Isolation and characterization of RAT1: an essential gene of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Methods in yeast genetics

1979 • 7,824 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

[10] 5-Fluoroorotic acid as a selective agent in yeast molecular genetics

1987 • 1,375 citations

A rapid and simple method for preparation of RNA fromSaccharomyces cerevisiae

1990 • 1,340 citations

Changes in size and secondary structure of the ribosomal transcription unit during vertebrate evolution

1975 • 1,188 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

Identification of two distinct regulatory regions adjacent to the human β-interferon gene

1983 • 1,076 citations

DNA sequence required for efficient transcription termination in yeast

1982 • 1,014 citations

PRE-mRNA SPLICING

1986 • 673 citations

rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA.

1989 • 634 citations

Identification and characterization of a nuclear pore complex protein

1986 • 610 citations

Splice site selection, rate of splicing, and alternative splicing on nascent transcripts.

1988 • 539 citations

Regulation by HIV Rev depends upon recognition of splice sites

1989 • 517 citations

Correlation between structure and mass distribution of the nuclear pore complex and of distinct pore complex components.

1990 • 510 citations

COMPLEX TRANSCRIPTIONAL UNITS: DIVERSITY IN GENE EXPRESSION BY ALTERNATIVE RNA PROCESSING

1986 • 486 citations

5'-terminal cap structure in eucaryotic messenger ribonucleic acids

1980 • 463 citations

Codon preferences in free-living microorganisms

1990 • 452 citations

Core filaments of the nuclear matrix.

1990 • 436 citations

Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization

1989 • 434 citations

Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm

1989 • 417 citations

Monomethylated cap structures facilitate RNA export from the nucleus

1990 • 411 citations

Actively transcribed genes are associated with the nuclear matrix

1983 • 396 citations

RNA TRANSPORT FROM NUCLEUS TO CYTOPLASM IN CHIRONOMUS SALIVARY GLANDS

1966 • 361 citations

The ovalbumin gene is associated with the nuclear matrix of chicken oviduct cells

1982 • 356 citations

Eucaryotic RNA Polymerase Conditional Mutant that Rapidly Ceases mRNA Synthesis

1987 • 353 citations

[7] Random cloning and sequencing by the M13/dideoxynucleotide chain termination method

1987 • 292 citations

Translocation of RNA-coated gold particles through the nuclear pores of oocytes.

1988 • 292 citations

Genetic map of Saccharomyces cerevisiae, edition 10

1989 • 276 citations

A set of synthetic oligodeoxyribonucleotide primers for DNA sequencing in the plasmid vector pBR322

1981 • 260 citations

Structure and Function of Nuclear and Cytoplasmic Ribonucleoprotein Particles

1986 • 243 citations

Nascent pre-mRNA transcripts are associated with nuclear regions enriched in splicing factors.

1991 • 239 citations

A yeast mutant which accumulates precursor tRNAs

1978 • 231 citations

Primary structure analysis of an integral membrane glycoprotein of the nuclear pore.

1989 • 228 citations

The yeast RNA1 gene product necessary for RNA processing is located in the cytosol and apparently excluded from the nucleus.

1990 • 228 citations

Mature mRNA 3′ end formation stimulates RNA export from the nucleus.

1991 • 222 citations

Pre-mRNA splicing and the nuclear matrix.

1987 • 220 citations

The nuclear matrix: Structure and composition

1988 • 220 citations

The NUP1 gene encodes an essential component of the yeast nuclear pore complex

1990 • 219 citations

Visualization of a filamentous nucleoskeleton with a 23 nm axial repeat.

1988 • 216 citations

Pre-mRNA Splicing in Yeast

1989 • 209 citations

The effect of temperature-sensitive RNA mutants on the transcription products from cloned ribosomal protein genes of yeast

1981 • 206 citations

Interaction between mRNA, ribosomes and the cytoskeleton

1991 • 196 citations

NSP1: A yeast nuclear envelope protein localized at the nuclear pores exerts its essential function by its carboxy-terminal domain

1990 • 180 citations

Disruption of the gene XRN1, coding for a 5′→3′ exoribonuclease, restricts yeast cell growth

1990 • 152 citations

Preservation of specific RNA distribution within the chromatin-depleted nuclear substructure demonstrated by in situ hybridization coupled with biochemical fractionation.

1991 • 139 citations

RNA Processing Generates the Mature 3′ End of Yeast CYC1 Messenger RNA in Vitro

1988 • 129 citations

Heat shock proteins affect RNA processing during the heat shock response of Saccharomyces cerevisiae.

1991 • 127 citations

kem mutations affect nuclear fusion in Saccharomyces cerevisiae.

1990 • 117 citations

[30] Labeling of RNA and phosphoproteins in Saccharomyces cerevisiae

1991 • 116 citations

The association of transcribed genes with the nuclear matrix ofDrosophilacells during heat shock

1985 • 114 citations

Molecular and genetic analysis of the gene encoding the Saccharomyces cerevisiae strand exchange protein Sep1.

1991 • 104 citations

Splicing Precedes Polyadenylation during Drosophila E74A Transcription

1990 • 100 citations

The NUF1 gene encodes an essential coiled-coil related protein that is a potential component of the yeast nucleoskeleton.

1992 • 98 citations

Cloning and characterization of DST2, the gene for DNA strand transfer protein beta from Saccharomyces cerevisiae.

1991 • 95 citations

Transport of mRNA from Nucleus to Cytoplasm

1987 • 93 citations

A 5′ → 3′ exoribonuclease of Saccharomyces cerevisiae: Size and novel substrate specificity

1987 • 92 citations

The Role of Cytoplasmic Membranes in Controlling the Transport of Nuclear Messenger RNA and Initiation of Protein Synthesis

1974 • 86 citations

A beginning to the biochemistry of polyadenylation

1988 • 84 citations

Association of globin RNA and its precursors with the chicken erythroblast nuclear matrix

1982 • 79 citations

A nuclear cap binding protein from HeLa cells

1990 • 78 citations

Autonomous splicing and complementation of in vivo-assembled spliceosomes.

1989 • 78 citations

rarmutations which increase artificial chromosome stability inSaccharomyces cerevisiaeidentify transcription and recombination proteins

1991 • 76 citations

Regulatory DNA‐binding proteins in yeast: An overview

1990 • 74 citations

Nuclear RNA-binding Proteins

1991 • 69 citations

Nuclear mRNA export

1991 • 69 citations

Nuclear matrix DNA from chicken erythrocytes contains beta-globin gene sequences.

1984 • 58 citations

Polyadenylate metabolism in the nuclei and cytoplasm of Saccharomyces cerevisiae.

1975 • 58 citations

The composition and morphology of yeast nuclear scaffolds

1990 • 57 citations

Elongation by Drosophila RNA polymerase II. Transcription of 3′-extended DNA templates.

1988 • 55 citations

Renaturase and ribonuclease H: a novel mechanism that influences transcript displacement by RNA polymerase II in vitro

1988 • 55 citations

Requirement for acidic amino acid residues immediately N-terminal to the conserved domain of Saccharomyces cerevisiae TFIID.

1991 • 54 citations

Purification and Characterization of a DNA-pairing and Strand Transfer Activity from Mitotic Saccharomyces cerevisiae

1989 • 49 citations

Characterization of an essential Saccharomyces cerevisiae gene related to RNA processing: cloning of RNA1 and generation of a new allele with a novel phenotype.

1985 • 48 citations

Recombination and RNA processing: a common strand?

1991 • 47 citations

Organization of the nuclear pore complex in Saccharomyces cerevisiae

1989 • 46 citations

Isolation and characterization of the RNA2, RNA3, and RNA11 genes of Saccharomyces cerevisiae.

1984 • 42 citations

[30] Sequence and structural requirements for efficient translation in yeast

1990 • 42 citations

Messenger RNA transport and localization

1990 • 32 citations

Attachment of transcriptionally active DNA sequences to the nucleoskeleton under isotonic conditions

1988 • 21 citations

Between nucleus and cytoplasm

1992 • 19 citations

Multiple elements regulate expression of the cell cycle-regulated thymidylate synthase gene of Saccharomyces cerevisiae

1988 • 8 citations