MOLECULAR AND CELLULAR BIOLOGY OF INTERMEDIATE FILAMENTS

1988 • 1,395 citations

Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells.

1986 • 1,378 citations

Changes in keratin gene expression during terminal differentiation of the keratinocyte

1980 • 1,059 citations

Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies

1982 • 777 citations

Regulation of terminal differentiation of cultured human keratinocytes by vitamin A

1981 • 756 citations

Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications, and limitations.

1985 • 735 citations

Diversity of cytokeratins

1981 • 611 citations

Plakoglobin: A protein common to different kinds of intercellular adhering junctions

1986 • 508 citations

Antibody to prekeratin

1978 • 496 citations

Patterns of Expression and Organization of Cytokeratin Intermediate Filaments

1985 • 420 citations

Immunofluorescent staining of keratin fibers in cultured cells

1978 • 375 citations

Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns.

1990 • 375 citations

Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation.

1988 • 359 citations

Pair formation and promiscuity of cytokeratins: formation in vitro of heterotypic complexes and intermediate-sized filaments by homologous and heterologous recombinations of purified polypeptides.

1985 • 343 citations

Retinoids as important regulators of terminal differentiation: examining keratin expression in individual epidermal cells at various stages of keratinization.

1987 • 343 citations

The cDNA sequence of a type II cytoskeletal keratin reveals constant and variable structural domains among keratins

1983 • 326 citations

The cDNA sequence of a human epidermal keratin: Divergence of sequence but conservation of structure among intermediate filament proteins

1982 • 298 citations

Different keratin polypeptides in epidermis and other epithelia of human skin: a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas.

1982 • 278 citations

Cellular and Molecular Biology of Intermediate Filaments

1990 • 262 citations

The role of keratin subfamilies and keratin pairs in the formation of human epidermal intermediate filaments.

1986 • 259 citations

Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles

1988 • 251 citations

Cytoskeletal components of lymphoid organs

1987 • 234 citations

Changes in the Pattern of Cytokeratin Polypeptides in Epidermis and Hair Follicles During Skin Development in Human Fetuses

1982 • 230 citations

Structure of intermediate filaments

1983 • 195 citations

Heterotypic tetramer (A2D2) complexes of non-epidermal keratins isolated from cytoskeletons of rat hepatocytes and hepatoma cells

1984 • 194 citations

A subfamily of relatively large and basic cytokeratin polypeptides as defined by peptide mapping is represented by one or several polypeptides in epithelial cells.

1982 • 186 citations

Amino acid sequences of mouse and human epidermal type II keratins of Mr 67,000 provide a systematic basis for the structural and functional diversity of the end domains of keratin intermediate filament subunits.

1985 • 183 citations

Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis.

1988 • 182 citations

Sequential expression of mRNA-encoded keratin sets in neonatal mouse epidermis: Basal cells with properties of terminally differentiating cells

1984 • 168 citations

Evidence for posttranscriptional regulation of the keratins expressed during hyperproliferation and malignant transformation in human epidermis.

1986 • 164 citations

Differentiation-related changes of cytokeratin expression in cultured keratinocytes and in fetal, newborn, and adult epidermis

1987 • 159 citations

The use of retinoic acid to probe the relation between hyperproliferation-associated keratins and cell proliferation in normal and malignant epidermal cells.

1989 • 155 citations

Differences of expression of cytokeratin polypeptides in various epithelial skin tumors

1984 • 145 citations

Low level expression of cytokeratins 8, 18 and 19 in vascular smooth muscle cells of human umbilical cord and in cultured cells derived therefrom, with an analysis of the chromosomal locus containing the cytokeratin 19 gene.

1988 • 141 citations

Identification of a basic protein of Mr 75,000 as an accessory desmosomal plaque protein in stratified and complex epithelia.

1988 • 138 citations

Chapter 5 Patterns of Keratin Expression Define Distinct Pathways of Epithelial Development and Differentiation

1987 • 138 citations

Chapter 2 The Human Keratin Genes and Their Differential Expression

1987 • 126 citations

Cytokeratin expression in simple epithelia

1986 • 124 citations

Cytokeratin No. 9, an epidermal type I keratin characteristic of a special program of keratinocyte differentiation displaying body site specificity.

1986 • 119 citations

Cytokeratin patterns of human oral epithelia: Differences in cytokeratin synthesis in gingival epithelium and the adjacent alveolar mucosa

1985 • 118 citations

Proteolytic modification of acidic and basic keratins during terminal differentiation of mouse and human epidermis

1984 • 116 citations

Mesenchyme-mediated and endogenous regulation of growth and differentiation of human skin keratinocytes derived from different body sites

1990 • 110 citations

Extensive changes in cytokeratin expression patterns in pathologically affected human gingiva

1989 • 102 citations

The organization of cytokeratin filaments in the intestinal epithelium.

1979 • 97 citations

Squamous cell metaplasia in the human lung: molecular characteristics of epithelial stratification

1992 • 89 citations

De novo synthesis and specific assembly of keratin filaments in nonepithelial cells after microinjection of mRNA for epidermal keratin

1983 • 89 citations

Chapter 3 Expression and Modification of Keratins During Terminal Differentiation of Mammalian Epidermis

1987 • 81 citations

Cytokeratin domains involved in heterotypic complex formation determined by in-vitro binding assays

1987 • 74 citations

Translational products of mRNAs coding for non-epidermal cytokeratins.

1983 • 71 citations

Evolution of keratin genes: Different protein domains evolve by different pathways

1987 • 67 citations

Cell culture of mammalian thymic epithelial cells: Growth, structural, and antigenic properties

1984 • 66 citations

Amino acid sequence diversity between bovine epidermal cytokeratin polypeptides of the basic (type II) subfamily as determined from cDNA clones

1984 • 64 citations

Polymorphic Keratins in Human Epidermis

1987 • 64 citations

Structural studies on the microfibrillar proteins of wool. Interaction between α-helical segments and reassembly of a four-chain structure

1983 • 62 citations

Cell type-specific expression of bovine keratin genes as demonstrated by the use of complementary DNA clones

1984 • 60 citations

Distribution of a special subset of keratinocytes characterized by the expression of cytokeratin 9 in adult and fetal human epidermis of various body sites

1987 • 58 citations

Concerted gene duplications in the two keratin gene families

1988 • 53 citations

Synthesis of cytokeratin 13, a component characteristic of internal stratified epithelia, is not induced in human epidermal tumors

1989 • 49 citations

An unusual type-II 70-kilodalton keratin protein of mouse epidermis exhibiting postnatal body-site specificity and sensitivity to hyperproliferation

1987 • 27 citations