Regulation, Chamber Localization, and Subtype Distribution of Angiotensin II Receptors in Human Hearts

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

A Comparison of Enalapril with Hydralazine–Isosorbide Dinitrate in the Treatment of Chronic Congestive Heart Failure

1991 • 2,867 citations

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.

1993 • 1,420 citations

Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure.

1986 • 1,297 citations

Effect of Captopril on Progressive Ventricular Dilatation after Anterior Myocardial Infarction

1988 • 1,119 citations

Identification of angiotensin II receptor subtypes

1989 • 825 citations

A quantitative analysis of beta-adrenergic receptor interactions: resolution of high and low affinity states of the receptor by computer modeling of ligand binding data.

1980 • 545 citations

Angiotensin II is mitogenic in neonatal rat cardiac fibroblasts.

1993 • 391 citations

Identification of functional angiotensin II receptors on rat cardiac fibroblasts.

1993 • 361 citations

Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells

1990 • 358 citations

Remodeling and reparation of the cardiovascular system

1992 • 323 citations

Rat angiotensin II (type 1A) receptor mRNA regulation and subtype expression in myocardial growth and hypertrophy.

1993 • 286 citations

Calculating receptor number from binding experiments using same compound as radioligand and competitor

1989 • 250 citations

Characterization of angiotensin II receptor subtypes in rat heart.

1992 • 236 citations

Localization of angiotensin converting enzyme in rat heart.

1991 • 205 citations

Angiotensin II increases spontaneous contractile frequency and stimulates calcium current in cultured neonatal rat heart myocytes: insights into the underlying biochemical mechanisms.

1988 • 199 citations

Selective gene expression in failing human heart. Quantification of steady-state levels of messenger RNA in endomyocardial biopsies using the polymerase chain reaction.

1991 • 199 citations

Regulation of angiotensin II receptors on ventricular myocytes after myocardial infarction in rats.

1993 • 185 citations

Externalization of beta-adrenergic receptors promoted by myocardial ischemia

1985 • 164 citations

Angiotensin II Receptors in Normal and Failing Human Hearts*

1989 • 153 citations

PCR: Clinical Diagnostics and Research

1992 • 138 citations

Angiotensin II AT2 receptors do not interact with guanine nucleotide binding proteins

1991 • 137 citations

Role of receptor cycling in the regulation of angiotensin II surface receptor number and angiotensin II uptake in rat vascular smooth muscle cells.

1989 • 131 citations

Direct myocardial effects of angiotensin II

1971 • 128 citations

Identification and characterization of angiotensin II receptor subtypes in rabbit ventricular myocardium

1990 • 122 citations

Identification and characterization of the rabbit angiotensin II myocardial receptor.

1984 • 122 citations

PCR: Clinical Diagnostics and Research

1992 • 117 citations

Angiotensin I and II exert inotropic effects in atrial but not in ventricular human myocardium. An in vitro study under physiological experimental conditions.

1993 • 100 citations

High affinity angiotensin II receptors in myocardial sarcolemmal membranes. Characterization of receptors and covalent linkage of 125I-angiotensin II to a membrane component of 116,000 daltons.

1984 • 75 citations

Characterization of the rabbit ventricular myocardial receptor for angiotensin II. Evidence for two sites of different affinities and specificities.

1983 • 74 citations

Angiotensin Converting Enzyme Inhibition in Heart, Kidney, and Serum Studied Ex Vivo after Administration of Zofenopril, Captopril, and Lisinopril

1991 • 51 citations

Identification and characterization of angiotensin II receptors in cardiac sarcolemma

1982 • 39 citations

Distribution and function of human ventricular beta adrenergic receptors in congestive heart failure

1989 • 34 citations

Genetic Polymorphisms of the Angiotensin II type 1 (AT1) Receptor Gene

1994 • 26 citations