Mechanism of PDX-1 protein transduction

Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen

2000 • 5,125 citations

In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse

1999 • 2,410 citations

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1997 • 2,291 citations

Insulin-promoter-factor 1 is required for pancreas development in mice

1994 • 1,789 citations

Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells.

1988 • 1,737 citations

Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis

2004 • 1,606 citations

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

1996 • 1,505 citations

Cell-penetrating Peptides

2002 • 1,392 citations

Cell Internalization of the Third Helix of the Antennapedia Homeodomain Is Receptor-independent

1996 • 1,047 citations

In vitro cultivation of human islets from expanded ductal tissue

2000 • 972 citations

Intercellular Trafficking and Protein Delivery by a Herpesvirus Structural Protein

1997 • 962 citations

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

2000 • 741 citations

Trojan peptides: the penetratin system for intracellular delivery

1998 • 707 citations

Studies on the Internalization Mechanism of Cationic Cell-penetrating Peptides

2003 • 528 citations

IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene.

1994 • 427 citations

Transplantation of Cultured Islets from Two-Layer Preserved Pancreases in Type 1 Diabetes with Anti-CD3 Antibody

2004 • 367 citations

Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells.

1993 • 332 citations

Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor.

1996 • 328 citations

A Stepwise Dissection of the Intracellular Fate of Cationic Cell-penetrating Peptides

2004 • 280 citations

Messenger proteins: homeoproteins, TAT and others

2000 • 274 citations

A new cell-permeable peptide allows successful allogeneic islet transplantation in mice

2004 • 272 citations

NEW EMBO MEMBERS' REVIEW: Entry of ricin and Shiga toxin into cells: molecular mechanisms and medical perspectives

2000 • 249 citations

Positively Charged DNA-Binding Proteins Cause Apparent Cell Membrane Translocation

2002 • 231 citations

PDX-1 Protein Containing Its Own Antennapedia-Like Protein Transduction Domain Can Transduce Pancreatic Duct and Islet Cells

2003 • 215 citations

Cell-Dependent Differential Cellular Uptake of PNA, Peptides, and PNA-Peptide Conjugates

2002 • 214 citations

Lilly Lecture 2002

2003 • 206 citations

Toxin Entry: Retrograde Transport through the Secretory Pathway

1998 • 186 citations

Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells

1993 • 183 citations

Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor

1996 • 180 citations

Nuclear Targeting of Macromolecular Polyanions by an HIV-Tat Derived Peptide

2002 • 173 citations

A High-Efficiency Protein Transduction System Demonstrating the Role of PKA in Long-Lasting Long-Term Potentiation

2001 • 170 citations

Can transcription factors function as cell–cell signalling molecules?

2003 • 161 citations

Identification of a signal sequence necessary for the unconventional secretion of Engrailed homeoprotein

1998 • 158 citations

The Insulin Gene Contains Multiple Transcriptional Elements That Respond to Glucose

1994 • 145 citations

Glucose-Induced Transcription of the Insulin Gene Is Mediated by Factors Required for β-Cell-Type-Specific Expression

1994 • 118 citations

A short region of its homeodomain is necessary for Engrailed nuclear export and secretion

1999 • 107 citations

Association of Engrailed homeoproteins with vesicles presenting caveolae-like properties

1997 • 100 citations

Engrailed homeoprotein secretion is a regulated process

2002 • 98 citations

Protein Therapy: In Vivo Protein Transduction by Polyarginine (11R) PTD and Subcellular Targeting Delivery

2003 • 73 citations

Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression.

1994 • 67 citations

PDX-1 Protein is Internalized by Lipid Raft-Dependent Macropinocytosis

2005 • 47 citations

LRetrograde trafficking of both Golgi complex and TGN markers to the ER induced by nordihydroguaiaretic acid and cyclofenil diphenol

1998 • 39 citations

DELIVERY OF PROTEINS AND PEPTIDES INTO LIVE CELLS BY MEANS OF PROTEIN TRANSDUCTION DOMAINS: POTENTIAL APPLICATION TO ORGAN AND CELL TRANSPLANTATION

2004 • 18 citations