Iris Pigment Epithelium Expressing CD86 (B7-2) Directly Suppresses T Cell Activation In Vitro via Binding to Cytotoxic T Lymphocyte–associated Antigen 4

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

Cytotoxic T Lymphocyte–Associated Antigen 4 Plays an Essential Role in the Function of Cd25+Cd4+ Regulatory Cells That Control Intestinal Inflammation

2000 • 2,211 citations

Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4

2000 • 2,207 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

The B7 and CD28 receptor families

1994 • 1,342 citations

A role for CD95 ligand in preventing graft rejection

1995 • 1,184 citations

The B7 Family of Ligands and Its Receptors: New Pathways for Costimulation and Inhibition of Immune Responses

2002 • 884 citations

New perspectives of C1328-137-mediated T cell costimulation

1995 • 526 citations

Human CD25+CD4+ T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells

2002 • 440 citations

CTLA-4 Regulates Induction of Anergy In Vivo

2001 • 409 citations

Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?

1997 • 403 citations

Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments

1993 • 216 citations

Accessory Cell Signals Involved in T‐Cell Activation

1990 • 160 citations

Identification of transforming growth factor-beta expressed in cultured human retinal pigment epithelial cells.

1993 • 157 citations

Ocular Immunosuppressive Microenvironment

2007 • 143 citations

Immune deviation in relation to ocular immune privilege

1998 • 137 citations

Antigens for γ/δ T cells

1989 • 115 citations

Participation of pigment epithelium in ocular immune privilege. 3. Epithelia cultured from iris, ciliary body, and retina suppress T-cell activation by partially non-overlapping mechanisms

2003 • 113 citations

Fas-independent death of activated CD4⁺T lymphocytes induced by CTLA-4 crosslinking

1998 • 112 citations

Human retinal pigment epithelial cell-induced apoptosis in activated T cells.

1998 • 104 citations

Immune deviation in relation to ocular immune privilege.

1997 • 95 citations

Ocular immune privilege and the Faustian dilemma. The Proctor lecture.

1996 • 76 citations

Specific aqueous humor factors induce activation of regulatory T cells.

1999 • 76 citations

Analysis of immunosuppressive properties of iris and ciliary body cells and their secretory products.

1991 • 73 citations

Production of latent transforming growth factor-beta and other inhibitory factors by cultured murine iris and ciliary body cells

1991 • 68 citations

Participation of pigment epithelium of iris and ciliary body in ocular immune privilege. 1. Inhibition of T-cell activation in vitro by direct cell-to-cell contact.

2000 • 58 citations

Ocular Immunosuppressive Microenvironment

1999 • 51 citations

CD3⁺ WT31⁻ peripheral T lymphocytes lack T44 (CD28), a surface molecule involved in activation of T cells bearing the α/β heterodimer

1987 • 50 citations

Participation of pigment epithelium of iris and ciliary body in ocular immune privilege. 2. Generation of TGF-beta-producing regulatory T cells.

2000 • 42 citations

Increased transgene expression by the mouse tyrosinase enhancer is restricted to neural crest-derived pigment cells

2001 • 41 citations

Molecular basis of ACAID

1997 • 26 citations

RT in situ PCR for the detection of mRNA transcripts of Fas-L in the immune-privileged placental environment.

1998 • 7 citations