Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages.

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Macrophage Cytotoxicity: Role for L-Arginine Deiminase and Imino Nitrogen Oxidation to Nitrite

1987 • 1,533 citations

Defensins. Natural peptide antibiotics of human neutrophils.

1985 • 1,411 citations

Mammalian nitrate biosynthesis: mouse macrophages produce nitrite and nitrate in response to Escherichia coli lipopolysaccharide.

1985 • 1,146 citations

L-arginine is required for expression of the activated macrophage effector mechanism causing selective metabolic inhibition in target cells.

1987 • 958 citations

Increased superoxide anion production by immunologically activated and chemically elicited macrophages

1978 • 823 citations

Nitrate biosynthesis in man.

1981 • 677 citations

Nitrate Synthesis in the Germfree and Conventional Rat

1981 • 551 citations

Recombinant mouse gamma interferon induces the priming step in macrophage activation for tumor cell killing.

1983 • 447 citations

Murine cytotoxic activated macrophages inhibit aconitase in tumor cells. Inhibition involves the iron-sulfur prosthetic group and is reversible.

1986 • 421 citations

Sites of inhibition of mitochondrial electron transport in macrophage-injured neoplastic cells.

1982 • 349 citations

Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxide.

1985 • 320 citations

Activated macrophages kill tumour cells by releasing arginase

1978 • 307 citations

Chronic cryptococcal meningitis: a new experimental model in rabbits.

1980 • 278 citations

Magnitude of the host nutritional responses to infection

1977 • 262 citations

Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediates.

1979 • 236 citations

Mammalian nitrate biosynthesis: incorporation of 15NH3 into nitrate is enhanced by endotoxin treatment.

1983 • 211 citations

Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration.

1980 • 186 citations

Iron depletion: Possible cause of tumor cell cytotoxicity induced by activated macrophages

1984 • 183 citations

A Reevaluation of the Roles of the O2-Dependent and O2-Independent Microbicidal Systems of Phagocytes

1983 • 143 citations

Diagnostic Laboratory Hematology.

1968 • 138 citations

Pigment production by Cryptococcus neoformans from para- and ortho-Diphenols: effect of the nitrogen source

1975 • 123 citations

Macrophage-mediated fungistasis in vitro: requirements for intracellular and extracellular cytotoxicity.

1986 • 79 citations

Associations of ninhydrin-reacting compounds in the seeds of 49 species of Lathyrus

1962 • 76 citations

Fungicidal activity of rabbit alveolar and peritoneal macrophages against Candida albicans

1980 • 69 citations

Leukocyte endogenous mediator alters protein dynamics in rats

1983 • 61 citations

Subcellular location and properties of bactericidal factors from human neutrophils.

1986 • 55 citations

Acquired cellular immunity: Extracellular killing of Listeria monocytogenes by a product of immunologically activated macrophages

1974 • 55 citations

Activated macrophages secrete a soluble factor that inhibits mitochondrial respiration of tumor cells.

1984 • 52 citations

Macrophage-mediated fungistasis: requirement for a macromolecular component in serum.

1986 • 32 citations

Oxidation of ammonia and hydroxylamine to nitrate in the rat and in vitro

1984 • 31 citations

Activated oxygen and mammalian nitrate biosynthesis

1984 • 21 citations

Effects of activated macrophages on tumor target cells in discrete phases of the cell cycle.

1980 • 20 citations

Cytostatic Effects of Activated Macrophages on Tumor Target Cells: Inhibition of Cytotoxic Action of Ara-C

1980 • 5 citations