Participation of pigment epithelium of iris and ciliary body in ocular immune privilege. 1. Inhibition of T-cell activation in vitro by direct cell-to-cell contact.

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Apoptosis by Death Factor

1997 • 5,038 citations

Cellular and Molecular Immunology

1994 • 3,469 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye.

1948 • 1,042 citations

Differential regulation of T helper phenotype development by interleukins 4 and 10 in an alpha beta T-cell-receptor transgenic system.

1992 • 762 citations

Identification of transforming growth factor-beta as an immunosuppressive factor in aqueous humor.

1991 • 470 citations

CD95-Induced Apoptosis of Lymphocytes in an Immune Privileged Site Induces Immunological Tolerance

1996 • 394 citations

CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival.

1997 • 375 citations

Membrane proteins that protect against complement lysis

1994 • 270 citations

Aqueous humor contains transforming growth factor-beta and a small (less than 3500 daltons) inhibitor of thymocyte proliferation.

1990 • 234 citations

Identification of alpha-melanocyte stimulating hormone as a potential immunosuppressive factor in aqueous humor

1992 • 225 citations

Immune regulation and the eye: a dangerous compromise

1987 • 217 citations

Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments

1993 • 216 citations

Immunoreactive vasoactive intestinal peptide contributes to the immunosuppressive activity of normal aqueous humor.

1994 • 207 citations

Studies on the induction of anterior chamber-associated immune deviation (ACAID). 1. Evidence that an antigen-specific, ACAID-inducing, cell-associated signal exists in the peripheral blood.

1991 • 179 citations

Subretinal space and vitreous cavity as immunologically privileged sites for retinal allografts.

1993 • 178 citations

Identification of transforming growth factor-beta expressed in cultured human retinal pigment epithelial cells.

1993 • 157 citations

On the mechanisms by which transforming growth factor‐β2 alters antigen‐presenting abilities of macrophages on T cell activation

1997 • 121 citations

Organ-Resident, Nonlymphoid Cells Suppress Proliferation of Autoimmune T-Helper Lymphocytes

1987 • 118 citations

Suppression of nitric oxide generated by inflammatory macrophages by calcitonin gene-related peptide in aqueous humor.

1998 • 108 citations

Human retinal pigment epithelial cell-induced apoptosis in activated T cells.

1998 • 104 citations

Aqueous humor induces transforming growth factor-ß (TGF-ß)-producing regulatory T-cells

1997 • 102 citations

Inhibition of lymphocyte proliferation by aqueous humor.

1989 • 96 citations

Hapten-Specific Tolerance Induced by Acute, Low-Dose Ultraviolet B Radiation of Skin Is Mediated via Interleukin-10

1997 • 94 citations

Retinal Pigment Epithelial Cells Modulate Lymphocyte Function at the Blood-Retina Barrier by Autocrine PGE2 and Membrane-Bound Mechanisms

1993 • 92 citations

Macrophages capable of inducing anterior chamber associated immune deviation demonstrate spleen-seeking migratory properties.

1992 • 87 citations

Ocular immune privilege and the Faustian dilemma. The Proctor lecture.

1996 • 76 citations

Analysis of immunosuppressive properties of iris and ciliary body cells and their secretory products.

1991 • 73 citations

Production of latent transforming growth factor-beta and other inhibitory factors by cultured murine iris and ciliary body cells

1991 • 68 citations

Immunohistochemical localization of transforming growth factor-beta 1, -beta 2, and -beta 3 latency-associated peptide in human cornea.

1994 • 67 citations

Differential activation of antigen-stimulated suicide and cytokine production pathways in CD4+ T cells is regulated by the antigen-presenting cell.

1993 • 62 citations

Mammalian ciliary-body epithelial cells in culture produce transforming growth factor-beta

1991 • 55 citations

Dual effect of ciliary body cells on T lymphocyte proliferation

1990 • 50 citations

Expression and Secretion of Transforming Growth Factor-β in Transformed and Nontransformed Retinal Pigment Epithelial Cells

1994 • 41 citations

Inhibition of lymphocyte proliferation by resident ocular cells

1991 • 31 citations

Human fetal retinal pigment epithelial cells induce apoptosis in the T-cell line Jurkat.

1999 • 24 citations

Antigen processing and presentation in the eye: a review

1992 • 23 citations

Corneal endothelial cells block T cell proliferation, but not T cell activation or responsiveness to exogenous IL-2

1994 • 17 citations

Effect of intraocular gamma-interferon on immunoregulatory properties of iris and ciliary body cells.

1992 • 15 citations

Immunosuppressive properties of tissues of the ocular anterior segment

1996 • 12 citations