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Mutational hot spots in Ig V region genes of human follicular lymphomas.

Data up to Jan 2025

Published1988
Citations86
References38

Total Citations Per Year

Abstract

References (38)

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ

1977 • 4,696 citations

Sequences of proteins of immunological interest

1984 • 3,427 citations

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

Derivation of specific antibody‐producing tissue culture and tumor lines by cell fusion

1976 • 1,926 citations

Lambda replacement vectors carrying polylinker sequences

1983 • 1,809 citations

Molecular basis of base substitution hotspots in Escherichia coli

1978 • 1,185 citations

Mutation Drift and Repertoire Shift in the Maturation of the Immune Response

1987 • 635 citations

Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin.

1984 • 545 citations

Patterns of nucleotide substitution in pseudogenes and functional genes

1982 • 460 citations

Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments

1980 • 402 citations

Evolutionary and Somatic Selection of the Antibody Repertoire in the Mouse

1987 • 388 citations

Clustered arrangement of immunoglobulin λ constant region genes in man

1981 • 379 citations

Nonrandomness of point mutation as reflected in nucleotide substitutions in pseudogenes and its evolutionary implications

1984 • 369 citations

Differentiation-Linked Leukemogenesis in Lymphocytes

1986 • 359 citations

Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin.

1985 • 319 citations

Evolution of human immunoglobulin kappa J region genes.

1982 • 318 citations

Clustering of extensive somatic mutations in the variable region of an immunoglobulin heavy chain gene from a human B cell lymphoma

1986 • 279 citations

Emergence of Idiotype Variants during Treatment of B-Cell Lymphoma with Anti-Idiotype Antibodies

1985 • 257 citations

Analysis of somatic mutation and class switching in naive and memory B cells generating adoptive primary and secondary responses

1987 • 230 citations

Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP.

1986 • 227 citations

Role of chromosome translocations in human neoplasia

1987 • 226 citations

Somatic evolution of variable region structures during an immune response.

1986 • 211 citations

Mouse × human heterohybridomas as fusion partners with human B cell tumors

1986 • 171 citations

Patterns of Somatic Mutations in Immunoglobulin Variable Genes

1987 • 158 citations

Rescue of immunoglobulin secretion from human neoplastic lymphoid cells by somatic cell hybridization.

1978 • 131 citations

Somatic evolution of diversity among anti-phosphocholine antibodies induced with Proteus morganii.

1987 • 87 citations

Somatic Mutation in Anti‐Phosphorylcholine Antibodies

1987 • 82 citations

Human ? light chain locus: Organization and DNA sequences of three genomicJ regions

1987 • 77 citations

Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin.

1986 • 69 citations

Idiotype variant cell populations in patients with B cell lymphoma.

1986 • 52 citations

Immunoglobulin secretion by mouse X human hybridomas: an approach for the production of anti-idiotype reagents useful in monitoring patients with B cell lymphoma.

1980 • 49 citations

A rapid method for cloning and sequencing variable-region genes of expressed immunoglobulins

1987 • 38 citations

Retention of an idiotypic determinant in a human B-cell lymphoma undergoing immunoglobulin variable-region mutation.

1987 • 25 citations

Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP

1989 • 1 citations

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Mutational hot spots in Ig V region genes of human follicular lymphomas. (1988) – The Journal of Experimental Medicine | Metascience Observatory Explorer