Strand bias in mutation involving 5-methylcytosine deamination in the human hprt gene

p53 Mutations in Human Cancers

1991 • 8,133 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene

1987 • 1,235 citations

DNA methylation and the frequency of CpG in animal DNA

1980 • 1,146 citations

The CpG dinucleotide and human genetic disease

1988 • 946 citations

Mutagenic deamination of cytosine residues in DNA

1980 • 761 citations

Heat-induced deamination of cytosine residues in deoxyribonucleic acid

1974 • 725 citations

5-Methylcytosine as an Endogenous Mutagen in the Human LDL Receptor and p53 Genes

1990 • 643 citations

The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.

1990 • 552 citations

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.

1990 • 408 citations

Apurinic sites as mutagenic intermediates

1985 • 283 citations

Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells.

1990 • 253 citations

Different base/base mispairs are corrected with different efficiencies and specificities in monkey kidney cells

1988 • 230 citations

DNA mismatch-repair in Escherichia coli counteracting the hydrolytic deamination of 5-methyl-cytosine residues.

1987 • 224 citations

p53 mutations in basal cell carcinomas.

1992 • 212 citations

A specific mismatch repair event protects mammalian cells from loss of 5-methylcytosine

1987 • 201 citations

Analysis of CpG suppression in methylated and nonmethylated species.

1992 • 135 citations

Heat- and alkali-induced deamination of 5-methylcytosine and cytosine residues in DNA

1982 • 130 citations

Spontaneous deamination of cytosine and 5-methylcytosine residues in DNA and replacement of 5-methylcytosine residues with cytosine residues

1990 • 123 citations

Bacterial genes mutL, mutS, and dcm participate in repair of mismatches at 5-methylcytosine sites

1987 • 117 citations

Preferential repair of DNA damage on the transcribed strand of the human metallothionein genes requires RNA polymerase II

1991 • 108 citations

Stranded in an active gene

1993 • 105 citations

The incidence and distribution of CpG←Tpg transitions in the coagulation factor IX gene. A fresh look at CPG mutitional hospots

1990 • 77 citations

Accuracy of DNA polymerase-alpha in copying natural DNA.

1983 • 56 citations

Asymmetric cytosine deamination revealed by spontaneous mutational specificity in an Ung− strain of Escherichia coli

1987 • 54 citations

Strand specificity for mutations induced by (+)-anti BPDE in the hprt gene in human T-lymphocytes

1992 • 48 citations

Transcription-dependent and independent DNA excision repair pathways in human cells

1992 • 42 citations

Recurrent nonsense mutations at arginine residues cause severe hemophilia B in unrelated hemophiliacs

1990 • 36 citations

Differential enhancement of spontaneous transition mutations in the lacI gene of an Ung− strain of Escherichia coli

1986 • 22 citations

Linked Spontaneous CG→TA Mutations at CpG Sites in the Gene for Protein Kinase Regulatory Subunit

1992 • 20 citations

Linked spontaneous CG----TA mutations at CpG sites in the gene for protein kinase regulatory subunit.

1992 • 12 citations