AT1 and AT2 receptor expression and blockade after acute ischemia-reperfusion in isolated working rat hearts

Effects of angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor antagonists in rats with heart failure. Role of kinins and angiotensin II type 2 receptors.

1997 • 603 citations

Recent Progress in Angiotensin II Type 2 Receptor Research in the Cardiovascular System

1999 • 472 citations

Regulation of gene transcription of angiotensin II receptor subtypes in myocardial infarction.

1995 • 441 citations

Subclasses of angiotensin II binding sites and their functional significance.

1990 • 375 citations

Rat angiotensin II (type 1A) receptor mRNA regulation and subtype expression in myocardial growth and hypertrophy.

1993 • 286 citations

Cardiac-specific overexpression of angiotensin II AT2 receptor causes attenuated response to AT1 receptor-mediated pressor and chronotropic effects.

1998 • 259 citations

Isoform-Selective Activation of Protein Kinase C by Nitric Oxide in the Heart of Conscious Rabbits

1999 • 258 citations

Characterization of angiotensin II receptor subtypes in rat heart.

1992 • 236 citations

Intracellular Trafficking of Angiotensin II and its AT₁and AT₂Receptors: Evidence for Selective Sorting of Receptor and Ligand

1997 • 227 citations

Ischemia-Reperfusion of Rat Myocardium Activates Nuclear Factor-κB and Induces Neutrophil Infiltration Via Lipopolysaccharide-Induced CXC Chemokine

2001 • 203 citations

Regulation, Chamber Localization, and Subtype Distribution of Angiotensin II Receptors in Human Hearts

1995 • 191 citations

AT ₁ and AT ₂ Angiotensin Receptor Gene Expression in Human Heart Failure

1997 • 188 citations

Pretreatment with angiotensin II activates protein kinase C and limits myocardial infarction in isolated rabbit hearts

1995 • 180 citations

Infarct size reduction by AT1-receptor blockade through a signal cascade of AT2-receptor activation, bradykinin and prostaglandins in pigs

1998 • 178 citations

Angiotensin II Receptor Blockade After Myocardial Infarction in Rats

1992 • 178 citations

Differential gene expression and regulation of angiotensin II receptor subtypes in rat cardiac fibroblasts and cardiomyocytes in culture.

1994 • 155 citations

Modulation of the Renin-Angiotensin Pathway Through Enzyme Inhibition and Specific Receptor Blockade in Pacing-Induced Heart Failure

1997 • 154 citations

Simvastatin reduces reperfusion injury by modulating nitric oxide synthase expression: an ex vivo study in isolated working rat hearts

2001 • 153 citations

Sciatic nerve transection evokes lasting up-regulation of angiotensin AT2 and AT1 receptor mRNA in adult rat dorsal root ganglia and sciatic nerves

1998 • 121 citations

Relative effects of alpha 1-adrenoceptor blockade, converting enzyme inhibitor therapy, and angiotensin II subtype 1 receptor blockade on ventricular remodeling in the dog.

1994 • 110 citations

Immunolocalization of Subtype 2 Angiotensin II (AT ₂ ) Receptor Protein in Rat Heart

1998 • 106 citations

Modulation of the Renin-Angiotensin Pathway Through Enzyme Inhibition and Specific Receptor Blockade in Pacing-Induced Heart Failure

1997 • 103 citations

Increase in Angiotensin II Type 1 Receptor Expression Immediately After Ischemia-Reperfusion in Isolated Rat Hearts

1997 • 102 citations

Opposite Effects of Angiotensin AT ₁ and AT ₂ Receptor Antagonists on Recovery of Mechanical Function After Ischemia-Reperfusion in Isolated Working Rat Hearts

1996 • 98 citations

Regulation of Angiotensin II Type 1 Receptor mRNA and Protein in Angiotensin II–Induced Hypertension

1999 • 92 citations

Short-Term Effects of Rapid Pacing on mRNA Level of Voltage-Dependent K ⁺ Channels in Rat Atrium

2000 • 90 citations

Cardioprotective effect of the angiotensin II type 1 receptor antagonist TCV-116 on ischemia-reperfusion injury

1994 • 89 citations

Adenosine-induced late preconditioning in mouse hearts: role of p38 MAP kinase and mitochondrial K_ATPchannels

2001 • 84 citations

Effects of Angiotensin-Converting Enzyme Inhibition and Angiotensin II AT1 Receptor Antagonism on Cardiac Parameters in Left Ventricular Hypertrophy

1997 • 78 citations

Alterations in Fatty Acid Oxidation During Reperfusion of the Heart After Myocardial Ischemia

1997 • 78 citations

Effects of oxidative stress on the expression of antioxidative defense enzymes in spontaneously hypertensive rat hearts

2000 • 77 citations

Brief murine myocardial I/R induces chemokines in a TNF-α-independent manner: role of oxygen radicals

2001 • 66 citations

“Cardioprotection” by ACE-inhibitors in acute myocardial ischemia and infarction?

1993 • 49 citations

Critical Role of AT ₁ Receptor Expression After Ischemia/Reperfusion in Isolated Rat Hearts

1998 • 47 citations

Cardioprotection after angiotensin II type 1 blockade involves angiotensin II type 2 receptor expression and activation of protein kinase C-ε in acutely reperfused myocardial infarction in the dog

2000 • 42 citations

Angiotensin II Receptor Subtypes and Biological Responses in the Rat Heart

1993 • 40 citations

Comparison of Effects of Angiotensin-Converting Enzyme Inhibition with Those of Angiotensin II Receptor Antagonism on Functional and Metabolic Recovery in Postischemic Working Rat Heart as Studied by [31P] Nuclear Magnetic Resonance

1994 • 37 citations

Reactive Oxygen Species–Mediated Homologous Downregulation of Angiotensin II Type 1 Receptor mRNA by Angiotensin II

2001 • 32 citations

Role of bradykinins and nitric oxide in the AT2 receptor-mediated hypotension

2000 • 32 citations

Effect of the novel angiotensin II type 1 receptor antagonist L-158,809 on acute infarct expansion and acute anterior myocardial infarction in the dog.

1998 • 27 citations

Increased vulnerability of hypertrophied myocardium to ischemia and reperfusion injury. Relation to cardiac renin-angiotensin system.

1995 • 20 citations

Protection against myocardial dysfunction induced by global ischemia-reperfusion by antisense-oligodeoxynucleotides directed at beta(1)-adrenoceptor mRNA.

2000 • 17 citations

Intrinsic ANG II type 1 receptor stimulation contributes to recovery of postischemic mechanical function

1998 • 13 citations

The deleterious effects of exogenous angiotension I and angiotensin II on myocardial ischemia-reperfusion injury.

1994 • 11 citations

Modulation of Myocardial SOD and iNOS During Ischemia–reperfusion by Antisense Directed at ACE mRNA

2000 • 8 citations

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