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Aberrant p21CIP1/WAF1 protein accumulation in head-and-neck cancer

Data up to Jan 2025

Published1997
Citations106
References21

Total Citations Per Year

Abstract

References (21)

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

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p21 is a universal inhibitor of cyclin kinases

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Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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1995 • 1,058 citations

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1993 • 778 citations

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1995 • 593 citations

Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/CIP1, expression in the absence of p53.

1994 • 514 citations

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1994 • 493 citations

Absence of WAF1 mutations in a variety of human malignancies

1994 • 390 citations

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1994 • 231 citations

Increased levels of p21WAF1/Cip1 in human brain tumors.

1995 • 159 citations

p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma.

1995 • 134 citations

Genetic change in actinic keratoses.

1996 • 95 citations

Expression of p21WAF1/CIP1 is heterogeneous and unrelated to proliferation index in human ovarian carcinoma

1995 • 58 citations

Expression of the histone H3 gene in benign, semi-malignant and malignant lesions of the head and neck: a reliable proliferation marker

1993 • 47 citations

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