REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus
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References (26)
Conserved Structures and Diversity of Functions of RNA-Binding Proteins
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The HIV-1 Rev Activation Domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs
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The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
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TAP, the Human Homolog of Mex67p, Mediates CTE-Dependent RNA Export from the Nucleus
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The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans
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Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex
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Splicing is required for rapid and efficient mRNA export in metazoans
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REF, an evolutionarily conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export
2000 • 365 citations
Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export
2000 • 351 citations
Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon–exon junctions
2000 • 337 citations
The Mkk3/6-p38–Signaling Cascade Alters the Subcellular Distribution of Hnrnp A1 and Modulates Alternative Splicing Regulation
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Pre-mRNA Splicing Imprints mRNA in the Nucleus with a Novel RNA-Binding Protein that Persists in the Cytoplasm
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Nuclear export of different classes of RNA is mediated by specific factors
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ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function.
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The cellular organization of gene expression
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The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway
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TAP (NXF1) Belongs to a Multigene Family of Putative RNA Export Factors with a Conserved Modular Architecture
2000 • 224 citations
The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export
1997 • 171 citations
The Nucleoporin Nup153 Plays a Critical Role in Multiple Types of Nuclear Export
1999 • 142 citations
Deciphering the cellular pathway for transport of poly(A)-binding protein II
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A Human Nuclear-Localized Chaperone that Regulates Dimerization, DNA Binding, and Transcriptional Activity of bZIP Proteins
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Nucleocytoplasmic shuttling signals: two for the price of one
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YRA1, an essential Saccharomyces cerevisiae gene, encodes a novel nuclear protein with RNA annealing activity.
1997 • 56 citations
Roles of U4 and U6 snRNAs in the assembly of splicing complexes.
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Autoantibodies to transcriptional regulation proteins DEK and ALY in a patient with systemic lupus erythematosus
1999 • 21 citations
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