CD8+ T-cell interaction with HCV replicon cells: Evidence for both cytokine- and cell-mediated antiviral activity

Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line

1999 • 2,796 citations

INTERFERONS AND THEIR ACTIONS

1987 • 1,838 citations

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

2002 • 1,583 citations

Fas and Perforin Pathways as Major Mechanisms of T Cell-Mediated Cytotoxicity

1994 • 1,558 citations

Efficient Initiation of HCV RNA Replication in Cell Culture

2000 • 1,412 citations

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

1999 • 1,208 citations

Intracellular Inactivation of the Hepatitis B Virus by Cytotoxic T Lymphocytes

1996 • 1,085 citations

Effect of Alpha Interferon on the Hepatitis C Virus Replicon

2001 • 450 citations

A natural killer cell granule protein that induces DNA fragmentation and apoptosis.

1992 • 379 citations

Immunohistochemical detection of Fas antigen in liver tissue of patients with chronic hepatitis C

1994 • 363 citations

Interferon-γ inhibits replication of subgenomic and genomic hepatitis C virus RNAs

2002 • 315 citations

Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV

1993 • 290 citations

Apoptosis and hepatobiliary disease

1995 • 268 citations

Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients

1996 • 265 citations

Comprehensive Analysis of CD8⁺-T-Cell Responses against Hepatitis C Virus Reveals Multiple Unpredicted Specificities

2002 • 188 citations

Dynamics of intra-hepatic lymphocytes in chronic hepatitis C: enrichment for Vα24+ T cells and rapid elimination of effector cells by apoptosis

1998 • 166 citations

Noncytopathic Clearance of Lymphocytic Choriomeningitis Virus from the Hepatocyte

1999 • 146 citations

Colon carcinoma cells use different mechanisms to escape CD95-mediated apoptosis.

1998 • 140 citations

Hepatitis B Virus Transgenic Mice: Models of Viral Immunobiology and Pathogenesis

1996 • 134 citations

The HCV Core Protein Acts as a Positive Regulator of Fas-Mediated Apoptosis in a Human Lymphoblastoid T Cell Line

2000 • 123 citations

Protection or damage: a dual role for the virus-specific cytotoxic T lymphocyte response in hepatitis B and C infection?

2000 • 120 citations

Cytochrome P450-generated reactive metabolites cause mitochondrial permeability transition, caspase activation, and apoptosis in rat hepatocytes

2000 • 109 citations

Gene expression associated with interferon alfa antiviral activity in an HCV replicon cell line

2003 • 106 citations

THE IMMUNOPATHOGENESIS OF HEPATITIS C VIRUS INFECTION

2001 • 72 citations