Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism against Salmonella typhimurium infection in mice

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

The Reaction of no With Superoxide

1993 • 2,133 citations

Active Oxygen Species and the Functions of Phagocytic Leukocytes

1980 • 1,124 citations

Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis

1994 • 1,065 citations

Oxidative stress responses in Escherichia coli and Salmonella typhimurium

1991 • 981 citations

The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion

1994 • 863 citations

Nitric oxide, a novel biologic messenger

1992 • 754 citations

Macrophage killing of Leishmania parasite in vivo is mediated by nitric oxide from L-arginine.

1990 • 751 citations

Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide.

1994 • 596 citations

Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not.

1994 • 585 citations

Bacterial Pathogenesis : A Molecular Approach

1994 • 570 citations

Mammalian Nitric Oxide Synthases

1992 • 514 citations

Pathogenesis of influenza virus-induced pneumonia: involvement of both nitric oxide and oxygen radicals.

1996 • 496 citations

Evidence for In Vivo Peroxynitrite Production in Human Acute Lung Injury

1995 • 491 citations

Localization of xanthine oxidase in mammary-gland epithelium and capillary endothelium

1981 • 435 citations

Modulation of Superoxide-dependent Oxidation and Hydroxylation Reactions by Nitric Oxide

1996 • 355 citations

Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages.

1988 • 337 citations

Dependence on O2- generation by xanthine oxidase of pathogenesis of influenza virus infection in mice.

1990 • 336 citations

Role of nitric oxide in parasitic infections

1995 • 326 citations

Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates.

1989 • 320 citations

The Comparative Toxicity of Nitric Oxide and Peroxynitrite to Escherichia coli

1995 • 286 citations

Nitric Oxide Regulation of Tissue Free Radical Injury

1996 • 278 citations

Acceleration of Peroxynitrite Oxidations by Carbon Dioxide

1996 • 277 citations

Nitric Oxide: A Novel Mediator of Inflammation

1995 • 235 citations

Endotoxin triggers the expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in the rat aorta in vivo

1995 • 235 citations

A sensitive fluorometric assay for measuring xanthine dehydrogenase and oxidase in tissues

1989 • 232 citations

Excessive production of nitric oxide in rat solid tumor and its implication in rapid tumor growth

1996 • 173 citations

INFECTION-IMMUNITY IN EXPERIMENTAL SALMONELLOSIS

1966 • 170 citations

Infectious Diseases and Medical Microbiology.

1986 • 169 citations

Cytokine Production Patterns And Lymphoproliferative Responses In Volunteers Orally Immunized With Attenuated Vaccine Strains Of Salmonella Typhi

1994 • 158 citations

Regulation of xanthine dehydrogenase and xanthine oxidase activity and gene expression in cultured rat pulmonary endothelial cells.

1992 • 142 citations

Therapeutic Effects of Imidazolineoxyl N-Oxide Against Endotoxin Shock through Its Direct Nitric Oxide-Scavenging Activity

1994 • 142 citations

Nitric Oxide Affects Microvascular Permeability in the Intact and Inflamed Vasculature

1995 • 123 citations

Molecular cloning of a cDNA coding for mouse liver xanthine dehydrogenase. Regulation of its transcript by interferons in vivo

1992 • 121 citations

Resistance to nitric oxide in Mycobacterium avium complex and its implication in pathogenesis

1993 • 103 citations

Exogenous nitric oxide regulates IFN-gamma plus lipopolysaccharide-induced nitric oxide synthase expression in mouse macrophages.

1995 • 81 citations

Potentiation of Nitric Oxide--Mediated Vasorelaxation by Xanthine Oxidase Inhibitors

1996 • 79 citations

Pronounced enhancement of .NO-dependent antimicrobial action by an .NO-oxidizing agent, imidazolineoxyl N-oxide

1993 • 76 citations

Cytokine Toxicity and Induction of NO Synthase Activity in Cultured Mouse Hepatocytes

1993 • 75 citations

Early midzonal oxidative stress preceding cell death in hypoperfused rat liver

1992 • 72 citations

Expression of inducible nitric oxide synthase and its involvement in pulmonary granulomatous inflammation in rats.

1996 • 70 citations

Liver xanthine oxidase increase in mice in three pathological models

1980 • 57 citations

Interferons induce xanthine dehydrogenase gene expression in L929 cells

1992 • 57 citations

Xanthine oxidase increase in polymorphonuclear leucocytes and macrophages in mice in three pathological situations

1980 • 47 citations

Nitric oxide inactivates xanthine dehydrogenase and xanthine oxidase in interferon-gamma-stimulated macrophages.

1994 • 36 citations

Pathogenesis of cytomegalovirus-associated pneumonitis in ICR mice: possible involvement of superoxide radicals

1992 • 24 citations

Expression of xanthine oxidase activity by murine leukocytes.

1990 • 20 citations

Granulation in livers of mice infected with Salmonella typhimurium is caused by superoxide released from host phagocytes

1995 • 17 citations

Changes in hepatic superoxide dismutase and xanthine oxidase activity in mice infected with Salmonella typhimurium and Pseudomonas aeruginosa

1988 • 13 citations