Expression and Purification of Human Stromelysin 1 and 3 from Baculovirus-Infected Insect Cells

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

A Manual of Methods for Baculovirus Vectors and Insect Cell Culture Procedures.

1987 • 1,703 citations

Tumor Cell Interactions with the Extracellular Matrix During Invasion and Metastasis

1993 • 1,523 citations

The matrix‐degrading metalloproteinases

1992 • 1,383 citations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1990 • 1,140 citations

Activation mechanisms of matrix metalloproteinases.

1997 • 1,134 citations

Proteolytic remodeling of extracellular matrix

1995 • 1,086 citations

Tissue Inhibitor of Metalloproteinase (TIMP-2)

1989 • 899 citations

α-Macroglobulins: structure, shape, and mechanism of proteinase complex formation

1989 • 673 citations

Furin-dependent intracellular activation of the human stromelysin-3 zymogen

1995 • 620 citations

Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.

1992 • 620 citations

Expression of most matrix metalloproteinase family members in breast cancer represents a tumor-induced host response.

1996 • 515 citations

A metalloproteinase from human rheumatoid synovial fibroblasts that digests connective tissue matrix components. Purification and characterization.

1986 • 515 citations

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.

1995 • 511 citations

Matrix metalloproteinase inhibitors

1997 • 509 citations

Contributions of tumor and stromal matrix metalloproteinases to tumor progression, invasion and metastasis

1995 • 429 citations

Increased stromelysin 3 gene expression is associated with increased local invasiveness in head and neck squamous cell carcinomas.

1993 • 222 citations

Purification and characterization of a rabbit bone metalloproteinase that degrades proteoglycan and other connective-tissue components

1983 • 222 citations

Hydrolytic inactivation of a breast carcinoma cell-derived serpin by human stromelysin-3.

1994 • 217 citations

Expression of collagenase‐related metalloproteinase genes in human lung or head and neck tumours

1991 • 210 citations

Stromelysin 3 belongs to a subgroup of proteinases expressed in breast carcinoma fibroblastic cells and possibly implicated in tumor progression.

1993 • 209 citations

Recombinant DNA Technology and Applications

1991 • 206 citations

The origin of matrix metalloproteinases and their familial relationships

1991 • 182 citations

Enhanced production of matrix metalloproteinases and activation of matrix metalloproteinase 2 (gelatinase A) in human gastric carcinomas

1996 • 170 citations

Activation of matrix metalloproteinase 3 (stromelysin) and matrix metalloproteinase 2 (‘gelatinase’) by human neutrophil elastase and cathepsin G

1989 • 166 citations

Kinetics and physiologic relevance of the inactivation of alpha 1-proteinase inhibitor, alpha 1-antichymotrypsin, and antithrombin III by matrix metalloproteinases-1 (tissue collagenase), -2 (72-kDa gelatinase/type IV collagenase), and -3 (stromelysin)

1991 • 135 citations

The 28-kDa N-terminal domain of mouse stromelysin-3 has the general properties of a weak metalloproteinase

1993 • 132 citations

Expression of collagenase (MMP2), stromelysin (MMP3) and tissue inhibitor of the metalloproteinases (TIMP1) in pancreatic and ampullary disease

1996 • 95 citations

Stromelysin-3 expression promotes tumor take in nude mice.

1996 • 92 citations

Detection of mRNAs encoding collagenase I and stromelysin 2 in carcinomas of the head and neck by in situ hybridization.

1991 • 88 citations

Purification of recombinant human prostromelysin. Studies on heat activation to give high-Mr and low-Mr active forms, and a comparison of recombinant with natural stromelysin activities

1991 • 83 citations

Autolytic Activation of Recombinant Human 72 Kilodalton Type IV Collagenase

1995 • 79 citations

Characterization of structural determinants and molecular mechanisms involved in pro-stromelysin-3 activation by 4-aminophenylmercuric acetate and furin-type convertases

1996 • 74 citations

Enhanced Detection of Casein Zymography of Matrix Metalloproteinases

1995 • 74 citations

Increased expression of stromelysin‐3 in basal cell carcinomas

1994 • 46 citations

Expression and regulation of stromelysin and matrilysin by growth factors and oncogenes

1994 • 35 citations

The Role of Stromelysin-1 in Stromal-Epithelial Interactions and Cancer

1996 • 21 citations

Enhancement of baculovirus plaque assay in insect cell monolayers by DEAE-dextran.

1994 • 9 citations

Expression and purification of human matrilysin produced in baculovirus-infected insect cells

1996 • 4 citations