H-2 K ^d -Restricted Hepatitis B Virus-Derived Epitope Whose Specific CD8 ⁺ T Lymphocytes Can Produce Gamma Interferon without Cytotoxicity

SYFPEITHI: database for MHC ligands and peptide motifs

1999 • 2,307 citations

Lineage relationship and protective immunity of memory CD8 T cell subsets

2003 • 1,833 citations

Hepatitis B Virus Immunopathogenesis

1995 • 1,568 citations

Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains.

1994 • 1,400 citations

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

1999 • 1,208 citations

Determinants of Viral Clearance and Persistence during Acute Hepatitis C Virus Infection

2001 • 1,183 citations

Intracellular Inactivation of the Hepatitis B Virus by Cytotoxic T Lymphocytes

1996 • 1,085 citations

Lymphocyte-Mediated Cytotoxicity

2002 • 1,079 citations

Noncytolytic Control of Viral Infections by the Innate and Adaptive ImmuneResponse

2001 • 1,000 citations

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

2002 • 986 citations

CD8⁺T Cells Mediate Viral Clearance and Disease Pathogenesis during Acute Hepatitis B Virus Infection

2002 • 913 citations

Cytotoxic T lymphocytes: all roads lead to death

2002 • 893 citations

The Role of Virus-Specific Cd8+ Cells in Liver Damage and Viral Control during Persistent Hepatitis B Virus Infection

2000 • 792 citations

CD8+ T Cell Effector Mechanisms in Resistance to Infection

2000 • 725 citations

A DNA vaccine induces SARS coronavirus neutralization and protective immunity in mice

2004 • 684 citations

Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease

2002 • 636 citations

High-level hepatitis B virus replication in transgenic mice

1995 • 625 citations

Large clonal expansions of CD8+ T cells in acute infectious mononucleosis

1996 • 478 citations

Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis.

1993 • 454 citations

CD8 T Cell Responses to Infectious Pathogens

2003 • 433 citations

Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection

2002 • 368 citations

Epitope-based vaccines: an update on epitope identification, vaccine design and delivery

2003 • 305 citations

Viruses, Immunity, and Cancer: Lessons from Hepatitis B

2000 • 294 citations

Immunopathogenesis and immunotherapy in AIDS virus infections

2003 • 235 citations

Prospects for Vaccine Protection Against HIV-1 Infection and AIDS

2002 • 184 citations

Immunization with hepatitis C virus-like particles protects mice from recombinant hepatitis C virus-vaccinia infection

2003 • 173 citations

Utilization of MHC Class I Transgenic Mice for Development of Minigene DNA Vaccines Encoding Multiple HLA-Restricted CTL Epitopes

1999 • 166 citations

High-Throughput Quantitative Analysis of Hepatitis B Virus DNA in Serum Using the TaqMan Fluorogenic Detection System

2000 • 163 citations

Immunogenicity and Tolerogenicity of Hepatitis B Virus Structural and Nonstructural Proteins: Implications for Immunotherapy of Persistent Viral Infections

2002 • 127 citations

Combining computer algorithms with experimental approaches permits the rapid and accurate identification of T cell epitopes from defined antigens

2001 • 97 citations

Impacts of Avidity and Specificity on the Antiviral Efficiency of HIV-1-Specific CTL

2003 • 96 citations

Real‐time PCR for detection and quantitation of hepatitis B virus DNA

2001 • 94 citations

Identification of an HLA-A*0201–restricted CD8+ T-cell epitope SSp-1 of SARS-CoV spike protein

2004 • 91 citations

Lack of Tumor Necrosis Factor Alpha Induces Impaired Proliferation of Hepatitis B Virus-Specific Cytotoxic T Lymphocytes

2003 • 90 citations

Epitope affinity for MHC class I determines helper requirement for CTL priming

2000 • 80 citations

DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb- and Kd-restricted epitopes

1997 • 77 citations

Overcoming T Cell Tolerance to the Hepatitis B Virus Surface Antigen in Hepatitis B Virus-Transgenic Mice

2001 • 74 citations

CD8+ T-cell interaction with HCV replicon cells: Evidence for both cytokine- and cell-mediated antiviral activity

2003 • 51 citations

A simple method to reduce the background and improve well-to-well reproducibility of staining in ELISPOT assays

2001 • 39 citations

Identification of HLA-A*0201-restricted cytotoxic T lymphocyte epitope from TRAG-3 antigen.

2003 • 33 citations

Adjuvants that enhance priming of cytotoxic T cells to a Kb-restricted epitope processed from exogenous but not endogenous hepatitis B surface antigen

1999 • 23 citations

High Peptide Affinity for MHC Class I does not Correlate with Immunodominance

1999 • 21 citations

Frequencies of epitope-specific cytotoxic T lymphocytes in active chronic viral hepatitis B infection by using MHC class I peptide tetramers

2004 • 21 citations

Quantitative and functional differences in CD8⁺ lymphocyte responses in resolved acute and chronic hepatitis C virus infection

2002 • 19 citations

A multidonor ELISPOT study of IL-1β, IL-2, IL-4, IL-6, IL-13, IFN-γ and TNF-α release by cryopreserved human peripheral blood mononuclear cells

2002 • 17 citations

Immunogenicity of H-2Kb-low affinity, high affinity, and covalently-bound peptides in anti-tumor vaccination

1999 • 16 citations

Alloreactive Cytotoxic T‐Cell Function, Peptide Nonspecific

1999 • 15 citations

Effective elicitation of anti-tumor immunity by collocation of antigen with encoding gene in the same vaccine

2003 • 8 citations

Hepatitis B virus transgenic mice for the model of anti-hepatitis B virus drug study.

2001 • 5 citations