Messenger RNAs are recruited for nuclear export during transcription

Guide to Yeast Genetics and Molecular Biology

1993 • 2,377 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

2000 • 1,049 citations

Guide to yeast genetics and molecular biology

1992 • 1,032 citations

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

2000 • 923 citations

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

1997 • 905 citations

Analysis of Chromatin Structure byin VivoFormaldehyde Cross-Linking

1997 • 610 citations

RNA polymerase II and the integration of nuclear events

2000 • 561 citations

TAP, the Human Homolog of Mex67p, Mediates CTE-Dependent RNA Export from the Nucleus

1998 • 557 citations

The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans

2000 • 514 citations

mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain

1997 • 467 citations

Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae

1998 • 460 citations

Binding of TBP to promoters in vivo is stimulated by activators and requires Pol II holoenzyme

1999 • 457 citations

The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human

1999 • 431 citations

The TATA-binding protein is required for transcription by all three nuclear RNA polymerases in yeast cells

1992 • 392 citations

Dynamic association of capping enzymes with transcribing RNA polymerase II

2000 • 384 citations

Splicing is required for rapid and efficient mRNA export in metazoans

1999 • 375 citations

Isolation and characterization of RAT1: an essential gene of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA.

1992 • 370 citations

In vivo transcriptional pausing and cap formation on three Drosophila heat shock genes.

1993 • 361 citations

Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export

2000 • 351 citations

The C-terminal domain of the largest subunit of RNA polymerase II interacts with a novel set of serine/arginine-rich proteins.

1996 • 351 citations

The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates

2000 • 329 citations

Pre-mRNA Splicing Imprints mRNA in the Nucleus with a Novel RNA-Binding Protein that Persists in the Cytoplasm

2000 • 326 citations

A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix.

1996 • 324 citations

Active Disruption of an RNA-Protein Interaction by a DExH/D RNA Helicase

2001 • 304 citations

Transcription factor TFIID recruits factor CPSF for formation of 3′ end of mRNA

1997 • 301 citations

A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export.

1996 • 298 citations

Arginine methylation facilitates the nuclear export of hnRNP proteins

1998 • 287 citations

Dbp5p/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA export

1998 • 272 citations

Nuclear mRNA Export Requires Complex Formation between Mex67p and Mtr2p at the Nuclear Pores

1998 • 263 citations

General requirement for RNA polymerase II holoenzymes in vivo.

1995 • 249 citations

REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus

2001 • 248 citations

The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences

1999 • 246 citations

A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export.

1996 • 232 citations

Binding of the Mex67p/Mtr2p Heterodimer to Fxfg, Glfg, and Fg Repeat Nucleoporins Is Essential for Nuclear mRNA Export

2000 • 229 citations

Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3′-end formation in yeast

1997 • 225 citations

The Spt components of SAGA facilitate TBP binding to a promoter at a post-activator-binding step in vivo

1999 • 220 citations

A Pre-mRNA-Binding Protein Accompanies the RNA from the Gene through the Nuclear Pores and into Polysomes

1996 • 220 citations

Rat8p/Dbp5p is a shuttling transport factor that interacts with Rat7p/Nup159p and Gle1p and suppresses the mRNA export defect of xpo1-1 cells

1999 • 209 citations

Mtr10p functions as a nuclear import receptor for the mRNA-binding protein Npl3p

1998 • 186 citations

Classical mutagenesis techniques

2002 • 176 citations

A yeast RNA-binding protein shuttles between the nucleus and the cytoplasm.

1994 • 164 citations

The addition of 5′ cap structures occurs early in hnRNA synthesis and prematurely terminated molecules are capped

1980 • 161 citations

The RNA export factor Gle1p is located on the cytoplasmic fibrils of the NPC and physically interacts with the FG-nucleoporin Rip1p, the DEAD-box protein Rat8p/Dbp5p and a new protein Ymr255p

1999 • 155 citations

The Yeast hnRNP-like Protein Hrp1/Nab4 Marks a Transcript for Nonsense-Mediated mRNA Decay

2000 • 154 citations

[18] Classical mutagenesis techniques

1991 • 147 citations

Phosphorylation by Sky1p promotes Npl3p shuttling and mRNA dissociation

2001 • 141 citations

YEAST GENETICS TO DISSECT THE NUCLEAR PORE COMPLEX AND NUCLEOCYTOPLASMIC TRAFFICKING

1997 • 139 citations

Characterization of nuclear polyadenylated RNA-binding proteins in Saccharomyces cerevisiae.

1994 • 133 citations

A mutant nuclear protein with similarity to RNA binding proteins interferes with nuclear import in yeast.

1992 • 119 citations

A Distinct and Parallel Pathway for the Nuclear Import of an mRNA-binding Protein

1997 • 104 citations

Potential RNA Binding Proteins in Saccharomyces cerevisiae Identified as Suppressors of Temperature-Sensitive Mutations in NPL3

1996 • 91 citations

In vitro transcription from the adenovirus 2 major late promoter utilizing templates truncated at promoter-proximal sites.

1984 • 90 citations

TBP mutants defective in activated transcription in vivo.

1995 • 87 citations

Nuclear mRNA accumulation causes nucleolar fragmentation in yeast mtr2 mutant.

1994 • 79 citations

Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export

1999 • 77 citations

A yeast protein that bidirectionally affects nucleocytoplasmic transport

1995 • 75 citations

A Yeast RNA-Binding Protein Shuttles between the Nucleus and the Cytoplasm

1994 • 69 citations

7The Yeast mRNA-binding Protein Npl3p Interacts with the Cap-binding Complex

2000 • 66 citations

A protein of the SR family of splicing factors binds extensively to exonic Balbiani ring pre-mRNA and accompanies the RNA from the gene to the nuclear pore.

1996 • 66 citations

Genetic Analysis of the Large Subunit of Yeast Transcription Factor IIE Reveals Two Regions with Distinct Functions

1997 • 58 citations

REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus

2001 • 46 citations

Enhancement of mRNA nuclear transport by promoter elements

1987 • 44 citations

The hrp23 Protein in the Balbiani Ring Pre-mRNP Particles Is Released Just before or at the Binding of the Particles to the Nuclear Pore Complex

1998 • 39 citations

Characterization of the ptr6+ Gene in Fission Yeast: A Possible Involvement of a Transcriptional Coactivator TAF in Nucleocytoplasmic Transport of mRNA

1999 • 30 citations