The molecular biology of desmosomes and hemidesmosomes: ′What's in a name?'

Structure and Function of Intercellular Junctions

1974 • 1,339 citations

CADHERINS: A MOLECULAR FAMILY IMPORTANT IN SELECTIVE CELL-CELL ADHESION

1990 • 1,293 citations

Epiligrin, a new cell adhesion ligand for integrin α3β1 in epithelial basement membranes

1991 • 771 citations

Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments.

1991 • 755 citations

Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.

1991 • 574 citations

Plakoglobin: A protein common to different kinds of intercellular adhering junctions

1986 • 508 citations

Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes.

1990 • 486 citations

Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)

1991 • 481 citations

FINE STRUCTURE OF DESMOSOMES, HEMIDESMOSOMES, AND AN ADEPIDERMAL GLOBULAR LAYER IN DEVELOPING NEWT EPIDERMIS

1966 • 450 citations

Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels

1991 • 394 citations

Identification of a cadherin cell adhesion recognition sequence

1990 • 382 citations

Isolation of complementary DNA for bullous pemphigoid antigen by use of patients' autoantibodies.

1988 • 369 citations

Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules.

1990 • 327 citations

Epithelial integrin alpha 6 beta 4: complete primary structure of alpha 6 and variant forms of beta 4.

1990 • 323 citations

Demonstration of an Adhering-Junction Molecule (Plakoglobin) in the Autoantigens of Pemphigus Foliaceus and Pemphigus Vulgaris

1989 • 280 citations

Desmosomes and Hemidesmosomes: Constitutive Molecular Components

1990 • 280 citations

Cloning and sequence analysis of beta-4 cDNA: an integrin subunit that contains a unique 118 kd cytoplasmic domain.

1990 • 278 citations

Structure of the human desmoplakins. Implications for function in the desmosomal plaque.

1990 • 275 citations

A Pool of Bullous Pemphigoid Antigen(s) Is Intracellular and Associated with the Basal Cell Cytoskeleton-Hemidesmosome Complex

1985 • 250 citations

Amino acid sequence of a novel integrin beta 4 subunit and primary expression of the mRNA in epithelial cells.

1990 • 249 citations

A function for the integrin alpha 6 beta 4 in the hemidesmosome.

1991 • 225 citations

The α6β1 (VLA-6) and α6β4 protein complexes: tissue distribution and biochemical properties

1990 • 219 citations

Cloning and sequencing of rat plectin indicates a 466-kD polypeptide chain with a three-domain structure based on a central alpha-helical coiled coil.

1991 • 188 citations

Cloning and sequence analysis of desmosomal glycoproteins 2 and 3 (desmocollins): cadherin-like desmosomal adhesion molecules with heterogeneous cytoplasmic domains.

1991 • 188 citations

Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules.

1991 • 185 citations

Antibodies to High Molecular Weight Polypeptides of Desmosomes: Specific Localization of a Class of Junctional Proteins in Cells and Tissues

1981 • 181 citations

Bullous Pemphigoid Antigen Localization Suggests an Intracellular Association with Hemidesmosomes

1985 • 178 citations

Antibodies to epithelial desmosomes show wide tissue and species cross-reactivity

1983 • 160 citations

Immunochemical characterization of three components of the hemidesmosome and their expression in cultured epithelial cells.

1989 • 152 citations

Production of Rabbit Antibodies Against Carboxy-Terminal Epitopes Encoded by Bullous Pemphigoid cDNA

1990 • 144 citations

Identification of desmosomal surface components (desmocollins) and inhibition of desmosome formation by specific fab′

1984 • 142 citations

Identification of two collagen domains within the bullous pemphigoid autoantigen, BP180.

1991 • 139 citations

Identification of a basic protein of Mr 75,000 as an accessory desmosomal plaque protein in stratified and complex epithelia.

1988 • 138 citations

The cell in contact: Adhesions and junctions as morphogenetic determinants

1986 • 136 citations

Structural analysis and expression of human desmoglein: a cadherin-like component of the desmosome

1991 • 131 citations

Electronmicrograms of larval amphibian epidermis

1954 • 122 citations

Desmosome biogenesis in the mouse preimplantation embryo

1991 • 122 citations

Desmosomal glycoproteins II and III. Cadherin-like junctional molecules generated by alternative splicing

1991 • 120 citations

Desmocollins form a distinct subset of the cadherin family of cell adhesion molecules.

1991 • 107 citations

Desmoplakin I and desmoplakin II

1989 • 105 citations

The new basement membrane antigen recognized by the monoclonal antibody GB3 is a large size glycoprotein: modulation of its expression by retinoic acid

1988 • 101 citations

Desmocalmin: a calmodulin-binding high molecular weight protein isolated from desmosomes.

1985 • 99 citations

Localisation of the protein and glycoprotein components of bovine nasal epithelial desmosomes by immunoelectron microscopy.

1987 • 87 citations

ULTRASTRUCTURE OF DESMOSOMES IN MAMMALIAN INTERCALATED DISC; APPEARANCES AFTER LANTHANUM TREATMENT

1969 • 81 citations

Distribution of desmosomal components in the tissues of vertebrates, studied by fluorescent antibody staining

1984 • 77 citations

Biochemical characterization of desmosomal proteins isolated from bovine muzzle epidermis: amino acid and carbohydrate composition.

1985 • 74 citations

A new high molecular mass protein showing unique localization in desmosomal plaque.

1989 • 72 citations

On the Molecular Organization, Diversity and Functions of Desmosomal Proteins

2007 • 72 citations

Early expression of desmosomal components during kidney tubule morphogenesis in human and murine embryos

1990 • 72 citations

Size heterogeneity, phosphorylation and transmembrane organisation of desmosomal glycoproteins 2 and 3 (desmocollins) in MDCK cells

1990 • 64 citations

A novel hemidesmosomal plaque component: Tissue distribution and incorporation into assembling hemidesmosomes in an in Vitro model

1991 • 63 citations

Amino acid sequence of bovine muzzle epithelial desmocollin derived from cloned cDNA: A novel subtype of desmosomal cadherins

1991 • 62 citations

Mouse antisera specific for desmosomal adhesion molecules of suprabasal skin cells, meninges, and meningioma.

1986 • 59 citations

A cell surface desmosome-associated component: identification of tissue-specific cell adhesion molecule.

1986 • 57 citations

Detection and Partial Characterization o f A Midlamina Lucida-Hemidesmosome-Associated Antigen (19-DEJ-1) Present Within Human Skin

1989 • 53 citations

Is the hemidesmosome a half desmosome? An immunological comparison of mammalian desmosomes and hemidesmosomes

1986 • 49 citations

A protein antigenically related to nuclear lamin B mediates the association of intermediate filaments with desmosomes.

1990 • 46 citations

Keratinization is associated with the expression of a new protein related to the desmosomal cadherins DGII/III

1991 • 28 citations

Evidence for heterogeneity in the 160/165×103mr glycoprotein components of desmosomes

1987 • 27 citations

Mutual desmosome formation between all binary combinations of human, bovine, canine, avian and amphibian cells: desmosome formation is not tissue- or species-specific

1985 • 20 citations

Characterization of keratocalmin, a calmodulin-binding protein from human epidermis.

1991 • 19 citations