Determinants of Viral Clearance and Persistence during Acute Hepatitis C Virus Infection

HLA‐DR typing by PCR amplification with sequence‐specific primers (PCR‐SSP) in 2 hours: An alternative to serological DR typing in clinical practice including donor‐recipient matching in cadaveric transplantation

1992 • 1,846 citations

The Natural History of Community-Acquired Hepatitis C in the United States

1992 • 1,614 citations

Analysis of Successful Immune Responses in Persons Infected with Hepatitis C Virus

2000 • 1,270 citations

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

1999 • 1,208 citations

Intracellular Inactivation of the Hepatitis B Virus by Cytotoxic T Lymphocytes

1996 • 1,085 citations

Analysis of a Successful Immune Response against Hepatitis C Virus

1999 • 823 citations

Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C

2000 • 747 citations

Recurrence of hepatitis C virus after loss of virus-specific CD4+ T-cell response in acute hepatitis C

1999 • 716 citations

Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection

1995 • 702 citations

Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response.

1996 • 669 citations

Sustained Dysfunction of Antiviral CD8⁺T Lymphocytes after Infection with Hepatitis C Virus

2001 • 496 citations

Intrahepatic cytotoxic T lymphocytes specific for hepatitis C virus in persons with chronic hepatitis.

1992 • 465 citations

Quantitative analysis of hepatitis C virus-specific CD8⁺T cells in peripheral blood and liver using peptide-MHC tetramers

1999 • 421 citations

Pathogenesis of chronic hepatitis C: Immunological features of hepatic injury and viral persistence

1999 • 419 citations

Detection of type 2-like T-helper cells in hepatitis C virus infection: Implications for hepatitis C virus chronicity

1997 • 413 citations

Cytotoxic T cells and viral hepatitis.

1997 • 372 citations

Association of Hepatitis C Virus–Specific CD8⁺T Cells with Viral Clearance in Acute Hepatitis C

2000 • 362 citations

Differential CD4+ and CD8+ T-cell responsiveness in hepatitis C virus infection

2001 • 345 citations

Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant.

1995 • 344 citations

Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus.

1997 • 333 citations

HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release.

1995 • 329 citations

Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA A2.1 binding motif.

1995 • 322 citations

T-lymphocyte response to hepatitis C virus in different clinical courses of infection

1993 • 317 citations

The role of hepatitis C virus-specific cytotoxic T lymphocytes in chronic hepatitis C.

1997 • 316 citations

CD8+ T lymphocyte responses are induced during acute hepatitis C virus infection but are not sustained

2000 • 313 citations

Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection.

1996 • 294 citations

Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV

1993 • 290 citations

Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients

1996 • 265 citations

T-cell response to structural and nonstructural hepatitis C virus antigens in persistent and self-limited hepatitis C virus infections

1994 • 239 citations

Patients with chronic hepatitis C have circulating cytotoxic T cells which recognize hepatitis C virus-encoded peptides binding to HLA-A2.1 molecules

1995 • 216 citations

Acute hepatitis C

2001 • 193 citations

Mapping of immunodominant CD4+ T lymphocyte epitopes of hepatitis C virus antigens and their relevance during the course of chronic infection

1995 • 149 citations

Cell Mediated Immune Response to the Hepatitis C Virus

2000 • 126 citations

Hepatitis C virus (HCV) specific immune responses in anti-HCV positive patients without hepatitis C viraemia

1999 • 115 citations

Immunopathology of hepatitis C

1997 • 79 citations

High levels of viral replication during acute hepatitis B infection predict progression to chronicity

1994 • 68 citations

Assessment of Hepatitis C Virus Sequence Complexity by Electrophoretic Mobilities of Both Single-and Double-Stranded DNAs

1998 • 39 citations