Mismatch Repair Mutants in Yeast Are Not Defective in Transcription-Coupled DNA Repair of UV-Induced DNA Damage

[12] One-step gene disruption in yeast

1983 • 3,302 citations

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1993 • 2,884 citations

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1993 • 2,282 citations

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

1994 • 2,071 citations

Mutation of a mutL Homolog in Hereditary Colon Cancer

1994 • 1,834 citations

Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer

1994 • 1,544 citations

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

1987 • 1,235 citations

DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

1985 • 1,233 citations

Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair

1993 • 1,076 citations

MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR

1991 • 876 citations

DNA Repair Helicase: a Component of BTF2 (TFIIH) Basic Transcription Factor

1993 • 795 citations

Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells

1995 • 599 citations

The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.

1990 • 552 citations

GTBP, a 160-Kilodalton Protein Essential for Mismatch-binding Activity in Human Cells

1995 • 528 citations

The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH

1995 • 485 citations

Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II

1994 • 473 citations

Mutations of GTBP in Genetically Unstable Cells

1995 • 471 citations

An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

1993 • 445 citations

The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor.

1994 • 381 citations

Removal of Nonhomologous DNA Ends in Double-Strand Break Recombination: the Role of the Yeast Ultraviolet Repair Gene RAD1

1992 • 375 citations

Defective mismatch binding and a mutator phenotype in cells tolerant to DNA damage

1993 • 361 citations

Transcript cleavage by RNA polymerase II arrested by a cyclobutane pyrimidine dimer in the DNA template.

1994 • 357 citations

Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions.

1992 • 353 citations

Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair

1993 • 317 citations

Mismatch repair: mechanisms and relationship to cancer susceptibility

1995 • 307 citations

Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines.

1995 • 301 citations

Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cells

1993 • 292 citations

Transcription-Coupled Repair Deficiency and Mutations in Human Mismatch Repair Genes

1996 • 289 citations

MLH1, PMS1, and MSH2 Interactions During the Initiation of DNA Mismatch Repair in Yeast

1994 • 287 citations

RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6.

1994 • 246 citations

DNA Repair and Mutagenesis in Yeast

1981 • 242 citations

Dual requirement in yeast DNA mismatch repair for MLH1 and PMS1, two homologs of the bacterial mutL gene.

1994 • 222 citations

MEIOTIC GENE CONVERSION MUTANTS IN SACCHAROMYCES CEREVISIAE. I. ISOLATION AND CHARACTERIZATION OF pms1-1 AND pms1-2

1985 • 220 citations

RAD1 and RAD10, but Not Other Excision Repair Genes, Are Required for Double-Strand Break-Induced Recombination in Saccharomyces cerevisiae

1995 • 217 citations

Repair of DNA heteroduplexes containing small heterologous sequences in Escherichia coli.

1992 • 215 citations

Escherichia coli mfd mutant deficient in "mutation frequency decline" lacks strand-specific repair: in vitro complementation with purified coupling factor.

1991 • 213 citations

Mitotic Crossovers between Diverged Sequences Are Regulated by Mismatch Repair Proteins in Saccharomyces cerevisiae

1996 • 212 citations

Isolation and partial characterization of human cell mutants differing in sensitivity to killing and mutation by methylnitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine.

1986 • 203 citations

The RAD7 and RAD16 genes, which are essential for pyrimidine dimer removal from the silent mating type loci, are also required for repair of the nontranscribed strand of an active gene in Saccharomyces cerevisiae.

1994 • 200 citations

Cloning and nucleotide sequence of DNA mismatch repair gene PMS1 from Saccharomyces cerevisiae: homology of PMS1 to procaryotic MutL and HexB

1989 • 193 citations

Radiation-Sensitive Mutants and Repair in Yeast

1983 • 177 citations

Preferential repair of cyclobutane pyrimidine dimers in the transcribed strand of a gene in yeast chromosomes and plasmids is dependent on transcription.

1992 • 176 citations

Products of DNA mismatch repair genes mutS and mutL are required for transcription-coupled nucleotide-excision repair of the lactose operon in Escherichia coli.

1996 • 174 citations

GENE AND TRANSCRIPTION UNIT MAPPING BY RADIATION EFFECTS

1978 • 172 citations

Transcription preferentially inhibits nucleotide excision repair of the template DNA strand in vitro.

1990 • 170 citations

DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines.

1995 • 168 citations

Binding of Mismatched Microsatellite DNA Sequences by the Human MSH2 Protein

1994 • 166 citations

Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast

1994 • 163 citations

Mutations in the MSH3 gene preferentially lead to deletions within tracts of simple repetitive DNA in Saccharomyces cerevisiae.

1995 • 147 citations

Effects of abasic sites and DNA single-strand breaks on prokaryotic RNA polymerases.

1993 • 143 citations

Structure and Function of Transcription-Repair Coupling Factor

1995 • 114 citations

The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions.

1995 • 106 citations

Double Mutants of Saccharomyces cerevisiae with Alterations in Global Genome and Transcription-Coupled Repair

1996 • 97 citations

Purified human MSH2 protein binds to DNA containing mismatched nucleotides.

1994 • 90 citations

Isolation and characterization of dam+ revertants and suppressor mutations that modify secondary phenotypes of dam-3 strains of Escherichia coli K-12

1980 • 85 citations

N-Methyl-N′-nitro-N-nitrosoguanidine sensitivity of E. coli mutants deficient in DNA methylation and mismatch repair

1981 • 59 citations

The COOH terminus of suppressor of stem loop (SSL2/RAD25) in yeast is essential for overall genomic excision repair and transcription-coupled repair.

1994 • 59 citations

Recombinagenic processing of UV-light photoproducts in nonreplicating phage DNA by the Escherichia coli methyl-directed mismatch repair system.

1991 • 48 citations

Mechanisms And Biological Effects Of Mismatch Repair

1991 • 45 citations

Strand bias in mutation involving 5-methylcytosine deamination in the human hprt gene

1994 • 40 citations

Characterization of a DNA mismatch-binding activity in yeast extracts.

1993 • 34 citations

DNA structures generated during recombination initiated by mismatch repair of UV-irradiated nonreplicating phage DNA in Escherichia coli: requirements for helicase, exonucleases, and RecF and RecBCD functions.

1995 • 33 citations

Nucleotide excision repair in yeast

1994 • 24 citations

DNA mismatch repair mutants do not increase N-methyl-N'-nitro- N-nitrosoguanidine tolerance in O⁶-methylguanine DNA methyltransferase-deficient yeast cells

1995 • 24 citations

Action of intact AP (apurinic/apyrimidinic) sites and AP sites associated with breaks on the transcription of T7 coliphage DNA by Escherichia coli RNA polymerase

1985 • 9 citations

Transcription preferentially inhibits nucleotide excision repair of the template DNA strand in vitro

1990 • 8 citations