Rho-associated Kinase of Chicken Gizzard Smooth Muscle

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

1997 • 2,847 citations

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

1996 • 1,964 citations

Physiology of the Gastrointestinal Tract.

1987 • 1,948 citations

Signal transduction and regulation in smooth muscle

1994 • 1,915 citations

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

1994 • 1,520 citations

Chelerythrine is a potent and specific inhibitor of protein kinase C

1990 • 1,208 citations

Formation of Actin Stress Fibers and Focal Adhesions Enhanced by Rho-Kinase

1997 • 1,085 citations

Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho.

1996 • 1,045 citations

The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

1996 • 872 citations

The p160 RhoA-Binding Kinase ROKα Is a Member of a Kinase Family and Is Involved in the Reorganization of the Cytoskeleton

1996 • 866 citations

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

1997 • 819 citations

ROCK‐I and ROCK‐II, two isoforms of Rho‐associated coiled‐coil forming protein serine/threonine kinase in mice

1996 • 757 citations

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate

1994 • 749 citations

A Novel Serine/Threonine Kinase Binding the Ras-related RhoA GTPase Which Translocates the Kinase to Peripheral Membranes

1995 • 711 citations

Rho-associated Kinase Directly Induces Smooth Muscle Contraction through Myosin Light Chain Phosphorylation

1997 • 576 citations

Rho GTPases

1998 • 534 citations

Wortmannin, a microbial product inhibitor of myosin light chain kinase.

1992 • 434 citations

Identification of a Putative Target for Rho as the Serine-Threonine Kinase Protein Kinase N

1996 • 417 citations

Myosin light chain phosphatase: subunit composition, interactions and regulation.

1998 • 391 citations

Protein Kinase N (PKN) and PKN-Related Protein Rhophilin as Targets of Small GTPase Rho

1996 • 384 citations

Rhotekin, a New Putative Target for Rho Bearing Homology to a Serine/Threonine Kinase, PKN, and Rhophilin in the Rho-binding Domain

1996 • 378 citations

Pharmacology of Protein Kinase Inhibitors

1992 • 367 citations

Pleckstrin Homology Domain-mediated Membrane Association and Activation of the β-Adrenergic Receptor Kinase Requires Coordinate Interaction with Gβγ Subunits and Lipid

1995 • 360 citations

Smooth muscle caldesmon. Rapid purification and F-actin cross-linking properties.

1984 • 321 citations

G protein-mediated inhibition of myosin light-chain phosphatase in vascular smooth muscle.

1991 • 319 citations

Casein kinase type II is involved in the inhibition by 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole of specific RNA polymerase II transcription.

1986 • 285 citations

Characterization of the myosin-binding subunit of smooth muscle myosin phosphatase.

1994 • 261 citations

Myosin light chain kinases.

1997 • 247 citations

Identification, phosphorylation, and dephosphorylation of a second site for myosin light chain kinase on the 20,000-dalton light chain of smooth muscle myosin.

1986 • 246 citations

Arachidonic acid inhibits myosin light chain phosphatase and sensitizes smooth muscle to calcium.

1992 • 232 citations

Translocation of rhoA Associated with Ca2+ Sensitization of Smooth Muscle

1997 • 218 citations

Association of the Myosin-binding Subunit of Myosin Phosphatase and Moesin: Dual Regulation of Moesin Phosphorylation by Rho-associated Kinase and Myosin Phosphatase

1998 • 210 citations

Regulation of the Association of Adducin with Actin Filaments by Rho-associated Kinase (Rho-kinase) and Myosin Phosphatase

1998 • 209 citations

Selective inhibitors of Ca2+-binding modulator of phosphodiesterase produce vascular relaxation and inhibit actin-myosin interaction.

1979 • 201 citations

Phosphorylation of the Large Subunit of Myosin Phosphatase and Inhibition of Phosphatase Activity

1996 • 197 citations

The Low Molecular Weight GTPase Rho Regulates Myofibril Formation and Organization in Neonatal Rat Ventricular Myocytes

1998 • 194 citations

Effects of Ca2+ on the conformation and enzymatic activity of smooth muscle myosin.

1985 • 170 citations

A novel partner for the GTP‐bound forms of rho and rac

1995 • 166 citations

GTP gamma S-dependent regulation of smooth muscle contractile elements

1992 • 139 citations

Selective purification of the 20,000-Da light chains of smooth muscle myosin

1983 • 129 citations

Correlation of enzymatic properties and conformation of smooth muscle myosin

1983 • 124 citations

S‐Carboxymethylation of proteins transferred onto polyvinylidene difluoride membranes followed by in situ protease digestion and amino acid microsequencing

1992 • 107 citations

Possible role of atypical protein kinase C activated by arachidonic acid in Ca2+ sensitization of rabbit smooth muscle.

1997 • 102 citations

Interactions and Properties of Smooth Muscle Myosin Phosphatase

1996 • 84 citations

Arachidonic acid and diacylglycerol release associated with inhibition of myosin light chain dephosphorylation in rabbit smooth muscle.

1995 • 65 citations

Interaction of Smooth Muscle Myosin Phosphatase with Phospholipids

1997 • 63 citations

Effects of magnesium chloride on smooth muscle actomyosin adenosine 5'-triphosphatase activity, myosin conformation, and tension development in glycerinated smooth muscle fibers

1984 • 60 citations

Interaction of smooth muscle tropomyosin and smooth muscle myosin. Effect on the properties of myosin

1989 • 9 citations