Back to search

A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia

Data up to Jan 2025

Published2003
Citations656
References42

Total Citations Per Year

Abstract

References (42)

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Tissue Plasminogen Activator for Acute Ischemic Stroke

1995 • 10,997 citations

Pathobiology of ischaemic stroke: an integrated view

1999 • 3,776 citations

A central role for JNK in obesity and insulin resistance

2002 • 3,225 citations

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

2001 • 2,488 citations

In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse

1999 • 2,410 citations

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1997 • 2,291 citations

Effects of Cerebral Ischemia in Mice Deficient in Neuronal Nitric Oxide Synthase

1994 • 1,578 citations

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1997 • 1,229 citations

Activation and Cleavage of Caspase-3 in Apoptosis Induced by Experimental Cerebral Ischemia

1998 • 899 citations

The Jnk1 and Jnk2 Protein Kinases Are Required for Regional Specific Apoptosis during Early Brain Development

1999 • 888 citations

Inhibition of interleukin 1β converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

1997 • 835 citations

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

1999 • 676 citations

The Yin and Yang of NMDA receptor signalling

2003 • 627 citations

Toward Wisdom From Failure

2002 • 619 citations

The new enzymology of precursor processing endoproteases.

1992 • 608 citations

Cell-Permeable Peptide Inhibitors of JNK

2001 • 581 citations

Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.

1995 • 535 citations

Cerebral ischemia and inflammation

2001 • 459 citations

Activation and redistribution of c‐Jun N‐terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease

2001 • 412 citations

Treatment of Acute Ischemic Stroke

2000 • 391 citations

Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage

1995 • 378 citations

Neuronal Apoptosis After CNS Injury: The Roles of Glutamate and Calcium

2000 • 290 citations

Prolonged Therapeutic Window for Ischemic Brain Damage Caused by Delayed Caspase Activation

1998 • 219 citations

Identification of the Critical Features of a Small Peptide Inhibitor of JNK Activity

2002 • 210 citations

Glutamate‐Mediated Injury in Focal Cerebral Ischemia: The Excitotoxin Hypothesis Revised

1994 • 199 citations

Dual Roles for c-Jun N-Terminal Kinase in Developmental and Stress Responses in Cerebellar Granule Neurons

2000 • 192 citations

Sending signals from the synapse to the nucleus: Possible roles for CaMK, Ras/ERK, and SAPK pathways in the regulation of synaptic plasticity and neuronal growth

1999 • 133 citations

Activation of Mitogen-Activated Protein Kinases After Permanent Cerebral Artery Occlusion in Mouse Brain

2000 • 121 citations

Kainate Receptor Activation Induces Mixed Lineage Kinase-mediated Cellular Signaling Cascades via Post-synaptic Density Protein 95

2001 • 110 citations

Ca2+‐Mediated Activation of c‐Jun N‐Terminal Kinase and Nuclear Factor κB by NMDA in Cortical Cell Cultures

1998 • 101 citations

The Retro-inverso Form of a Homeobox-Derived Short Peptide Is Rapidly Internalized by Cultured Neurons: A New Basis for an Efficient Intracellular Delivery System

1995 • 101 citations

Carboxyl‐terminal fragment of Alzheimer's APP destabilizes calcium homeostasis and renders neuronal cells vulnerable to excitotoxicity

2000 • 90 citations

Seizure-induced neuronal death is associated with induction of c-Jun N-terminal kinase and is dependent on genetic background

2000 • 74 citations

NMDA Receptor Blockade Fails to Alter Axonal Injury in Focal Cerebral Ischemia

2000 • 71 citations

A comparative assessment of the efficacy and side-effect liability of neuroprotective compounds in experimental stroke

2001 • 69 citations

Extension of the Therapeutic Window for Recombinant Tissue Plasminogen Activator With Argatroban in a Rat Model of Embolic Stroke

2001 • 68 citations

White matter ischaemia

1999 • 63 citations

Synergistic protective effect of caspase inhibitors and bFGF against brain injury induced by transient focal ischaemia

2001 • 56 citations

Preservation of cholinergic activity and prevention of neuron death by CEP-1347/KT-7515 following excitotoxic injury of the nucleus basalis magnocellularis

1998 • 39 citations

New Method for the Quantitative Assessment of Axonal Damage in Focal Cerebral Ischemia

2002 • 29 citations

Cited By (0)

No citing papers found in database

A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and… (2003) – Nature Medicine | Metascience Observatory Explorer