Studies on the miscoding properties of 1,N⁶-ethenoadenine and 3,N⁴-ethenocytosine, DNA reaction products of vinyl chloride metabolites, during in vitro DNA synthesis

Molecular Structure of Nucleic Acids: A Structure for Deoxyribose Nucleic Acid

1953 • 12,496 citations

Complementary base pairing and the origin of substitution mutations

1976 • 835 citations

Angiosarcoma of liver in the manufacture of polyvinyl chloride.

1974 • 538 citations

Formation and Metabolism of Alkylated Nucleosides: Possible Role in Carcinogenesis by Nitroso Compounds and Alkylating Agents

1977 • 304 citations

Fluorescent adenosine and cytidine derivatives

1972 • 283 citations

The properties of in templates for RNA polymerase

1973 • 264 citations

DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by

1979 • 247 citations

Mutagenic and alkylating metabolites of halo-ethylenes, chlorobutadienes and dichlorobutenes produced by rodent or human liver tissues

1979 • 221 citations

Mutagenicity of chloroacetaldehyde, a possible metabolic product of 1,2-dichloroethane (ethylene dichloride), chloroethanol (ethylene chlorohydrin), vinyl chloride, and cyclophosphamide.

1975 • 190 citations

Mutagenicity of vinyl chloride, chloroethyleneoxide, chloroacetaldehyde and chloroethanol

1975 • 177 citations

Liver-microsome-mediated formation of alkylating agents from vinyl bromide and vinyl chloride

1975 • 175 citations

The mutagenicity of chloroethylene oxide, chloroacetaldehyde, 2-chloroethanol and chloroacetic acid, conceivable metabolites of vinyl chloride

1976 • 160 citations

Carcinogenicity of Halogenated Olefinic and Aliphatic Hydrocarbons in Mice<xref ref-type="fn" rid="FN2">2</xref>

1979 • 142 citations

Chemical reactivity, metabolic oxirane formation and biological reactivity of chlorinated ethylenes in the isolated perfused rat liver preparation

1975 • 128 citations

Mutagenic and carcinogenic effects of vinyl chloride

1975 • 120 citations

A Fluorescent Analog of Nicotinamide Adenine Dinucleotide

1972 • 115 citations

Interactions of vinyl chloride with rat-liver DNA in vivo

1978 • 110 citations

DNA synthesis with methylated poly(dA-dT) templates: possible role of O⁴-methylthymine as a pro-mutagenic base

1977 • 88 citations

Carcinogenicity of chloroethylene oxide, an ultimate reactive metabolite of vinyl chloride, and bis(chloromethyl)ether after subcutaneous administration and in initiation-promotion experiments in mice.

1980 • 86 citations

Chloroacetaldehyde-modified dinucleoside phosphates. Dynamic fluorescence quenching and quenching due to intramolecular complexation

1974 • 85 citations

Mutation induction in chinese hamster V79 cells by two vinyl chloride metabolites, chloroethylene oxide and 2‐chloroacetaldehyde

1975 • 84 citations

Alkylation of RNA by vinyl chloride metabolites in vitro and in vivo: Formation of 1-N6-etheno-adenosine

1977 • 78 citations

Effects of depurination on the fidelity of DNA synthesis

1979 • 76 citations

Fluorescent Modification of Adenosine 3′,5′-Monophosphate: Spectroscopic Properties and Activity in Enzyme Systems

1972 • 76 citations

Mutagenicity of halogenated aliphatic hydrocarbons in Salmonella typhimurium, Streptomyces coelicolor and Aspergillus nidulans

1980 • 70 citations

Preparation and template activities of polynucleotides containing O2- and O4-alkyluridine.

1978 • 61 citations

Reaction of 1,3-bis(2-chloroethyl)-1-nitrosourea with synthetic polynucleotides

1975 • 59 citations

On the fidelity of DNA replication. Accuracy of Escherichia coli DNA polymerase I.

1979 • 57 citations

The reaction of guanosine and deoxyguanosine with glycidaldehyde

1968 • 57 citations

FLUORESCENT NUCLEOSIDES AND NUCLEOTIDES^*

1975 • 52 citations

Carcinogenicity of Halo-Ethers. II. Structure-Activity Relationships of Analogs of Bis(chloromethyl)ether<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref><xref ref-type="fn" rid="FN4">4</xref>

1972 • 49 citations

Formation of 3,N4-ethenocytidine moieties in RNA by vinyl chloride metabolites in vitro and in vivo

1978 • 48 citations

New observations concerning the chloroacetaldehyde reaction with some tRNA constituents. Stable intermediates, kinetics and selectivity of the reaction

1978 • 46 citations

Interaction of tobacco mosaic virus protein with synthetic polynucleotides containing a fluorescent label: optical properties of poly (A,εA) and poly (C,εC) copolymers and energy migration from the tryptophan to 1,N⁶or 3,N⁴-ethenocytosine residues in RNP

1978 • 46 citations

Induction of gene mutations and gene conversions by vinyl chloride metabolites in yeast.

1977 • 39 citations

Comment on the mutagenic effectiveness of vinyl chloride metabolites

1976 • 37 citations

Erroneous base-pairing induced by a chemical carcinogen during DNA synthesis

1974 • 36 citations

Alkylation of RNA by vinyl bromide metabolites in vitro and in vivo

1979 • 27 citations

Mechanism of action of the nitrosoureas—III

1979 • 26 citations

A Correlation between the Secondary Structure of DNA and the Reactivity of Adenine Residues with Chloroacetaldehyde

1977 • 25 citations

Physical studies of chloroacetaldehyde labelled fluorescent DNA

1973 • 24 citations

Synthesis and properties of a new fluorescent polynucleotide,

1973 • 21 citations

Enzymic activity and .gamma.-phosphorus-32 labeling of fluorescent derivatives of cytidine triphosphate and adenosine triphosphate

1973 • 21 citations

Polynucleotides. XIV. Synthesis and properties of polynucleotides containing 2,6-bis(methylthio)purine ribonucleotides

1972 • 9 citations

Polynucleotides XV. Synthesis and properties of polynucleotides containing N- acid residues in polyinosinate and polyadenylate chains

1972 • 7 citations

Synthesis and properties of poly (1,N-6-ethenoadenylic acid) and poly (3,N-4-ethenocytidylic acid).

1973 • 5 citations