Increased transgene expression by the mouse tyrosinase enhancer is restricted to neural crest-derived pigment cells

Essential role for oncogenic Ras in tumour maintenance

1999 • 880 citations

Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage

2000 • 465 citations

Tyrosinase and related proteins in mammalian pigmentation

1996 • 439 citations

TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor

1992 • 409 citations

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

1997 • 405 citations

The temporal requirement for endothelin receptor-B signalling during neural crest development

1999 • 347 citations

Activation of the Receptor Tyrosine Kinase Kit Is Required for the Proliferation of Melanoblasts in the Mouse Embryo

1997 • 317 citations

Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway

1995 • 280 citations

A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice

1993 • 275 citations

The retinal pigmented epithelium is required for development and maintenance of the mouse neural retina

1995 • 217 citations

Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice

1990 • 209 citations

Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice.

1990 • 182 citations

High-Molecular-Weight Forms of Tyrosinase and the Tyrosinase-Related Proteins: Evidence for a Melanogenic Complex

1994 • 143 citations

A cell-specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number-related expression in transgenic mice.

1994 • 116 citations

The mouse tyrosinase promoter is sufficient for expression in melanocytes and in the pigmented epithelium of the retina.

1991 • 113 citations

Expression of the mouse tyrosinase gene during embryonic development: recapitulation of the temporal regulation in transgenic mice.

1992 • 107 citations

The Gene Encoding the T-box Factor Tbx2 Is a Target for the Microphthalmia-associated Transcription Factor in Melanocytes

2000 • 105 citations

New evidence for presence of tyrosinase in substantia nigra, forebrain and midbrain

1998 • 103 citations

The mouse tyrosinase gene. Promoter modulation by positive and negative regulatory elements.

1994 • 94 citations

A locus control region at −12 kb of the tyrosinase gene.

1996 • 85 citations

Receptor tyrosine kinase‐dependent neural crest migration in response to differentially localized growth factors

1997 • 79 citations

Cloning, sequence determination, and expression in transfected cells of the coding sequence for the tox 176 attenuated diphtheria toxin A chain.

1987 • 78 citations

Tyrosinase-Related Protein 2 Promoter Targets Transgene Expression to Ocular and Neural Crest-Derived Tissues

1999 • 71 citations

A distal tyrosinase upstream element stimulates gene expression in neural-crest-derived melanocytes of transgenic mice: position-independent and mosaic expression

1994 • 68 citations

Mosaicism of tyrosinase‐locus transcription and chromatin structure in dark vs. light melanocyte clones of homozygous chinchilla‐mottled mice

1991 • 64 citations

Endothelin signalling in the development of neural crest-derived melanocytes

1998 • 62 citations

Activation of a Diphtheria Toxin A Gene by Expression of Human Immunodeficiency Virus-1 Tat and Rev Proteins in Transfected Cells

1991 • 62 citations

Migration and proliferation of cultured neural crest cells in W mutant neural crest chimeras

1991 • 59 citations

Distal upstream tyrosinase S/MAR-containing sequence has regulatory properties specific to subsets of melanocytes

1999 • 44 citations

Tyrosinase is a new marker for cell populations in the mouse neural tube

1996 • 39 citations

lacZ Transgenic mice to monitor gene expression in embryo and adult

1998 • 31 citations

Survival of patchwork melanoblasts is dependent upon their number in the hair follicle at the end of embryogenesis

1998 • 29 citations

TheFugu rubripes tyrosinase gene promoter targets transgene expression to pigment cells in the mouse

2000 • 25 citations

Ectopic expression of ret results in microphthalmia and tumors in the retinal pigment epithelium

1999 • 24 citations

The use of yeast artificial chromosomes in transgenic animals: expression studies of the tyrosinase gene in transgenic mice

1999 • 21 citations

Analysis of the Mouse Tyrosinase Promoter In Vitro and In Vivo

1994 • 17 citations

[Cellular and molecular features of mammalian pigmentation--tyrosinase and TRP].

2000 • 13 citations

Strain‐Specific White‐Spotting Patterns in Laboratory Mice

1999 • 11 citations

Regulation of the Tyrosinase Promoter in Transgenic Mice: Expression of a TyrosinaselacZ Fusion Gene in Embryonic and Adult Brain

1997 • 11 citations

Nomenclature for Identified Pigmentation Genes in the Mouse

2000 • 10 citations