Induction of p21 mRNA Synthesis After Short-wavelength UV Light Visualized in Individual Cells by RNA FISH

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

Requirement for p53 and p21 to Sustain G ₂ Arrest After DNA Damage

1998 • 2,784 citations

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

1994 • 2,025 citations

Differential induction of transcriptionally active p53 following UV or lonizing radiation: Defects in chromosome instability syndromes?

1993 • 799 citations

HuR Regulates p21 mRNA Stabilization by UV Light

2000 • 534 citations

Resistance to Apoptosis Conferred by Cdk Inhibitors During Myocyte Differentiation

1996 • 494 citations

Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21.

1994 • 363 citations

Inhibition of RNA polymerase II as a trigger for the p53 response

1999 • 287 citations

Nonrandom gene organization: structural arrangements of specific pre-mRNA transcription and splicing with SC-35 domains.

1995 • 251 citations

The cellular organization of gene expression

1998 • 243 citations

In vivo analysis of the stability and transport of nuclear poly(A)+ RNA.

1994 • 233 citations

The residual repair capacity of xeroderma pigmentosum complementation group C fibroblasts is highly specific for transcriptionally active DNA

1990 • 231 citations

In vivo gene therapy with p53 or p21 adenovirus for prostate cancer.

1995 • 227 citations

Inefficient processing impairs release of RNA from the site of transcription

1999 • 227 citations

The Cyclin-Dependent Kinase Inhibitor p21^WAF1 Is Required for Survival of Differentiating Neuroblastoma Cells

1996 • 226 citations

Processing of Endogenous Pre-mRNAs in Association with SC-35 Domains Is Gene Specific

1999 • 194 citations

Protective Role of p21^Waf1/Cip1 against Prostaglandin A₂-Mediated Apoptosis of Human Colorectal Carcinoma Cells

1996 • 160 citations

Localization of pre-messenger RNA at discrete nuclear sites.

1991 • 131 citations

p21 (WAF1/CIP1) Expression Is Induced in Newly Nondividing Cells in Diverse Epithelia and during Differentiation of the Caco-2 Intestinal Cell Line

1996 • 119 citations

Nuclear pre-mRNA Compartmentalization: Trafficking of Released Transcripts to Splicing Factor Reservoirs

2000 • 108 citations

Aberrant p21CIP1/WAF1 protein accumulation in head-and-neck cancer

1997 • 106 citations

p53-Dependent Elevation of p21^Waf1 Expression by UV Light Is Mediated through mRNA Stabilization and Involves a Vanadate-Sensitive Regulatory System

1998 • 106 citations

Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis

1998 • 94 citations

5′-terminal caps of snRNAs are reactive with antibodies specific for 2,2,7-trimethylguanosine in whole cells and nuclear matrices

1984 • 79 citations

Effects of a recombinant adenovirus expressing WAF1/Cip1 on cell growth, cell cycle, and apoptosis.

1995 • 77 citations

Methodologies for specific intron and exon RNA localization in cultured cells by haptenized and fluorochromized probes

1993 • 68 citations

A p53-independent pathway for induction of p21waf1cip1 and concomitant G1 arrest in UV-irradiated human skin fibroblasts.

1997 • 63 citations

Nuclear RNA tracks: structural basis for transcription and splicing?

1993 • 57 citations

CCD microscopy and image analysis of cells and chromosomes stained by fluorescence in situ hybridization

1995 • 52 citations

Splicing factors associate with nuclear HCMV-IE transcripts after transcriptional activation of the gene, but dissociate upon transcription inhibition: evidence for a dynamic organization of splicing factors

1997 • 45 citations

Ultraviolet radiation down-regulates expression of the cell-cycle inhibitor p21WAF1/CIP1 in human cancer cells independently of p53

1999 • 42 citations

Demonstration of a dynamic, transcription-dependent organization of pre-mRNA splicing factors in polytene nuclei.

1996 • 40 citations

Synthesis, Processing, and Transport of RNA within the Three-Dimensional Context of the Cell Nucleus

1999 • 29 citations

GM1492 Human Diploid Skin Fibroblasts Lack the p53-Dependent G1 Cell-Cycle Checkpoint

1995 • 13 citations